Patents by Inventor Hidefumi Yamakawa

Hidefumi Yamakawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antineoplastic agent-entrapping liposomes
    Patent number: 4906477
    Abstract: Some of antineoplastic agents, for instance, adriamycin and daunorubicin, have a positive charge at physiological pH. Such drugs possess high affinity for binding to steroidal sulfate by means of electrostatic force. The invention utilizes this property to prepare steroidal sulfate liposomes having a net negative charge and encapsulating the antineoplastic agent.
    Type: Grant
    Filed: February 8, 1988
    Date of Patent: March 6, 1990
    Assignee: Kabushiki Kaisha Vitamin Kenkyusyo
    Inventors: Masayasu Kurono, Hitoshi Noda, Tomio Ogasawara, Hidefumi Yamakawa, Takafumi Iida, Kunio Yagi