Patents by Inventor Hideharu Ishida

Hideharu Ishida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8148505
    Abstract: An ?-selective glycosylation process of a glycosylation reaction between a sugar structure of hexose or an aldose having a chain with six or more carbon atoms in the molecule, which is a monosaccharide or a reducing end of an oligosaccharide with two or more monosaccharide residues connected by glycosidic linkages (an oligosaccharide with two monosaccharide residues is disaccharide) (also referred to as “a disaccharide to an oligosaccharide”) or a sugar chain and alcoholic hydroxyl group or thiol group, to obtain a sugar structure glycoside containing ?-glycoside at a high ratio, under the ring-shaped formation of a protective group in a silyl acetal structure over hydroxyl groups at positions 4 and 6 in the sugar structure. By the process, highly selective ?-glycosylation of sugar structure can be progressed in a simple and efficient manner.
    Type: Grant
    Filed: May 19, 2004
    Date of Patent: April 3, 2012
    Assignee: Japan Science and Technology Agency
    Inventors: Hiromune Ando, Akihiro Imamura, Makoto Kiso, Hideharu Ishida
  • Publication number: 20110286937
    Abstract: The present invention provides a glycolipid-containing liposome. In such a glycolipid-containing liposome, the glycolipid includes a plant ceramide portion and a sugar chain portion. The present invention also provides a method of producing a glycolipid-containing liposome. This method includes the following steps of: A) providing a glycolipid in which the glycolipid includes a plant ceramide portion and a sugar chain portion; and B) mixing the provided glycolipid with a liposome raw material and subjecting the mixture to conditions in which a liposome is formed.
    Type: Application
    Filed: February 18, 2009
    Publication date: November 24, 2011
    Applicants: GIFU UNIVERSITY, KATAYAMA CHEMICAL INDUSTRIES CO., LTD.
    Inventors: Makoto Kiso, Hideharu Ishida, Taiji Yamashita, Koichi Igarashi, Masahiko Hirai
  • Publication number: 20060122379
    Abstract: an ?-selective glycosylation process of a glycosylation reaction between a sugar structure of hexose or an aldose having a chain with six or more carbon atoms in the molecuse, which is a monosaccharide or a reducing end of an oligosaccharide with two or more monosaccharide residues connected by glycosidic linkages (an oligosaccharide with two monosaccharide residues is disaccharide) (also referred to as “a disaccharide to an oligosaccharide”) or a sugar chain and alcoholic hydroxyl group of thiol group, to obtain a sugar structure glycoside containing ?-glycoside at a high ratio, under the ring-shaped formation of a protective group in a silyl acetal structure over hydroxyl groups at positions 4 and 6 in the sugar structure. By the process, highly selective ?-glycosylation of sugar structure can be progressed in a simple and efficient manner.
    Type: Application
    Filed: May 19, 2004
    Publication date: June 8, 2006
    Inventors: Hiromune Ando, Akihiro Imamura, Makoto Kiso, Hideharu Ishida
  • Patent number: 6503885
    Abstract: Carboxymethylgalactose derivatives represented by general formula (1); and salts thereof, which exhibit reactivity to selectins and are useful as inhibitors against selectin-related diseases such as various inflammations and cancerous metastasis; In said formula, R is a group rep resented by formula (1a), (1b) or (1c).
    Type: Grant
    Filed: March 20, 2001
    Date of Patent: January 7, 2003
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Makoto Kiso, Hideharu Ishida
  • Patent number: 5589465
    Abstract: Novel glycolipid derivatives of Formula (I): ##STR1## wherein R is a long chain alkyl, or their salts are disclosed. These compounds act as a ligand for selectin family and exhibit a remarkable inhibitory effect on the binding of selectin family to its native ligand sialyl Lewis.sup.x.
    Type: Grant
    Filed: March 1, 1995
    Date of Patent: December 31, 1996
    Assignees: Akira Hasegawa, Kanebo Ltd.
    Inventors: Hideharu Ishida, Makoto Kiso, Akira Hasegawa
  • Patent number: 5093970
    Abstract: This invention provides a lead-acid battery plate and its manufacturing method. In a lead-acid battery plate making use of an expanded metal comprising copper or copper alloy electroplated with lead or lead alloy for its grid; this invention is characterized by that a protector is provided on a side of the grid. And in a manufacturing method for a lead acid battery plate in which the expanded metal comprising copper or copper alloy electroplated with lead or lead alloy is used for its grid, and a plate lug comprising lead or lead alloy is connected by casting to an upper part of the grid; this invention is characterized by that the plate lug is first connected by casting to the upper part of the copper expanded metal, and lead or lead alloy is then electroplated on the copper expanded metal to which the plate lug is connected.
    Type: Grant
    Filed: April 30, 1990
    Date of Patent: March 10, 1992
    Inventors: Keiji Senoo, Takamasa Yoshida, Hideharu Ishida, Masao Takura