Patents by Inventor Hervé Bastian

Hervé Bastian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In vitro production of a cell population using feeder cells
    Patent number: 8722401
    Abstract: A method for the in vitro production of a cell population P? from a cell population P, the production requiring the presence of at least one factor which is expressed by feeder cells, wherein a) feeder cells proliferate at a temperature T1, b) proliferated feeder cells are contacted with the cell population P, c) the cell mixture obtained at step (b) is cultivated at a temperature T2 which is chosen such that the cell population P proliferates and the feeder cells do not proliferate, the at least one factor being expressed by the feeder cells, and d) the cell population P? so produced is recovered. Advantageously, the production consists in an expansion, the feeder cells are insect feeder cells and the cell population P to be expanded is a T lymphocyte population, preferably a Trl lymphocyte population.
    Type: Grant
    Filed: April 18, 2006
    Date of Patent: May 13, 2014
    Assignees: TxCell, Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Hervé Groux, Françoise Cottrez, Hervé Bastian, Valérie Brun
  • IL-13 PRODUCING TR1-LIKE CELLS AND USE THEREOF
    Publication number: 20130101568
    Abstract: The present invention relates to an isolated Tr1-like cell population capable of producing IL-13, the population having immunosuppressive activities; methods for identifying/isolating/enriching the population and its uses thereof.
    Type: Application
    Filed: June 30, 2011
    Publication date: April 25, 2013
    Applicant: TXCELL
    Inventors: Arnaud Foussat, Herve Bastian, Valerie Brun, Brigitte Quatannens
  • NEW METHODS FOR ISOLATING TR1 CELLS
    Publication number: 20130034528
    Abstract: The present invention relates to methods for isolating Tr1 cells, resting Tr1 cells and/or activated Tr1 cells, to methods for enriching or depleting a cell population in Tr1 cells, resting Tr1 cells and/or activated Tr1 cells and to methods and kits for treating chronic inflammatory diseases, autoimmune diseases, allergic diseases, cancer and organ transplantation conditions.
    Type: Application
    Filed: April 15, 2011
    Publication date: February 7, 2013
    Applicant: TXCELL
    Inventors: Arnaud Foussat, Valerie Brun, Nathalie Belmonte, Herve Bastian, Brigitte Quattannens
  • In Vitro Production of a Cell Population Using Feeder Cells
    Publication number: 20090221070
    Abstract: A method for the in vitro production of a cell population P? from a cell population P, the production requiring the presence of at least one factor which is expressed by feeder cells, wherein a) feeder cells proliferate at a temperature T1, b) proliferated feeder cells are contacted with the cell population P, c) the cell mixture obtained at step (b) is cultivated at a temperature T2 which is chosen such that the cell population P proliferates and the feeder cells do not proliferate, the at least one factor being expressed by the feeder cells, and d) the cell population P? so produced is recovered. Advantageously, the production consists in an expansion, the feeder cells are insect feeder cells and the cell population P to be expanded is a T lymphocyte population, preferably a Trl lymphocyte population.
    Type: Application
    Filed: April 18, 2006
    Publication date: September 3, 2009
    Inventors: Herve Groux, Francoise Cottrez, Herve Bastian