Patents by Inventor Hidehiko Oka

Hidehiko Oka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-Hydroxy-2-pyrone derivatives having antihyperlipaemic activity
    Patent number: 4255444
    Abstract: 4-Hydroxy-2-pyrone derivatives of formula (I): ##STR1## (wherein A represents an alkylene group which is optionally alkyl-substituted or an alkenylene group, and Z represents a substituted or unsubstituted aryl or aryloxy group) may be prepared by cyclizing an ester of formula (II): ##STR2## (wherein A and Z are as defined above and R represents an organic group) and have valuable antilipaemic activities.
    Type: Grant
    Filed: October 26, 1979
    Date of Patent: March 10, 1981
    Assignee: Sankyo Company Limited
    Inventors: Hidehiko Oka, Akira Terahara, Akira Endo
  • 3,5-Dihydroxypentanoic ester derivatives having antihyperlipaemic activity
    Patent number: 4248889
    Abstract: 3,5-Dihydroxypentanoic ester derivatives of formula (I): ##STR1## wherein: A represents an alkylene group which is optionally substituted by one or more alkyl groups, or an alkenylene group;Z represents a substituted or unsubstituted aryl or aryloxy group; andR represents a C.sub.1 -C.sub.4 alkyl group) may be prepared by reacting a dianion of an acetoacetic ester with an aldehyde of formula Z-A-CHO (wherein A and Z are as defined above) and then reducing the resulting compound. These 3,5-dihydroxypentanoic ester derivatives have antihyperlipaemic activity and are thus valuable pharmaceuticals.
    Type: Grant
    Filed: October 26, 1979
    Date of Patent: February 3, 1981
    Assignee: Sankyo Company Limited
    Inventors: Hidehiko Oka, Akira Terahara, Akira Endo