Patents by Inventor Hibrenigus Terefe

Hibrenigus Terefe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for enhancing the solubility of poorly soluble drugs
    Patent number: 7607596
    Abstract: The solubility/dissolution rate of a poorly soluble drug is enhanced by a process that utilizes a twin-screw extruder containing (i) a feed zone containing a first liquid and powder feed stations; (ii) a grinding/mixing zone containing a second liquid feed port located at an upstream portion of such zone; (iii) a granulation zone containing a second powder feed station located at an upstream portion of such zone and a third liquid feed port located at a downstream portion of such zone; and (iv) a wet milling zone.
    Type: Grant
    Filed: February 25, 2008
    Date of Patent: October 27, 2009
    Assignee: Exxpharma, LLC
    Inventors: Isaac Ghebre-Sellassie, Hibrenigus Terefe