Patents by Inventor Herve Groux

Herve Groux has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130005602
    Abstract: The invention relates to a method for evaluating the sensitizing potential of a test compound, and to a kit for implementing said method.
    Type: Application
    Filed: March 7, 2011
    Publication date: January 3, 2013
    Applicant: IMMUNOSEARCH
    Inventors: Herve Groux, Francoise Cottrez
  • Patent number: 7799328
    Abstract: The present invention relates to a method of treating or preventing weight loss of patients with inflammatory bowel diseases comprising administering to said patients an effective amount of Saccharomyces boulardii.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: September 21, 2010
    Assignee: Biocodex
    Inventors: Bernard Hublot, Herve Groux, Rene Levy, Marie-Emmanuelle Le Guern, Paul Bernasconi
  • Publication number: 20090221070
    Abstract: A method for the in vitro production of a cell population P? from a cell population P, the production requiring the presence of at least one factor which is expressed by feeder cells, wherein a) feeder cells proliferate at a temperature T1, b) proliferated feeder cells are contacted with the cell population P, c) the cell mixture obtained at step (b) is cultivated at a temperature T2 which is chosen such that the cell population P proliferates and the feeder cells do not proliferate, the at least one factor being expressed by the feeder cells, and d) the cell population P? so produced is recovered. Advantageously, the production consists in an expansion, the feeder cells are insect feeder cells and the cell population P to be expanded is a T lymphocyte population, preferably a Trl lymphocyte population.
    Type: Application
    Filed: April 18, 2006
    Publication date: September 3, 2009
    Inventors: Herve Groux, Francoise Cottrez, Herve Bastian
  • Publication number: 20090075372
    Abstract: An in vitro method for the obtention of a food- or auto-antigen specific Tr1 cell population from a leukocyte or a PBMC population, includes stimulating the PBMC or leukocyte population with the food- or auto-antigen, and recovering the food- or auto-antigen specific Tr1 cell population from the stimulated cell population. Preferably, the PBMC or leukocyte population is re-stimulated at least once with the same antigen after step (1), in the presence of IL-2 and at least one interleukin selected from the group consisting of IL-4 and IL-13. The in vitro method may further include a third step of expanding the recovered antigen-specific Tr1 cell population, advantageously by contacting them with feeder cells capable of expressing factors necessary for the expansion. Preferably, the feeder cells are recombinant insect feeder cells.
    Type: Application
    Filed: July 3, 2006
    Publication date: March 19, 2009
    Applicant: INSERM (INSTITUT NATIONAL DE LA SANTE DE LA RECHERCHE MEDICALE
    Inventors: Herve Groux, Francoise Cottrez
  • Publication number: 20080233095
    Abstract: The invention relates to a method for preparing antigen-specific Tr1 regulatory lymphocytes. The inventive method involves the use of artificial antigen-presenting cells, expressing a molecule from the HLA class II system and a human LFA-3 molecule and expressing none of the B7-1, B7-2, B7-H1, CD40, CD23 or ICAM-1 costimulation molecules.
    Type: Application
    Filed: October 30, 2007
    Publication date: September 25, 2008
    Applicant: INSTITUT NATIONAL DE LA SANTE DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Herve GROUX, Francoise Cottrez, Abdelilah Wakkach
  • Publication number: 20080107663
    Abstract: The present invention relates to a method of treating or preventing atherosclerosis comprising administering to a mammal in need of such a treatment a) an antigen which has been used to activate in vitro a Tri cell population originating from said mammal, and b) the TO cell population activated by said antigen, said TO cell population being obtained from a CD4+ T lymphocyte population of said mammal.
    Type: Application
    Filed: August 11, 2004
    Publication date: May 8, 2008
    Applicants: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), TXCELL
    Inventors: Herve Groux, Alain Tedgui, Ziad Mallat, Valerie Brun
  • Publication number: 20070275005
    Abstract: The present invention relates to the use of a method of treating or preventing a disease selected from the group of skin and diseases of the mucosa, comprising administering topically to a mammal in need of such a treatment a topical medicinal product comprising a lipopeptide or a mixture thereof, wherein said lipopeptide comprises a peptide antigen specific for a T cell population, said peptide antigen being coupled covalently with a lipid radical and being capable of activating the T cell population. Such a use is more specifically intended for a transcutaneous application of the topical medicinal product, which is advantageously intended to prevent or treat a skin disease. The invention also relates to pharmaceutical or cosmetic formulations comprising the lipopeptide according to the invention.
    Type: Application
    Filed: November 5, 2004
    Publication date: November 29, 2007
    Inventors: Herve Groux, Valerie Brun, Arnaud Foussat
  • Publication number: 20060140973
    Abstract: The present invention relates to a method of treating or preventing weight loss of patients with inflammatory bowel diseases comprising administering to said patients an effective amount of Saccharomyces boulardii.
    Type: Application
    Filed: December 23, 2004
    Publication date: June 29, 2006
    Inventors: Bernard Hublot, Herve Groux, Rene Levy, Marie-Emmanuelle Le Guern, Paul Bernasconi
  • Publication number: 20040191235
    Abstract: The invention relates to a method for preparing antigen-specific Tr1 regulatory lymphocytes. The inventive method involves the use of artificial antigen-presenting cells, expressing a molecule from the HLA class II system and a human LFA-3 molecule and expressing none of the B7-1, B7-2, B7-H1, CD40, CD23 or ICAM-1 costimulation molecules.
    Type: Application
    Filed: June 1, 2004
    Publication date: September 30, 2004
    Inventors: Herve Groux, Francoise Cottrez, Abdelilah Wakkach