Patents by Inventor Hetal Pandya
Hetal Pandya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11976101Abstract: A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13R?2 binding ligand; at least one effector molecule (e.g., one, two, three or more effector molecules); optionally but preferably, a cytosol localization element covalently coupled between said binding ligand and said at least one effector molecule; and a subcellular compartment localization signal element covalently coupled between said binding ligand and said at least one effector molecule (and preferably with said cytosol localization element between said binding ligand and said subcellular compartment localization signal element). Methods of using such compounds and formulations containing the same are also described.Type: GrantFiled: September 2, 2021Date of Patent: May 7, 2024Assignee: Wake Forest University Health SciencesInventors: Waldemar Debinski, Hetal Pandya, Denise Gibo
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Publication number: 20210395324Abstract: A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13R?2 binding ligand; at least one effector molecule (e.g., one, two, three or more effector molecules); optionally but preferably, a cytosol localization element covalently coupled between said binding ligand and said at least one effector molecule; and a subcellular compartment localization signal element covalently coupled between said binding ligand and said at least one effector molecule (and preferably with said cytosol localization element between said binding ligand and said subcellular compartment localization signal element). Methods of using such compounds and formulations containing the same are also described.Type: ApplicationFiled: September 2, 2021Publication date: December 23, 2021Inventors: Waldemar Debinski, Hetal Pandya, Denise Gibo
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Patent number: 11136367Abstract: A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13R?2 binding ligand; at least one effector molecule (e.g., one, two, three or more effector molecules); optionally but preferably, a cytosol localization element covalently coupled between said binding ligand and said at least one effector molecule; and a subcellular compartment localization signal element covalently coupled between said binding ligand and said at least one effector molecule (and preferably with said cytosol localization element between said binding ligand and said subcellular compartment localization signal element). Methods of using such compounds and formulations containing the same are also described.Type: GrantFiled: December 5, 2019Date of Patent: October 5, 2021Assignee: Wake Forest University Health SciencesInventors: Waldemar Debinski, Hetal Pandya, Denise Gibo
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Publication number: 20200095302Abstract: A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13R?2 binding ligand; at least one effector molecule (e.g., one, two, three or more effector molecules); optionally but preferably, a cytosol localization element covalently coupled between said binding ligand and said at least one effector molecule; and a subcellular compartment localization signal element covalently coupled between said binding ligand and said at least one effector molecule (and preferably with said cytosol localization element between said binding ligand and said subcellular compartment localization signal element). Methods of using such compounds and formulations containing the same are also described.Type: ApplicationFiled: December 5, 2019Publication date: March 26, 2020Inventors: Waldemar Debinski, Hetal Pandya, Denise Gibo
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Patent number: 10519210Abstract: A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13R?2 binding ligand; at least one effector molecule (e.g., one, two, three or more effector molecules); optionally but preferably, a cytosol localization element covalently coupled between said binding ligand and said at least one effector molecule; and a subcellular compartment localization signal element covalently coupled between said binding ligand and said at least one effector molecule (and preferably with said cytosol localization element between said binding ligand and said subcellular compartment localization signal element). Methods of using such compounds and formulations containing the same are also described.Type: GrantFiled: January 30, 2019Date of Patent: December 31, 2019Assignee: Wake Forest University Health SciencesInventors: Waldemar Debinski, Hetal Pandya, Denise Gibo
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Publication number: 20190153057Abstract: A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13R?2 binding ligand; at least one effector molecule (e.g., one, two, three or more effector molecules); optionally but preferably, a cytosol localization element covalently coupled between said binding ligand and said at least one effector molecule; and a subcellular compartment localization signal element covalently coupled between said binding ligand and said at least one effector molecule (and preferably with said cytosol localization element between said binding ligand and said subcellular compartment localization signal element). Methods of using such compounds and formulations containing the same are also described.Type: ApplicationFiled: January 30, 2019Publication date: May 23, 2019Inventors: WALDEMAR DEBINSKI, HETAL PANDYA, DENISE GIBO
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Patent number: 10233224Abstract: A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13R?2 binding ligand; at least one effector molecule (e.g., one, two, three or more effector molecules); optionally but preferably, a cytosol localization element covalently coupled between said binding ligand and said at least one effector molecule; and a subcellular compartment localization signal element covalently coupled between said binding ligand and said at least one effector molecule (and preferably with said cytosol localization element between said binding ligand and said subcellular compartment localization signal element). Methods of using such compounds and formulations containing the same are also described.Type: GrantFiled: September 5, 2017Date of Patent: March 19, 2019Assignee: WAKE FOREST UNIVERSITY HEALTH SCIENCESInventors: Waldemar Debinski, Hetal Pandya, Denise Gibo
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Patent number: 9878013Abstract: A targeting peptide that specifically binds to an IL13 receptor (e.g., wherein said targeting peptide is not an IL13 fragment) is described. The targeting peptide is optionally conjugated to at least one effector molecule. In some embodiments, the peptide specifically binds to the IL13R?2 protein.Type: GrantFiled: February 17, 2016Date of Patent: January 30, 2018Assignee: Wake Forest University Health SciencesInventors: Waldemar Debinski, Hetal Pandya, Denise Mazess Herpai
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Publication number: 20180002394Abstract: A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13R?2 binding ligand; at least one effector molecule (e.g., one, two, three or more effector molecules); optionally but preferably, a cytosol localization element covalently coupled between said binding ligand and said at least one effector molecule; and a subcellular compartment localization signal element covalently coupled between said binding ligand and said at least one effector molecule (and preferably with said cytosol localization element between said binding ligand and said subcellular compartment localization signal element). Methods of using such compounds and formulations containing the same are also described.Type: ApplicationFiled: September 5, 2017Publication date: January 4, 2018Inventors: Waldemar Debinski, Hetal Pandya, Denise Gibo
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Patent number: 9771404Abstract: A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13R?2 binding ligand; at least one effector molecule (e.g., one, two, three or more effector molecules); optionally but preferably, a cytosol localization element covalently coupled between said binding ligand and said at least one effector molecule; and a subcellular compartment localization signal element covalently coupled between said binding ligand and said at least one effector molecule (and preferably with said cytosol localization element between said binding ligand and said subcellular compartment localization signal element). Methods of using such compounds and formulations containing the same are also described.Type: GrantFiled: April 8, 2015Date of Patent: September 26, 2017Assignee: Wake Forest University Health SciencesInventors: Waldemar Debinski, Hetal Pandya, Denise Gibo
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Publication number: 20160175399Abstract: A targeting peptide that specifically binds to an IL13 receptor (e.g., wherein said targeting peptide is not an IL13 fragment) is described. The targeting peptide is optionally conjugated to at least one effector molecule. In some embodiments, the peptide specifically binds to the IL13R?2 protein.Type: ApplicationFiled: February 17, 2016Publication date: June 23, 2016Inventors: Waldemar Debinski, Hetal Pandya, Denise Mazess Herpai
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Patent number: 9296785Abstract: A targeting peptide that specifically binds to an IL13 receptor (e.g., wherein said targeting peptide is not an IL13 fragment) is described. The targeting peptide is optionally conjugated to at least one effector molecule. In some embodiments, the peptide specifically binds to the IL13R?2 protein.Type: GrantFiled: April 16, 2010Date of Patent: March 29, 2016Assignee: Wake Forest University Health SciencesInventors: Waldemar Debinski, Hetal Pandya, Denise Gibo
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Publication number: 20150203557Abstract: A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13R?2 binding ligand; at least one effector molecule (e.g., one, two, three or more effector molecules); optionally but preferably, a cytosol localization element covalently coupled between said binding ligand and said at least one effector molecule; and a subcellular compartment localization signal element covalently coupled between said binding ligand and said at least one effector molecule (and preferably with said cytosol localization element between said binding ligand and said subcellular compartment localization signal element). Methods of using such compounds and formulations containing the same are also described.Type: ApplicationFiled: April 8, 2015Publication date: July 23, 2015Inventors: Waldemar Debinski, Hetal Pandya, Denise Gibo
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Patent number: 9005600Abstract: A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13R?2 binding ligand; at least one effector molecule (e.g., one, two, three or more effector molecules); optionally but preferably, a cytosol localization element covalently coupled between said binding ligand and said at least one effector molecule; and a subcellular compartment localization signal element covalently coupled between said binding ligand and said at least one effector molecule (and preferably with said cytosol localization element between said binding ligand and said subcellular compartment localization signal element). Methods of using such compounds and formulations containing the same are also described.Type: GrantFiled: December 18, 2012Date of Patent: April 14, 2015Assignee: Wake Forest University Health SciencesInventors: Waldemar Debinski, Hetal Pandya, Denise Gibo
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Patent number: 8929883Abstract: A system, method and software application track call failures on a wireless phone. A software application on the phone monitors outbound calls made on the phone to determine whether or not a call fails. In one embodiment, such monitoring is done only for a select period of time (e.g., the initial few seconds when the phone is attempting to connect to a call to the wireless communication carrier's network), and, in an alternate embodiment, such monitoring is done for the duration of the call. If a call fails, the software application stores information related to the call. Examples of such types of information include the time the call failed, the location of the phone at call failure, and identification information for the phone. The stored call information is then sent to the wireless communication carrier to enable the carrier to assess network quality.Type: GrantFiled: November 26, 2012Date of Patent: January 6, 2015Assignee: Nuance Communications, Inc.Inventors: Assaf Baciu, Hetal Pandya, Kevin Stone, David Winarsky
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Publication number: 20130246524Abstract: Provided is a method for sending event-triggered messages and gifts to network users, the message being generated by a triggering event. In one embodiment, meaningful events that are associated with a social network connection of a user are used as the triggering events. The method may comprise monitoring one or more events associated with one or more user connections in one or more social networks, identifying the events, generating the one or more connection-related actionable items, presenting the one or more connection-related actionable items to the user, receiving a user request to execute the one or more connection related items, and executing the one or more connection-related actionable items. Additionally, the user may be able to purchase one or more gifts and attach the one or more gift cards to messages sent to the one or more connections.Type: ApplicationFiled: March 16, 2012Publication date: September 19, 2013Inventors: Mikael Berner, Kavita Gaitonde, Edgar Kalns, Jon Landis, Kesava Neeli, Hetal Pandya
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Publication number: 20130209541Abstract: A targeting peptide that specifically binds to an IL13 receptor (e.g., wherein said targeting peptide is not an IL13 fragment) is described. The targeting peptide is optionally conjugated to at least one effector molecule. In some embodiments, the peptide specifically binds to the IL13R?2 protein.Type: ApplicationFiled: April 16, 2010Publication date: August 15, 2013Inventors: Waldemar Debinski, Hetal Pandya, Denise Gibo
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Patent number: 8362207Abstract: A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13R?2 binding ligand; at least one effector molecule (e.g., one, two, three or more effector molecules); optionally but preferably, a cytosol localization element covalently coupled between said binding ligand and said at least one effector molecule; and a subcellular compartment localization signal element covalently coupled between said binding ligand and said at least one effector molecule (and preferably with said cytosol localization element between said binding ligand and said subcellular compartment localization signal element). Methods of using such compounds and formulations containing the same are also described.Type: GrantFiled: April 14, 2011Date of Patent: January 29, 2013Assignee: Wake Forest University Health SciencesInventors: Waldemar Debinski, Hetal Pandya, Denise Gibo
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Patent number: 8331919Abstract: A system, method and software application track call failures on a wireless phone. A software application on the phone monitors outbound calls made on the phone to determine whether or not a call fails. In one embodiment, such monitoring is done only for a select period of time (e.g., the initial few seconds when the phone is attempting to connect to a call to the wireless communication carrier's network), and, in an alternate embodiment, such monitoring is done for the duration of the call. If a call fails, the software application stores information related to the call. Examples of such types of information include the time the call failed, the location of the phone at call failure, and identification information for the phone. The stored call information is then sent to the wireless communication carrier to enable the carrier to assess network quality.Type: GrantFiled: April 24, 2009Date of Patent: December 11, 2012Assignee: Nuance Communications, Inc.Inventors: Assaf Baciu, Hetal Pandya, Kevin M. Stone, David A. Winarsky
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Publication number: 20110300099Abstract: A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13R?2 binding ligand; at least one effector molecule (e.g., one, two, three or more effector molecules); optionally but preferably, a cytosol localization element covalently coupled between said binding ligand and said at least one effector molecule; and a subcellular compartment localization signal element covalently coupled between said binding ligand and said at least one effector molecule (and preferably with said cytosol localization element between said binding ligand and said subcellular compartment localization signal element). Methods of using such compounds and formulations containing the same are also described.Type: ApplicationFiled: April 14, 2011Publication date: December 8, 2011Inventors: WALDEMAR DEBINSKI, HETAL PANDYA, DENISE GIBO