Patents by Inventor Hexin Chen

Hexin Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MiRNA-489 in treatment of breast cancer
    Patent number: 10053696
    Abstract: Breast cancer treatment methods and materials incorporating microRNA-489 are described. The methods and materials have been developed from identification of a double-negative feedback loop between miR-489 and the HER2-SHP2-MAPK signaling axis. The methods and materials may be particularly beneficial in treatment and diagnosis of HER2 positive breast cancers.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: August 21, 2018
    Assignee: University of South Carolina
    Inventors: Hexin Chen, Yogin C. Patel, Nirav R. Shah
  • miRNA-489 IN TREATMENT OF BREAST CANCER
    Publication number: 20170211074
    Abstract: Breast cancer treatment methods and materials incorporating microRNA-489 are described. The methods and materials have been developed from identification of a double-negative feedback loop between miR-489 and the HER2-SHP2-MAPK signaling axis. The methods and materials may be particularly beneficial in treatment and diagnosis of HER2 positive breast cancers.
    Type: Application
    Filed: January 20, 2017
    Publication date: July 27, 2017
    Inventors: Hexin Chen, Yogin C. Patel, Nirav R. Shah
  • HOX COMPOSITIONS AND METHODS
    Publication number: 20130333059
    Abstract: The present invention relates to compositions to treat HOXB7 related disorders. The invention also relates to methods treating HOXB7 related disorders. The invention further relates to kits for treating HOXB7 related disorders in a subject. The invention further relates to methods of identifying novel treatments for treating HOXB7 related disorders in a subject.
    Type: Application
    Filed: September 26, 2012
    Publication date: December 12, 2013
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Saraswati Sukumar, Zhu Tao, Xinyan Wu, Hexin Chen
  • Hox Compositions and Methods
    Publication number: 20100285031
    Abstract: The present invention relates to compositions to treat HOXB7 related disorders. The invention also relates to methods treating HOXB7 related disorders. The invention further relates to kits for treating HOXB7 related disorders in a subject. The invention further relates to methods of identifying novel treatments for treating HOXB7 related disorders in a subject.
    Type: Application
    Filed: May 21, 2007
    Publication date: November 11, 2010
    Applicant: The Johns Hopkins University
    Inventors: Saraswati Sukumar, Zhu Tao, Xinyan Wu, Hexin Chen