Patents by Inventor Hidehiko Matsukawa

Hidehiko Matsukawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biphenyl derivatives and drug composition
    Patent number: 6225306
    Abstract: A biphenyl derivative represented by the following general formula (1) and a pharmaceutically acceptable salt thereof: [In the formula (1), A represents a single bond, —CH2—, —CO—, —CS— or —SO2—; B represents a single bond or —CH2—; R1 represents a hydrogen atom, —OH, —NR11R12 (wherein R11 and R12 each independently represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms), —OCOCH3, or a halogen atom; R2 represents a hydrogen atom or R1 and R2 form a group ═O together; R3 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; provided that in the formula, the absolute configuration of the position a may be either R or S]. The compound of the present invention has considerably high safety and efficacy and is useful as, in particular, a vasopressin receptor antagonist.
    Type: Grant
    Filed: September 30, 1999
    Date of Patent: May 1, 2001
    Assignee: Wakamoto Pharmaceutical Co., Ltd.
    Inventors: Yasuhiro Ohtake, Akira Naito, Kenji Naito, Hidehiko Matsukawa, Yoshiaki Saito, Hatsunori Toyofuku