Patents by Inventor Hervé Prats

Hervé Prats has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method For Expressing Polypeptides In Eukaryotic Cells Using Alternative Splicing
    Publication number: 20090305343
    Abstract: This invention relates to an expression cassette for expressing polypeptides in eukaryotic cells using alternative splicing. The expression cassette comprises in 5? to 3? downstream direction: a promoter; a sequence transcribed in a 5? untranslated region (5?UTR); a donor splice site; an intron; a first acceptor splice site; a first cistron encoding a first polypeptide; a second acceptor splice site; a second cistron encoding a second polypeptide; an internal ribosome entry site (IRES) operably linked to a selection marker; and a sequence transcribed in a 3? untranslated region (3?UTR) including a polyadenylation signal, wherein the polyadenylation signal is unique.
    Type: Application
    Filed: May 16, 2007
    Publication date: December 10, 2009
    Applicants: MILLEGEN, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
    Inventors: Stéphanie Fallot, Abdelhakim Kharrat, Philippe Mondon, Khalil Bouayadi, Patrick Brune, Hervé Prats, Christian Touriol
  • Intraocular transplantation of encapsulated cells
    Patent number: 6663894
    Abstract: Compositions and methods for reducing ocular diseases by implanting in an eye of a subject a composition comprising encapsulated cells which produce polypeptides, more particularly polypeptides that exhibit neurotrophic and/or anti-angiogenic activity. The encapsulation prevents the entry of host immune cells in the microcapsule while permitting the release of the polypeptide outside of the microcapsule.
    Type: Grant
    Filed: February 1, 2001
    Date of Patent: December 16, 2003
    Assignees: Universite de Paris V Rene-Descartes, Association Francaise Retinitis Pigmentosa
    Inventors: Marc Abitbol, Yves Uteza, Maurice Menasche, Carine Bossard, Loic Van Den Berghe, Sebastian Bonnel, Hervé Prats, Jiri Honiger, Martin Neuner-Jehle
  • Intraocular transplantation of encapsulated cells
    Patent number: 6500449
    Abstract: Compositions and methods for reducing ocular diseases by implanting in an eye of a subject a composition comprising encapsulated cells which produce polypeptides, more particularly polypeptides that exhibit neurotrophic and/or anti-angiogenic activity. The encapsulation prevents the entry of host immune cells in the microcapsule while permitting the release of the polypeptide outside of the microcapsule.
    Type: Grant
    Filed: February 1, 2001
    Date of Patent: December 31, 2002
    Assignees: Universite de Paris V Rene-Descartes, Association Francaise Retinitis Pigmentosa
    Inventors: Marc Abitbol, Yves Uteza, Maurice Menasche, Carine Bossard, Loïc Van Den Berghe, Sébastian Bonnel, Hervé Prats, Jiri Honiger, Martin Neuner-Jehle
  • Intraocular transplantation of encapsulated cells
    Patent number: 6267954
    Abstract: Compositions and methods for reducing ocular diseases by implanting in an eye of a subject a composition encapsulated cells which produce polypeptides, more particularly polypeptides that exhibit neurotrophic and/or anti-anglogenic activity. The encapsulation prevents the entry of host immune cells in the microcapsule while permitting the release of the polypeptide outside of the microcapsule.
    Type: Grant
    Filed: November 24, 1999
    Date of Patent: July 31, 2001
    Assignees: Universite de Paris V Rene-Descartes, Association Francaise Retinitis Pigmentosa
    Inventors: Marc Abitbol, Yves Uteza, Maurice Menasche, Carine Bossard, Loïc Van Den Berghe, Sébastien Bonnel, Hervé Prats, Jiri Honiger, Martin Neuner-Jehle