Patents by Inventor Hi-Shi Chiang

Hi-Shi Chiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pulmonary administration of dry powder formulations for treating infertility
    Patent number: 7112341
    Abstract: Provided are stabilized follicle stimulating protein (FSP) dry powder compositions for aerosolized delivery to the deep lung, methods of preparing and administering such compositions, and methods for treating infertility involving administering the dry powders by pulmonary delivery to the deep lung.
    Type: Grant
    Filed: April 13, 2000
    Date of Patent: September 26, 2006
    Assignee: Nektar Therapeutics
    Inventors: Sudha Nagarajan, John S. Patton, David B. Bennett, Joanne Greene, Hi-Shi Chiang, Cheryl L. M. Stults, Geraldine Venthoye, Darrel LaVern Allen, Benjamin Lee Hughes, Mary Stiff-Torvik, Ronald Keith Wolff, William David Roeder
  • Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
    Publication number: 20050186143
    Abstract: The present invention provides highly dispersible spray-dried powder compositions, and in particular, inhaleable dry powder compositions for aerosolized delivery to the lungs. The powders of the invention are produced by spray drying a 4 ?-helix bundle protein under conditions which both (i) protect the protein from aggregation and (ii) provide particles suitable for inhalation (i.e., demonstrating superior aerosol performance).
    Type: Application
    Filed: November 17, 2004
    Publication date: August 25, 2005
    Applicant: Nektar Therapeutics
    Inventors: Cynthia Stevenson, Jayne Hastedt, S. Lehrman, Hi-Shi Chiang, David Bennett, David Lesikar, Bing Yang, David Gong, Kirsten Cabot
  • Use of proton sequestering agents in drug formulations
    Publication number: 20050013867
    Abstract: Methods are provided for preparing spray-dried, drug-containing particles comprising the steps of: (a) selecting drug, an aqueous solution, and a proton-sequestering agent; (b) adding the drug and the proton-sequestering agent to the solution to form a feed solution; and (c) spray drying the feed solution to form the spray-dried, drug-containing particles, wherein at least a portion of the proton-sequestering agent remains mixed with the drug in the spray-dried, drug containing particles, particles and pharmaceutical formulations comprising the prepared particles as well as methods of use are also provided.
    Type: Application
    Filed: October 16, 2002
    Publication date: January 20, 2005
    Inventors: S. Lehrman, Hi-Shi Chiang, Mei-Chang Kuo, Jiang Zhang, David Ballesteros
  • Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
    Patent number: 6838075
    Abstract: The present invention provides highly dispersible spray-dried powder compositions, and in particular, inhaleable dry powder compositions for aerosolized delivery to the lungs. The powders of the invention are produced by spray drying a 4 ?-helix bundle protein under conditions which both (i) protect the protein from aggregation and (ii) provide particles suitable for inhalation (i.e., demonstrating superior aerosol performance).
    Type: Grant
    Filed: March 14, 2003
    Date of Patent: January 4, 2005
    Assignee: Nektar Therapeutics
    Inventors: Cynthia Stevenson, Jayne E. Hastedt, Russ Lehrman, Hi-Shi Chiang, David B. Bennett, David Lesikar, Bing Yang, David Gong, Kirsten Cabot
  • Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
    Publication number: 20030190291
    Abstract: The present invention provides highly dispersible spray-dried powder compositions, and in particular, inhaleable dry powder compositions for aerosolized delivery to the lungs. The powders of the invention are produced by spray drying a 4 &agr;-helix bundle protein under conditions which both (i) protect the protein from aggregation and (ii) provide particles suitable for inhalation (i.e., demonstrating superior aerosol performance).
    Type: Application
    Filed: March 14, 2003
    Publication date: October 9, 2003
    Applicant: Nektar Therapeutics
    Inventors: Cynthia Stevenson, Jayne E. Hastedt, S. Russ Lehrman, Hi-Shi Chiang, David B. Bennett, David Lesikar, Bing Yang, David Gong, Kirsten Cabot
  • Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
    Patent number: 6569406
    Abstract: The present invention provides highly dispersible spray-dried powder compositions, and in particular, inhaleable dry powder compositions for aerosolized delivery to the lungs. The powders of the invention are produced by spray drying a 4 &agr;-helix bundle protein under conditions which both (i) protect the protein from aggregation and (ii) provide particles suitable for inhalation (i.e., demonstrating superior aerosol performance).
    Type: Grant
    Filed: August 7, 2001
    Date of Patent: May 27, 2003
    Assignee: Nektar Therapeutics
    Inventors: Cynthia Stevenson, Jayne E. Hastedt, S. Russ Lehrman, Hi-Shi Chiang, David B. Bennett, David Lesikar, Bing Yang, David Gong, Kirsten Cabot
  • Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
    Publication number: 20020065399
    Abstract: The present invention provides highly dispersible spray-dried powder compositions, and in particular, inhaleable dry powder compositions for aerosolized delivery to the lungs. The powders of the invention are produced by spray drying a 4 &agr;-helix bundle protein under conditions which both (i) protect the protein from aggregation and (ii) provide particles suitable for inhalation (i.e., demonstrating superior aerosol performance).
    Type: Application
    Filed: August 7, 2001
    Publication date: May 30, 2002
    Applicant: Inhale Therapeutic Systems, Inc.
    Inventors: Cynthia Stevenson, Jayne E. Hastedt, S. Russ Lehrman, Hi-Shi Chiang, David B. Bennett, David Lesikar, Bing Yang, David Gong, Kirsten Cabot