Patents by Inventor Hideaki Mizuno
Hideaki Mizuno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220153875Abstract: An objective of the present invention is to provide antigen-binding molecules whose antigen-binding activity changes depending on the concentration of a small molecule compound specific to a target tissue, polynucleotides encoding the antigen-binding molecules, vectors containing the polynucleotides, cells carrying the vectors, libraries containing a plurality of the antigen-binding molecules that are different from one another, pharmaceutical compositions containing the antigen-binding molecules, methods of screening for the antigen-binding molecules, methods of producing the same, and the like.Type: ApplicationFiled: March 19, 2020Publication date: May 19, 2022Applicant: Chugai Seiyaku Kabushiki KaishaInventors: Hideaki Mizuno, Koichiro Saka, Hiroki Kawauchi, Kuniyasu Kato, Ryoichi Saito, Tomoyuki Igawa, Kazuhiro Ohara, Junya Okude
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Patent number: 10707505Abstract: A cathode gas cooling system provided with a heat exchanger having first internal channels into which cathode gas flows and second internal channels to which water discharged from a fuel cell is supplied and cooling cathode gas flowing through the first internal channels by latent heat of vaporization of water flowing through the second internal channels. The first internal channels and second internal channel are are respectively made independent channels inside the heat exchanger so that steam produced inside the second internal channels by heat exchange with cathode gas flowing through the first internal channels does not flow into the first internal channels.Type: GrantFiled: March 23, 2018Date of Patent: July 7, 2020Assignee: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Yuya Kusano, Hideaki Mizuno
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Publication number: 20180277869Abstract: A cathode gas cooling system provided with a heat exchanger having first internal channels into which cathode gas flows and second internal channels to which water discharged from a fuel cell is supplied and cooling cathode gas flowing through the first internal channels by latent heat of vaporization of water flowing through the second internal channels. The first internal channels and second internal channel are are respectively made independent channels inside the heat exchanger so that steam produced inside the second internal channels by heat exchange with cathode gas flowing through the first internal channels does not flow into the first internal channels.Type: ApplicationFiled: March 23, 2018Publication date: September 27, 2018Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Yuya Kusano, Hideaki Mizuno
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Publication number: 20170274728Abstract: A motor-driven compressor is installed in a fuel cell vehicle to supply air to a fuel cell. The motor driven compressor includes a rotation shaft, an electric motor, a compression unit that compresses air, a housing that includes a motor chamber and a compression chamber, and a seal member that restricts a flow of a fluid between the motor chamber and the compression chamber. The housing includes an inlet and an outlet. The inlet draws, into the motor chamber, the air-conditioning refrigerant that has passed through the evaporator but has not reached the air-conditioning compressor as a low-temperature refrigerant. The outlet discharges the low-temperature refrigerant, which is drawn from the inlet into the motor chamber, out of the motor chamber.Type: ApplicationFiled: March 20, 2017Publication date: September 28, 2017Applicants: KABUSHIKI KAISHA TOYOTA JIDOSHOKKI, TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Junya SUZUKI, Rei MORINAGA, Hideaki MIZUNO
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Patent number: 9490494Abstract: If a required voltage which corresponds to a required power has reached a boundary voltage, which is an oxidation-reduction potential of platinum, which constitutes a catalyst of a fuel cell, the fuel cell system performs crossover-avoidance control that holds an FC instruction voltage for the fuel cell at the boundary voltage, and absorbs the gap between the required voltage and the FC instruction voltage by using a secondary battery.Type: GrantFiled: May 7, 2012Date of Patent: November 8, 2016Assignee: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Yuji Kakeno, Hideaki Mizuno, Kenji Umayahara, Yoshiaki Naganuma, Masashi Toida
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Patent number: 9260009Abstract: A hydrogen tank is mounted on a roof so that a valve unit mounted to one end in a longitudinal direction of the hydrogen tank is separated as far apart as possible from a front platform and a middle platform of a fuel cell equipped bus and so that the longitudinal direction of the hydrogen tank is in a lateral direction of a vehicle. Thus, even if hydrogen leaks from the valve unit or a fusible plug valve of the valve unit is fused to discharge hydrogen from the tank, the influence of the leaking or discharged hydrogen on the front platform and the middle platform can be reduced.Type: GrantFiled: January 6, 2006Date of Patent: February 16, 2016Assignee: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Hideaki Mizuno, Yoshiaki Naganuma
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Publication number: 20150325896Abstract: If a required voltage which corresponds to a required power has reached a boundary voltage, which is an oxidation-reduction potential of platinum, which constitutes a catalyst of a fuel cell, the fuel cell system performs crossover-avoidance control that holds an FC instruction voltage for the fuel cell at the boundary voltage, and absorbs the gap between the required voltage and the FC instruction voltage by using a secondary battery.Type: ApplicationFiled: May 7, 2012Publication date: November 12, 2015Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Yuji KAKENO, Hideaki MIZUNO, Kenji UMAYAHARA, Yoshiaki NAGANUMA, Masashi TOIDA
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Publication number: 20150322398Abstract: A biomass treatment device and a biomass treatment method, in which contamination is prevented and a final product can be highly concentrated. The biomass treatment device includes a pretreatment device for pretreating a biomass, a slurrying device for slurrying the pretreated biomass, and a saccharification device for saccharifying the slurried biomass with a saccharifying enzyme. A return line for returning a part of an internal fluid in the saccharification device to the slurrying device is provided, and the pretreated biomass from the pretreatment device and the internal fluid returned through the return line are mixed in the slurrying device so as to generate biomass slurry.Type: ApplicationFiled: March 27, 2013Publication date: November 12, 2015Inventors: Tomoki HAYAKAWA, Hideaki MIZUNO
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Publication number: 20140009487Abstract: According to embodiments, an image processing device is disclosed. The image processing device comprises a memory unit configured to store a foreground image data and a background image data, a data transfer unit configured to transmit image data from the memory unit, and an image data processing unit configured to process image data. The image data processing unit comprises a subsampling designation unit configured to instruct the memory section to transmit over the data transfer unit a subsampled image data, the subsampled image data being subsampled from the background image data stored in the memory unit. The image data processing unit further comprises a transparency processing unit configured to perform transparency processing on the foreground image data to form a transparent image data.Type: ApplicationFiled: March 4, 2013Publication date: January 9, 2014Applicant: Kabushiki Kaisha ToshibaInventor: Hideaki MIZUNO
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Publication number: 20130255619Abstract: A bonding method includes bonding a pair of members together made of conductive material and having bonding surfaces which are not positioned on the same plane. In the bonding method, the bonding surfaces of the members to be bonded are positioned to face each other, an electric current is supplied from one of the members to be bonded to the other for carrying out resistance heating while the pair of members to be bonded are slid relative to each other. In this way, the bonding surfaces are bonded to each other. Split or partition surfaces that form a hollow passage and extending along the axis of the hollow passage are set as the bonding surfaces which are not on the same plane.Type: ApplicationFiled: December 9, 2011Publication date: October 3, 2013Applicant: NISSAN MOTOR CO., LTD.Inventors: Hideaki Mizuno, Toru Fukami, Kenshi Ushijima
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Publication number: 20130092662Abstract: Joining surfaces (2a, 2b) of a pair of conductive joining members (1a, 1b) to be joined to each other are caused to face each other, and while one of the joining members (1a, 1b) is slid relative to the other of the joining members (1a, 1b), a current is passed from one of the joining members (1a, 1b) to the other of the joining members (1a, 1b) so as to cause resistance heating. Abrasion, plastic flow, and material diffusion therefore occur in high surface-pressure sections of the joining surfaces (2a, 2b), and the joining surfaces (2a, 2b) are joined together while current concentration locations are varied from moment to moment.Type: ApplicationFiled: June 23, 2011Publication date: April 18, 2013Inventors: Toru Fukami, Kenshi Ushijima, Masahiko Kondo, Hideaki Mizuno, Katsuya Moteki
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Patent number: 8349124Abstract: A sealing material for a honeycomb structure includes inorganic fibers, oxide sol, and inorganic particles. The inorganic fibers include at least one of an alkali metal compound, an alkaline earth metal compound and a boron compound. The sealing material has a pH of at least about 4 and at most about 6.Type: GrantFiled: December 12, 2008Date of Patent: January 8, 2013Assignee: Ibiden Co., Ltd.Inventors: Hideaki Mizuno, Akikazu Miyata, Yosuke Fuchi
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Patent number: 8216734Abstract: Provided is a fuel cell system which can properly control a refresh operation. A controller controls the refresh operation so that an output voltage does not exceed an avoidance voltage even after the refresh operation. Specifically, the controller estimates the output voltage after the refresh operation from the output voltage before the refresh operation and controls execution of the refresh operation so that the estimated output voltage after the refresh operation does not exceed the avoidance voltage. For example, if before the refresh operation, when judging that the estimated output voltage after the refresh operation does not exceed the avoidance voltage, the controller executes the refresh operation.Type: GrantFiled: January 15, 2009Date of Patent: July 10, 2012Assignee: Toyota Jidosha Kabushiki KaishaInventor: Hideaki Mizuno
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Patent number: 8110311Abstract: There is provided a fuel cell system capable of warming up a fuel cell while inhibiting generation of a rush current. A control device switches the connection/disconnection between a fuel cell and a short circuit by a shorting relay. The control device spends, before switching the shorting relay from disconnection to connection during starting at a low temperature, an oxidizing gas remaining in the cathode of the fuel cell by driving auxiliary devices to generate an oxidizing gas-deficient state. Then, the control device switches FC relays from ON to OFF and the shorting relay from OFF to ON to thereby complete the preparation for supplying a short-circuit current.Type: GrantFiled: November 20, 2006Date of Patent: February 7, 2012Assignee: Toyota Jidosha Kabushiki KaishaInventors: Kota Manabe, Kimihide Horio, Hideaki Mizuno, Hironori Noto, Takashi Yamamoto, Tomoya Ogawa
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Patent number: 8034614Abstract: The object of the present invention is to provide a novel fluorescent protein in which on and off of fluorescence thereof can be controlled by irradiation with lights of two different wavelengths. The present invention provides a fluorescent protein shown in the following (a) or (b); (a) a protein which has the amino acid sequence shown in SEQ ID NO: 3 or 7; or (b) a protein which has an amino acid sequence comprising a deletion, substitution, and/or addition of one or several amino acids with respect to the amino acid sequence shown in SEQ ID NO: 3 or 7, and which has fluorescence characteristics of exhibiting a photochromic effect.Type: GrantFiled: January 18, 2011Date of Patent: October 11, 2011Assignee: RikenInventors: Atsushi Miyawaki, Ryoko Ando, Hideaki Mizuno, Satoshi Karasawa
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Patent number: 8017276Abstract: An output limitation warning lamp is turned on when a possible output Qf of the fuel cell is less than a predetermined value L2. The output limitation warning lamp is provided at a combination meter in an instrument panel. The output limitation warning lamp is also turned on when a possible output Qb of the secondary battery is less than a predetermined value L3. Furthermore, the output limitation warning lamp is also turned on when an allowable drive output Qh, which is the sum of the possible output Qf of the fuel cell and the possible output Qb of the secondary battery, has been less than a required output Ed* calculated at a step before carrying out output limitation to more than a certain extent for longer than a predetermined length of time.Type: GrantFiled: March 2, 2007Date of Patent: September 13, 2011Assignee: Toyota Jidosha Kabushiki KaishaInventors: Tatsuya Fujita, Yasuhiko Niimi, Takashi Kotoh, Hideaki Mizuno, Nobuo Watanabe, Tadaichi Matsumoto
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Patent number: 8012637Abstract: An output limitation warning lamp is turned on when a possible output Qf of the fuel cell is less than a predetermined value L2. The output limitation warning lamp is provided at a combination meter in an instrument panel. The output limitation warning lamp is also turned on when a possible output Qb of the secondary battery is less than a predetermined value L3. Furthermore, the output limitation warning lamp is also turned on when an allowable drive output Qh, which is the sum of the possible output Qf of the fuel cell and the possible output Qb of the secondary battery, has been less than a required output Ed* calculated at a step before carrying out output limitation to more than a certain extent for longer than a predetermined length of time.Type: GrantFiled: June 17, 2002Date of Patent: September 6, 2011Assignee: Toyota Jidosha Kabushiki KaishaInventors: Tatsuya Fujita, Yasuhiko Niimi, Takashi Kotoh, Hideaki Mizuno, Nobuo Watanabe, Tadaichi Matsumoto
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Patent number: 8011343Abstract: A multi link type piston-crank mechanism comprises an upper link that has one end pivotally connected to a piston of the engine through a piston pin, a lower link that is pivotally connected to the other end of the upper link through an upper pin and rotatably disposed on a crank pin of a crankshaft of the engine; and a control link that has a base end part swingably held by a body of the engine and a leading end pivotally connected to the lower link through a control pin. An axis of the piston pin is offset relative to an axis of the piston in thrust and counter thrust directions. When the piston comes to BDC, a part of the piston takes a position below a lower edge of a corresponding cylinder of the engine and the upper pin is offset relative to the axis of the piston pin in the same direction as a pin offset direction in which the axis of the piston pin is offset in the thrust and counter thrust directions relative to the axis of the piston.Type: GrantFiled: July 31, 2008Date of Patent: September 6, 2011Assignee: Nissan Motor Co., Ltd.Inventors: Makoto Kobayashi, Kenshi Ushijima, Hideaki Mizuno, Naoki Takahashi
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Patent number: 7981558Abstract: A fuel cell system comprises a fuel cell, a supply flow passage for flowing a fuel gas supplied from a fuel supply source to the fuel cell, a variable gas supply device for regulating the state of the gas on the upstream side of the supply flow passage to supply the gas to the downstream side, a discharge flow passage for flowing a fuel off gas discharged from the fuel cell, a discharge valve for discharging the gas from the discharge flow passage to the exterior, and a control part for closing the discharge valve when the discharge amount of the gas calculated while the discharge valve is opened exceeds a predetermined target discharge amount. The control part stops the gas supply from the variable gas supply device and simultaneously closes the discharge valve, when the discharge amount of the gas calculated while the discharge valve is opened exceeds the target discharge amount.Type: GrantFiled: June 5, 2007Date of Patent: July 19, 2011Assignee: Toyota Jidosha Kabushiki KaishaInventors: Katsuki Ishigaki, Hideaki Mizuno
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Publication number: 20110152502Abstract: The object of the present invention is to provide a novel fluorescent protein in which on and off of fluorescence thereof can be controlled by irradiation with lights of two different wavelengths. The present invention provides a fluorescent protein shown in the following (a) or (b); (a) a protein which has the amino acid sequence shown in SEQ ID NO: 3 or 7; or (b) a protein which has an amino acid sequence comprising a deletion, substitution, and/or addition of one or several amino acids with respect to the amino acid sequence shown in SEQ ID NO: 3 or 7, and which has fluorescence characteristics of exhibiting a photochromic effect.Type: ApplicationFiled: January 18, 2011Publication date: June 23, 2011Applicant: RIKENInventors: Atsushi MIYAWAKI, Ryoko ANDO, Hideaki MIZUNO, Satoshi KARASAWA