Patents by Inventor Hicham NAIMY

Hicham NAIMY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MANNOSE-6-PHOSPHATE BEARING PEPTIDES FUSED TO LYSOSOMAL ENZYMES
    Publication number: 20200376095
    Abstract: A targeted therapeutic including a lysosomal enzyme and a lysosomal targeting moiety that is a peptide containing at least one N-linked glycosylation site. Methods of producing the targeted therapeutic may include nucleotide acids encoding the same and host cells co-expressing GNPT. Pharmaceutical compositions comprising the targeted therapeutic and methods of using the same to treat a lysosomal storage disease.
    Type: Application
    Filed: June 18, 2020
    Publication date: December 3, 2020
    Inventors: Michael F. CONCINO, Bettina STRACK-LOGUE, Muthuraman MEIYAPPAN, Angela W. NORTON, Bohong ZHANG, Andrea ISKENDERIAN, Lieh Yoon LOW, Dianna LUNDBERG, Alla ROMASHKO, Hicham NAIMY
  • Mannose-6-phosphate bearing peptides fused to lysosomal enzymes
    Patent number: 10722559
    Abstract: A targeted therapeutic including a lysosomal enzyme and a lysosomal targeting moiety that is a peptide containing at least one N-linked glycosylation site. Methods of producing the targeted therapeutic may include nucleotide acids encoding the same and host cells co-expressing GNPT. Pharmaceutical compositions comprising the targeted therapeutic and methods of using the same to treat a lysosomal storage disease.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: July 28, 2020
    Assignee: Shire Human Genetic Therapies, Inc.
    Inventors: Michael F. Concino, Bettina Strack-Logue, Muthuraman Meiyappan, Angela W. Norton, Bohong Zhang, Andrea Iskenderian, Lieh Yoon Low, Dianna Lundberg, Alla Romashko, Hicham Naimy
  • Determination of glycosaminoglycan levels by mass spectrometry
    Patent number: 10578624
    Abstract: Detecting glycosaminoglycans (GAGs) and/or determining the level of one or more glycosaminoglycans can be useful, e.g., in identifying or monitoring various medical conditions, the status of patients having various medical conditions, and/or the response to treatment of individuals having various medical conditions. The present invention provides methods for detecting glycosaminoglycans and/or determining the level of glycosaminoglycans through the use of, e.g., mass spectrometry.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: March 3, 2020
    Assignee: Shire Human Genetic Therapies, Inc.
    Inventors: Hicham Naimy, Yongchang Qiu, Patrick Anthony John Haslett, Ann Barbier
  • DETERMINATION OF GLYCOSAMINOGLYCAN LEVELS BY MASS SPECTROMETRY
    Publication number: 20170350900
    Abstract: Detecting glycosaminoglycans (GAGs) and/or determining the level of one or more glycosaminoglycans can be useful, e.g., in identifying or monitoring various medical conditions, the status of patients having various medical conditions, and/or the response to treatment of individuals having various medical conditions. The present invention provides methods for detecting glycosaminoglycans and/or determining the level of glycosaminoglycans through the use of, e.g., mass spectrometry.
    Type: Application
    Filed: November 13, 2015
    Publication date: December 7, 2017
    Inventors: Hicham NAIMY, Yongchang QIU, Patrick Anthony John HASLETT, Ann BARBIER
  • MANNOSE-6-PHOSPHATE BEARING PEPTIDES FUSED TO LYSOSOMAL ENZYMES
    Publication number: 20170232076
    Abstract: A targeted therapeutic including a lysosomal enzyme and a lysosomal targeting moiety that is a peptide containing at least one N-linked glycosylation site. Methods of producing the targeted therapeutic may include nucleotide acids encoding the same and host cells co-expressing GNPT. Pharmaceutical compositions comprising the targeted therapeutic and methods of using the same to treat a lysosomal storage disease.
    Type: Application
    Filed: August 11, 2015
    Publication date: August 17, 2017
    Inventors: Michael F. CONCINO, Bettina STRACK-LOGUE, Muthuraman MEIYAPPAN, Angela W. NORTON, Bohong ZHANG, Andrea ISKENDERIAN, Lieh Yoon LOW, Dianna LUNDBERG, Alla ROMASHKO, Hicham NAIMY