Abstract: A novel nitrogenous fused bicyclic compound represented by the following general formula [1] or a pharmacologically acceptable salt of the compound. They have excellent SK channel blocking activity and are useful as a medicine. [I] (In the formula, R0 represents hydrogen, halogeno, etc.; R1 represents a group represented by the formula (a) or (b); A represents a group represented by the formula (X) or (Y); D1, D2 and D3 each represents N or CH; R2 represents halogeno or optionally halogenated lower alkyl, etc.; R3 represents hydrogen or lower alkyl; and Q represents lower alkylene.

Abstract: The present relates to a spindle unit for a machine tool having a spindle rotatably held in a housing and a hydraulic tool holding system at a forward end of the spindle and capable of holding a tool on the spindle without a tool holder. The spindle of the spindle unit is provided with a tool receiving bore formed in the forward end portion of the spindle along the rotational axis thereof, one or more pressure chambers disposed around the tool receiving bore in spaced relationship from the tool receiving bore by a thin wall elastically deformable in a radial direction of the spindle, and a working fluid passage formed in the spindle and in fluid communication with the one or more pressure chambers. The spindle unit further includes a pressure adjusting device arranged in the rear portion of the spindle unit and connected to the pressure chamber through the working fluid passage.

Abstract: The present relates to a spindle unit for a machine tool having a spindle rotatably held in a housing and a hydraulic tool holding system at a forward end of the spindle and capable of holding a tool on the spindle without a tool holder. The spindle of the spindle unit is provided with a tool receiving bore formed in the forward end portion of the spindle along the rotational axis thereof, one or more pressure chambers disposed around the tool receiving bore in spaced relationship from the tool receiving bore by a thin wall elastically deformable in a radial direction of the spindle, and a working fluid passage formed in the spindle and in fluid communication with the one or more pressure chambers. The spindle unit further includes a pressure adjusting device arranged in the rear portion of the spindle unit and connected to the pressure chamber through the working fluid passage.

Abstract: The present relates to a spindle unit for a machine tool having a spindle rotatably held in a housing and a hydraulic tool holding system at a forward end of the spindle and capable of holding a tool on the spindle without a tool holder. The spindle of the spindle unit is provided with a tool receiving bore formed in the forward end portion of the spindle along the rotational axis thereof, one or more pressure chambers disposed around the tool receiving bore in spaced relationship from the tool receiving bore by a thin wall elastically deformable in a radial direction of the spindle, and a working fluid passage formed in the spindle and in fluid communication with the one or more pressure chambers. The spindle unit further includes a pressure adjusting device arranged in the rear portion of the spindle unit and connected to the pressure chamber through the working fluid passage.