Patents by Inventor Hexin SHI

Hexin SHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220072553
    Abstract: A device and a method for detecting tumor mutation burden (TMB) based on capture sequencing are disclosed. The device includes: a panel design module configured to uniformly add population single-nucleotide polymorphism (SNP) sites to a genome and screen out gene regions that show the highest consistency with whole exome sequencing (WES); a data acquisition module configured to acquire tissue and plasma samples of a target object and acquire sequencing data of the samples; an alignment module configured to align the sequencing data with a reference genome to acquire mutation data results; a somatic mutation analysis module configured to perform somatic analysis on the mutation data results to obtain somatic mutation results; a filtering module configured to remove unreal mutation sites from the somatic mutation results; and a calculation module configured to calculate the TMB.
    Type: Application
    Filed: March 16, 2021
    Publication date: March 10, 2022
    Applicant: ZHENYUE BIOTECHNOLOGY JIANGSU CO., LTD.
    Inventors: Hexin SHI, Jianing YU, Yuanyuan HONG, Minjun CHEN, Ying YANG, Junyan HOU, Hong LV, Weizhi CHEN, Shan ZHENG, Ji HE, Bo DU