Abstract: A separation membrane element including a pair of separation membranes containing two separation membranes arranged so that the filtrate-side surfaces thereof are disposed in mutually opposed relation, and a plurality of resin members bonded to both of the mutually opposed filtrate-side surfaces, a peripheral edge of the pair of separation membranes being sealed.

Abstract: In a waste water treatment method using membrane separation-activated sludge, when, during filtration while supplying air using an immersion-type membrane separation unit loaded with multiple flexible membranes, the filtration differential pressure of the membranes at a set filtration flow rate exceeds a specified value P2 with respect to the filtration differential pressure P1 of the initial period of operation, membrane filtration is continued with air supply stopped until the filtration differential pressure P3 becomes P3?P1+20 [kPa]. Then with the filtration flux or filtration pressure being smaller or negative compared to when filtering while supplying air, air is supplied and after the filtration differential pressure P4 during filtration reaches P4?P1+5 [kPa], filtration is returned to filtration while supplying air.

Abstract: In a waste water treatment method using membrane separation-activated sludge, when, during filtration while supplying air using an immersion-type membrane separation unit loaded with multiple flexible membranes, the filtration differential pressure of the membranes at a set filtration flow rate exceeds a specified value P2 with respect to the filtration differential pressure P1 of the initial period of operation, membrane filtration is continued with air supply stopped until the filtration differential pressure P3 becomes P3?P1+20 [kPa]. Then with the filtration flux or filtration pressure being smaller or negative compared to when filtering while supplying air, air is supplied and after the filtration differential pressure P4 during filtration reaches P4?P1+5 [kPa], filtration is returned to filtration while supplying air.

Abstract: A separation-membrane module 1 includes an element block 2 that is formed by arranging, in parallel, a plurality of separation-membrane elements 4 that are formed by arranging a pair of separation-membranes with their respective permeate surfaces in opposition to each other and sealing the edges of the pair of the membranes; and an aeration block 3 that includes an aeration pipe 31 and that is disposed under the element block 2. In the element block 2, at least one upper spacer 8 is disposed in the upper portion of each space between the adjacent separation-membrane elements 4, and a lower spacer 9 is disposed under the upper spacer 8 in each space between the adjacent separation-membrane elements 4. And the leftmost and the rightmost separation-membrane elements 4 of the plurality of the separation-membrane elements 4 are secured to a frame 12 at the lower spacers 9.

Abstract: A separation-membrane module 1 includes an element block 2 that is formed by arranging, in parallel, a plurality of separation-membrane elements 4 that are formed by arranging a pair of separation-membranes with their respective permeate surfaces in opposition to each other and sealing the edges of the pair of the membranes; and an aeration block 3 that includes an aeration pipe 31 and that is disposed under the element block 2. In the element block 2, at least one upper spacer 8 is disposed in the upper portion of each space between the adjacent separation-membrane elements 4, and a lower spacer 9 is disposed under the upper spacer 8 in each space between the adjacent separation-membrane elements 4. And the leftmost and the rightmost separation-membrane elements 4 of the plurality of the separation-membrane elements 4 are secured to a frame 12 at the lower spacers 9.

Abstract: A separation membrane module has an element unit. The element unit includes: a shaft; a plurality of separation membrane elements each including a separation membrane pair having two separation membranes disposed so that permeate-side surfaces of the separation membranes face each other and a water collecting flow path provided between the separation membranes, and a sealed portion that seals the separation membranes at peripheral edge portions of the separation membranes; a suspension portion that suspends the separation membrane elements on the shaft; and a water collection nozzle provides communication between the water collection flow path and an outside of the separation membrane elements.

Abstract: A separation membrane element including a pair of separation membranes containing two separation membranes arranged so that the filtrate-side surfaces thereof are disposed in mutually opposed relation, and a plurality of resin members bonded to both of the mutually opposed filtrate-side surfaces, a peripheral edge of the pair of separation membranes being sealed.

Abstract: A fuel filter device is provided in which a filter assembly having filter layers of first multiple layers is provided in a fuel flow path extending from the interior of a fuel tank to fuel consumption means via a fuel pump, and the finest filter layer is disposed downstream-most in filter layers of second multiple layers forming at least part of the first multiple layers, wherein an aggregation-promoting part (24A) that promotes aggregation of dust in fuel by changing the flow direction or flow velocity of fuel is provided in the filter assembly (20A) so that aggregation of dust in fuel is promoted before the upstream side of at least the second finest filter layer (22A) of the filter layers (21A, 22A, 23A) among the second multiple layers. This enables the durability of the fuel filter device to be improved.

Abstract: The present invention provides a composition comprising an IP3 receptor-binding protein (IRBIT), a nucleic acid that controls the expression and translation of IRBIT, or an antibody against IRBIT for controlling at least one intracellular biological function selected from the group consisting of (1) protein synthesis, (2) phosphatidylinositol metabolism, and (3) intracellular pH.

Abstract: The present invention provides a composition comprising an IP3 receptor-binding protein (IRBIT), a nucleic acid that controls the expression and translation of IRBIT, or an antibody against IRBIT for controlling at least one intracellular biological function selected from the group consisting of (1) protein synthesis, (2) phosphatidylinositol metabolism, and (3) intracellular pH.

Abstract: Analysis of substance capable of binding with inositol-1,4,5-triphosphate (IP3) receptor (IP3R), preferably with a regulation domain of IP3R; analysis of the function of IP3R; and establishing of a method of treatment or diagnosis for various malfunctions and diseases associated with IP3R. In particular, control of the activity of intracellular Ca2+ release. More specifically, a regulator for the activity of inositol-1,4,5-triphosphate (IP3) receptor (IP3R), comprised of carbonic anhydrase related protein (CARP); a control agent for intracellular calcium release, comprised of carbonic anhydrase related protein (CARP); and a method of control therewith.

Abstract: Analysis of substance capable of binding with inositol-1,4,5-triphosphate (IP3) receptor (IP3R), preferably with a regulation domain of IP3R; analysis of the function of IP3R; and establishing of a method of treatment or diagnosis for various malfunctions and diseases associated with IP3R. In particular, control of the activity of intracellular Ca2+ release. More specifically, a regulator for the activity of inositol-1,4,5-triphosphate (IP3) receptor (IP3R), comprised of carbonic anhydrase related protein (CARP); a control agent for intracellular calcium release, comprised of carbonic anhydrase related protein (CARP); and a method of control therewith.

Abstract: Analysis of substance capable of binding with inositol-1, 4,5-triphosphate (IP3) receptor (IP3R), preferably with a regulation domain of IP3R; analysis of the function of IP3R; and establishing of a method of treatment or diagnosis for various malfunctions and diseases associated with IP3R. In particular, control of the activity of intracellular Ca2+ release. More specifically, a regulator for the activity of inositol-1,4, 5-triphosphate (IP3) receptor (IP3R), comprised of carbonic anhydrase related protein (CARP); a control agent for intracellular calsium release, comprised of carbonic anhydrase related protein (CARP); and a method of control therewith.

Abstract: Analysis of substance capable of binding with inositol-1,4,5-triphosphate (IP3) receptor (IP3R), preferably with a regulation domain of IP3R; analysis of the function of IP3R; and establishing of a method of treatment or diagnosis for various malfunctions and diseases associated with IP3R. In particular, control of the activity of intracellular Ca2+ release. More specifically, a regulator for the activity of inositol-1,4,5-triphosphate (IP3) receptor (IP3R), comprised of carbonic anhydrase related protein (CARP); a control agent for intracellular calsium release, comprised of carbonic anhydrase related protein (CARP); and a method of control therewith.

Abstract: The present invention provides a novel IP3 receptor-binding protein that is used as an indicator effective for detecting and quantifying IP3, and a method for detecting and/or quantifying IP3 using the same. Determined is an IP3 receptor-binding protein, particularly a novel IP3 receptor-binding protein, IRBIT, which interacts with an IP3 receptor, and whose interaction is regulated by IP3. IRBIT has the characteristic that it can be dissociated from the IP3 receptor by IP3 at a physiological concentration. Because of this characteristic, IRBIT can be useful as an indicator for detecting IP3 by the FRET method or the like.

Abstract: An improved data comparison circuit for comparing two pieces of data having 12 bits is disclosed. In the data comparison circuit, cell circuits compare two pieces of data for every corresponding 4 bits. When a match is detected in the comparison of a set of 4 bits, a signal representative of the comparison result of the lower-order bits is bypassed. That is, by bypassing a signal representative of the comparison result of the lower order bits through the cell circuit in which the match is detected, the delay of signal propagation which may occur in the cell circuit in which the match is detected can be prevented.