Patents by Inventor Hidehito Kuroyanagi

Hidehito Kuroyanagi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic reporter system that reveals expression profiles and regulation mechanisms of alternative splicing in nematodes
    Patent number: 7928283
    Abstract: An object of the present invention is to develop a new alternative splicing reporter system and to provide a method for detecting alternative splicing patterns in a multicellular organism more precisely, a method for identifying efficiently substances and gene regions that affect alternative splicing in a multicellular organism, and the like by utilizing the alternative splicing reporter system. Specifically, the present invention relates to a method for detecting alternative splicing in a multicellular organism, and a method for identifying substances and gene regions that affect alternative splicing in a multicellular organism, which use a DNA construct in which at least two different reporter genes are inserted into a specific gene that undergoes alternative splicing, or a combination of DNA constructs (a combination of at least two different DNA constructs) in which DNA construct a reporter gene is inserted into a specific gene that undergoes alternative splicing.
    Type: Grant
    Filed: September 26, 2007
    Date of Patent: April 19, 2011
    Assignee: Kinopharma, Inc.
    Inventors: Hidehito Kuroyanagi, Masatoshi Hagiwara
  • Transgenic reporter system that reveals expression profiles and regulation mechanisms of alternative splicing in living organisms
    Publication number: 20080095712
    Abstract: An object of the present invention is to develop a new alternative splicing reporter system and to provide a method for detecting alternative splicing patterns in a multicellular organism more precisely, a method for identifying efficiently substances and gene regions that affect alternative splicing in a multicellular organism, and the like by utilizing the alternative splicing reporter system. Specifically, the present invention relates to a method for detecting alternative splicing in a multicellular organism, and a method for identifying substances and gene regions that affect alternative splicing in a multicellular organism, which use a DNA construct in which at least two different reporter genes are inserted into a specific gene that undergoes alternative splicing, or a combination of DNA constructs (a combination of at least two different DNA constructs) in which DNA construct a reporter gene is inserted into a specific gene that undergoes alternative splicing.
    Type: Application
    Filed: September 26, 2007
    Publication date: April 24, 2008
    Inventors: Hidehito Kuroyanagi, Masatoshi Hagiwara