Patents by Inventor Heung-Shick Lee
Heung-Shick Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20090170170Abstract: The present invention relates to the use of nucleic acid sequences for regulating the transcription and expression of genes, the novel promoters and expression units themselves, methods for altering or causing the transcription rate and/or expression rate of genes, expression cassettes comprising the expression units, genetically modified microorganisms with altered or caused transcription rate and/or expression rate, and methods for preparing biosynthetic products by cultivating the genetically modified microorganisms.Type: ApplicationFiled: July 16, 2005Publication date: July 2, 2009Applicant: BASF AktiengesellschaftInventors: Jong-Soo Choi, Weol Kyu Jeong, Il Kwon Kim, Seong Han Lim, Heung-Shick Lee
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Patent number: 7510854Abstract: Isolated nucleic acid molecules, designated MP nucleic acid molecules, which encode novel MP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated MP proteins, mutated MP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of MP genes in this organism.Type: GrantFiled: September 28, 2005Date of Patent: March 31, 2009Assignee: Evonik Degussa GmbHInventors: Markus Pompejus, Burkhard Kröger, Hartwig Schröder, Oskar Zelder, Gregor Haberhauer, Jun-Won Kim, Heung Shick-Lee, Byung-Joon Hwang
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Publication number: 20090004745Abstract: The present invention relates to the use of nucleic acid sequences for regulating the transcription and expression of genes, the novel promoters and expression units themselves, methods for altering or causing the transcription rate and/or expression rate of genes, expression cassettes comprising the expression units, genetically modified microorganisms with altered or caused transcription rate and/or expression rate, and methods for preparing biosynthetic products by cultivating the genetically modified microorganisms.Type: ApplicationFiled: July 16, 2005Publication date: January 1, 2009Applicant: BASF AktiengesellschaftInventors: Jong-Soo Choi, Weol Kyu Jeong, Il Kwon Kim, Seong Han Lim, Heung-Shick Lee
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Publication number: 20080318286Abstract: The present invention relates to the use of nucleic acid sequences for regulating the transcription and expression of genes, the novel promoters and expression units themselves, methods for altering or causing the transcription rate and/or expression rate of genes, expression cassettes comprising the expression units, genetically modified microorganisms with altered or caused transcription rate and/or expression rate, and methods for preparing biosynthetic products by cultivating the genetically modified microorganisms.Type: ApplicationFiled: July 16, 2005Publication date: December 25, 2008Applicant: BASF AktiengesellschaftInventors: Jong-Soo Choi, Weol Kyu Jeong, II Kwon Kim, Seong Han Lim, Heung-Shick Lee
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Publication number: 20080280333Abstract: Isolated polypeptide sequence having the sequence of SEQ ID NO:1 or muteins thereof having the ability to bind cAMP and repress the expression of the aceB gene of C. glutamicum and which can be obtained from SEQ ID NO:1 by inserting, deleting or substituting up to 20% of the amino acids.Type: ApplicationFiled: February 8, 2007Publication date: November 13, 2008Applicant: BASF AGInventors: Corinna Klopprogge, Oskar Zelder, Burkhard Kroger, Hartwig Schroder, Stefan Hafner, Heung-Shick Lee
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Publication number: 20070231867Abstract: The present invention relates to the use of nucleic acid sequences for regulating the transcription and expression of genes, the novel promoters and expression units themselves, methods for altering or causing the transcription rate and/or expression rate of genes, expression cassettes comprising the expression units, genetically modified microorganisms with altered or caused transcription rate and/or expression rate, and methods for preparing biosynthetic products by cultivating the genetically modified microorganisms.Type: ApplicationFiled: July 16, 2005Publication date: October 4, 2007Applicant: BASF AktiengesellschaftInventors: Jong-Soo Choi, Weol Jeong, Il Kim, Seong Lim, Heung-Shick Lee
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Publication number: 20070212711Abstract: The present invention relates to the use of nucleic acid sequences for regulating the transcription and expression of genes, the novel promoters and expression units themselves, methods for altering or causing the transcription rate and/or expression rate of genes, expression cassettes comprising the expression units, genetically modified microorganisms with altered or caused transcription rate and/or expression rate, and methods for preparing biosynthetic products by cultivating the genetically modified microorganisms.Type: ApplicationFiled: July 16, 2005Publication date: September 13, 2007Applicant: BASF AktiengesellschaftInventors: Jong-Soo Choi, Weol Jeong, Il Kim, Seong Lim, Heung-Shick Lee
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Publication number: 20070077576Abstract: Isolated nucleic acid molecules, designated SRT nucleic acid molecules, which encode novel SRT proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SRT nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated SRT proteins, mutated SRT proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of SRT genes in this organism.Type: ApplicationFiled: August 22, 2006Publication date: April 5, 2007Applicant: BASF AGInventors: Markus Pompejus, Burkhard Kroger, Hartwig Schroder, Oskar Zelder, Gregor Haberhauer, Heung-Shick Lee, Hyung-Joon Kim
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Patent number: 7192749Abstract: Isolated polypeptide sequence having the sequence of SEQ ID NO:1 or muteins thereof having the ability to bind cAMP and repress the expression of the aceB gene of C. glutamicum and which can be obtained from SEQ ID NO:1 by inserting, deleting or substituting up to 20% of the amino acids.Type: GrantFiled: May 13, 2003Date of Patent: March 20, 2007Assignee: BASF AktiengesellschaftInventors: Corinna Klopprogge, Oskar Zelder, Burkhard Kröger, Hartwig Schröder, Stefan Häfner, Heung-Shick Lee
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Publication number: 20070059810Abstract: Isolated nucleic acid molecules, designated SRT nucleic acid molecules, which encode novel SRT proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SRT nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated SRT proteins, mutated SRT proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of SRT genes in this organism.Type: ApplicationFiled: August 22, 2006Publication date: March 15, 2007Applicant: BASF AGInventors: Markus Pompejus, Burkhard Kroger, Hartwig Schroder, Oskar Zelder, Gregor Haberhauer, Heung-Shick Lee, Hyung-Joon Kim
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Publication number: 20060078884Abstract: Isolated nucleic acid molecules, designated SRT nucleic acid molecules, which encode novel SRT proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SRT nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated SRT proteins, mutated SRT proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of SRT genes in this organism.Type: ApplicationFiled: November 7, 2003Publication date: April 13, 2006Inventors: Markus Pompejus, Burkhard Kroger, Hartwig Schroder, Oskar Zelder, Gregor Haberhauer, Heung-Shick Lee, Hyung-Joon Kim
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Patent number: 6822084Abstract: Isolated nucleic acid molecules, designated SRT nucleic acid molecules, which encode novel SRT proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SRT nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated SRT proteins, mutated SRT proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of SRT genes in this organism.Type: GrantFiled: June 23, 2000Date of Patent: November 23, 2004Assignee: BASF AktiengesellschaftInventors: Markus Pompejus, Burkhard Kroger, Hartwig Schröder, Oskar Zelder, Gregor Haberhauer, Heung-Shick Lee, Hyung-Joon Kim
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Publication number: 20030049804Abstract: Isolated nucleic acid molecules, designated MP nucleic acid molecules, which encode novel MP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated MP proteins, mutated MP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicurn based on genetic engineering of MP genes in this organism.Type: ApplicationFiled: December 22, 2000Publication date: March 13, 2003Inventors: Markus Pompejus, Burkhard Kroger, Hartwig Schroder, Oskar Zelder, Gregor Haberhauer, Jun-Won Kim, Heung-Shick Lee, Byung-Joon Hwang