Patents by Inventor Heshan Peiris

Heshan Peiris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Uridine Phosphorylase (UPase) Inhibitors for Treatment of Liver Conditions
    Publication number: 20230255971
    Abstract: Methods of treating a subject for a liver condition, e.g., NAFLD, NASH, and/or DILI, are provided. Aspects of the methods include administering to the subject an effective amount of a UPase inhibitor, optionally in combination with a uridine active agent (e.g., uridine (UR), a UR pro-drug or a UR mimetic), such as supplemental uridine, to treat the subject for the liver condition. Also provided are compositions for use in practicing the subject methods.
    Type: Application
    Filed: August 12, 2022
    Publication date: August 17, 2023
    Inventors: William A. Garland, Heshan Peiris, Philip Liaw, Brian D. Frenzel
  • Uridine phosphorylase (UPase) inhibitors for treatment of liver conditions
    Patent number: 11446303
    Abstract: Methods of treating a subject for a liver condition, e.g., NAFLD, NASH, and/or DILI, are provided. Aspects of the methods include administering to the subject an effective amount of a UPase inhibitor, optionally in combination with a uridine active agent (e.g., uridine (UR), a UR pro-drug or a UR mimetic), such as supplemental uridine, to treat the subject for the liver condition. Also provided are compositions for use in practicing the subject methods.
    Type: Grant
    Filed: June 17, 2020
    Date of Patent: September 20, 2022
    Assignee: Tosk, Inc.
    Inventors: William A. Garland, Heshan Peiris, Philip Liaw, Brian D. Frenzel
  • Uridine Phosphorylase (UPase) Inhibitors for Treatment of Liver Conditions
    Publication number: 20200397790
    Abstract: Methods of treating a subject for a liver condition, e.g., NAFLD, NASH, and/or DILI, are provided. Aspects of the methods include administering to the subject an effective amount of a UPase inhibitor, optionally in combination with a uridine active agent (e.g., uridine (UR), a UR pro-drug or a UR mimetic), such as supplemental uridine, to treat the subject for the liver condition. Also provided are compositions for use in practicing the subject methods.
    Type: Application
    Filed: June 17, 2020
    Publication date: December 24, 2020
    Inventors: William A. Garland, Heshan Peiris, Philip Liaw, Brian D. Frenzel