Abstract: Provided are a method of refining a reaction solution including a carbonate of 1,5-diaminopentane, which is produced by fermentation, through a decarbonation step and a pH adjustment step, and 1,5-diaminopentane which is refined by the above method.

Abstract: Provided is a method for refining quinolinic acid, including the steps of: preparing a fermentation solution including at least one of quinolinic acid and a salt thereof; removing microbial cells from the fermentation solution; preparing an acidic composition containing at least one of quinolinic acid and a salt thereof at a saturation concentration or more by adding an acid to the fermentation solution; and recovering a crystal of least one of quinolinic acid and a salt thereof from the acidic composition.

Abstract: A suspension system for an engine includes an engine mount and an electronic control unit. The engine mount has spring characteristics that are switchable between first spring characteristics and second spring characteristics. The electronic control unit is configured to switch the spring characteristics of the engine mount to the first spring characteristics when the rotational speed of the engine is lower than a predetermined rotational speed, and torque of the engine is equal to or larger than a predetermined torque. The electronic control unit is configured to switch the spring characteristics of the engine mount to the second spring characteristics when the rotational speed of the engine is lower than the predetermined rotational speed, and the torque of the engine is smaller than the predetermined torque.

Abstract: A purification method of 1,4-diaminobutane, 1,4-diaminobutane purified using the purification method, and a polyamide prepared using the purified 1,4-diaminobutane are provided. The purification method of 1,4-diaminobutane includes: concentrating a fermentation solution including at least one of 1,4-diaminobutane and a salt thereof to obtain a concentrate; adding a base to the concentrate of the fermentation solution to prepare an basic composition having a pH 12 or higher; and recovering 1,4-diaminobutane from the basic composition.

Abstract: A configuration system, for a process control system configured to perform process control, the configuration system includes, not limited to, a) an editor configured to perform one of generate and update one of a definition module and an application module, wherein a set of the definition module and the application module comprises control logic and design data for a part of an industrial plant. The editor includes, not limited to, a-1) a definition module generator configured to generate or update one of a definition module control logic and an application module control logic based on the definition module design data. The editor is implemented by one or more processors.

Abstract: A configuration system for a process control system configured to perform process control. The configuration system includes, not limited to, a) a definition module, which is stored in a memory, for a part of an industrial plant based on design data. The definition module includes, not limited to, a-1) a control logic definition file configured to define a control logic for the part, and a-2) a data definition file configured to define data relating to the defined control logic.

Abstract: Provided is a method for refining quinolinic acid, including the steps of: preparing a fermentation solution including at least one of quinolinic acid and a salt thereof; removing microbial cells from the fermentation solution; preparing an acidic composition containing at least one of quinolinic acid and a salt thereof at a saturation concentration or more by adding an acid to the fermentation solution; and recovering a crystal of least one of quinolinic acid and a salt thereof from the acidic composition.

Abstract: A purification method of 1,4-diaminobutane, 1,4-diaminobutane purified using the purification method, and a polyamide prepared using the purified 1,4-diaminobutane are provided. The purification method of 1,4-diaminobutane includes: concentrating a fermentation solution including at least one of 1,4-diaminobutane and a salt thereof to obtain a concentrate; adding a base to the concentrate of the fermentation solution to prepare an basic composition having a pH 12 or higher; and recovering 1,4-diaminobutane from the basic composition.

Abstract: A method of purifying cytidine diphosphate choline, which comprises contacting a cytidine diphosphate choline solution containing a nucleic acid analogue and having a pH of not less than 0.5 and not more than 5.0 with an H-type strongly acidic cation exchange resin, and eluting cytidine diphosphate choline adsorbed onto the resin with water or an aqueous solution having an ion concentration of not more than 0.1 mol/L to separate and purify the cytidine diphosphate choline.

Abstract: Disclosed is a crystal of glutathione having an average width of 7 to 40 ?m and an average particle diameter of 10 to 60 ?m, preferably having an angle of repose of 53 degree or less, more preferably having a crude specific volume of 5.0 cm3/g or less, still more preferably in the form of an alpha-form crystal. Also disclosed is a tablet containing such a crystal of glutathione. Further disclosed is a process for producing such a crystal of glutathione.

Abstract: In the method for separating and purifying histidine from a culture containing the amino acid, the culture containing histidine and microbial cells is charged onto the top of a column filled with a carrier particle whose particle size is 420 ?m or more and which has an ability to adsorb histidine and then an eluent is passed through the column whereby accomplishing the separation and purification of histidine, and preferably in the step mentioned above, a strong acid cation exchange resin is employed as a carrier particle whereby accomplishing the separation and purification of histidine.

Abstract: The present invention provides crystals of L-ornithine and a process for producing the crystals of L-ornithine including the steps of (i) exposing L-ornithine or a salt thereof, a composition comprising L-ornithine or a salt thereof, or a solution containing L-ornithine, a salt thereof, or the composition to a cation exchange resin to adsorb L-ornithine onto the cation exchange resin; (ii) eluting L-ornithine from the cation exchange resin on which L-ornithine is adsorbed with an aqueous alkaline solution, and removing an alkaline component from the resulting eluate to prepare an aqueous L-ornithine solution; and (iii) mixing the aqueous L-ornithine solution with a hydrophilic organic solvent, and crystallizing L-ornithine from the resulting mixed solution.

Abstract: In the method for separating and purifying a basic amino acid, preferably the basic amino acid selected from arginine, lysine or ornithine from a culture containing the amino acid, the culture containing the a basic amino acid and microbial cells, preferably the culture whose pH is 4 to 10, is charged onto the top of a column filled with a weak acid cation exchange resin whose particle size is 300 ?m or more and passed therethrough, and then an eluent is poured into the column from the top thereof whereby accomplishing the separation and the purification of the basic amino acid.

Abstract: Disclosed is a crystal of glutathione having an average width of 7 to 40 ?m and an average particle diameter of 10 to 60 ?m, preferably having an angle of repose of 53 degree or less, more preferably having a crude specific volume of 5.0 cm3/g or less, still more preferably in the form of an alpha-form crystal. Also disclosed is a tablet containing such a crystal of glutathione. Further disclosed is a process for producing such a crystal of glutathione.

Abstract: A method of purifying cytidine diphosphate choline, which comprises contacting a cytidine diphosphate choline solution containing a nucleic acid analogue and having a pH of not less than 0.5 and not more than 5.0 with an H-type strongly acidic cation exchange resin, and eluting cytidine diphosphate choline adsorbed onto the resin with water or an aqueous solution having an ion concentration of not more than 0.1 mol/L to separate and purify the cytidine diphosphate choline.

Abstract: A partially purified product of a hyaluronic acid salt obtained from a culture of a microorganism capable of producing hyaluronic acid, preferably a microorganism belonging to the genus Streptcoccus, is brought into contact with a solution containing a salt and a hydrophilic organic solvent, thereby transferring to a liquid phase, impurities contained in said partially purified product such as proteins, nucleic acids, colorants, endotoxins and the like, and then isolating the hyaluronic acid salt as a precipitate.

Abstract: In the method for separating and purifying histidine from a culture containing the amino acid, the culture containing histidine and microbial cells is charged onto the top of a column filled with a carrier particle whose particle size is 350 ?m or more and which has an ability to adsorb histidine and then an eluent is passed through the column whereby accomplishing the separation and purification of histidine, and preferably in the step mentioned above, a strong acid cation exchange resin is employed as a carrier particle whereby accomplishing the separation and purification of histidine.

Abstract: The present invention provides crystals of L-ornithine and a process for producing the crystals of L-ornithine including the steps of (i) exposing L-ornithine or a salt thereof, a composition comprising L-ornithine or a salt thereof, or a solution containing L-ornithine, a salt thereof, or the composition to a cation exchange resin to adsorb L-ornithine onto the cation exchange resin; (ii) eluting L-ornithine from the cation exchange resin on which L-ornithine is adsorbed with an aqueous alkaline solution, and removing an alkaline component from the resulting eluate to prepare an aqueous L-ornithine solution; and (iii) mixing the aqueous L-ornithine solution with a hydrophilic organic solvent, and crystallizing L-ornithine from the resulting mixed solution.

Abstract: In the method for separating and purifying a basic amino acid, preferably the basic amino acid selected from arginine, lysine or ornithine from a culture containing the amino acid, the culture containing the a basic amino acid and microbial cells, preferably the culture whose pH is 4 to 10, is charged onto the top of a column filled with a weak acid cation exchange resin whose particle size is 300 ?m or more and passed therethrough, and then an eluent is poured into the column from the top thereof whereby accomplishing the separation and the purification of the basic amino acid.

Abstract: According to the present invention, a method of purifying ubiquinone-10, which includes separating and removing a substance structurally similar to ubiquinone-10 contained in a starting material solution containing ubiquinone-10 by the use of a porous crosslinked acrylic polymer, more preferably, a method of purifying ubiquinone-10 by separating and removing a substance structurally similar to ubiquinone-10 contained in a starting material solution, which includes feeding a starting material solution containing ubiquinone-10 in a simulated moving bed chromatography apparatus wherein a solution can circulate in one direction in a packed-bed wherein a porous crosslinked acrylic polymer is packed, and flowing an eluent in the packed-bed in one direction, is provided.