Abstract: An image forming apparatus includes an image reading unit, an original conveyance unit, a reversing unit, an image forming unit, an image forming conveyance unit, and a control unit. The original conveyance unit conveys an original in a first direction toward the image reading unit, which reads an image of the original. The reversing unit conveys an original passing through the image reading unit in the first direction, or reversely conveys the original toward the image reading unit in a second direction. The image forming unit forms an image on a sheet. The image forming conveyance unit conveys, to the image forming unit, an original reversely conveyed by the reversing unit via the image reading unit. The control unit controls an operation for reading an image of the original by using the image reading unit and for overprinting the original with an image by using the image forming unit.

Abstract: The present invention provides a fixing device including a flexible cylindrical rotary member and an inner-surface opposing portion that opposes an inner surface of the rotary member at an end portion of the rotary member in a generatrix direction. The inner-surface opposing portion moves upstream in a recording material conveying direction in accordance with lateral shift of the rotary member in the generatrix direction. This restricts the lateral shift of the rotary member.

Abstract: A fixing device includes a cylindrical film, a back-up member in contact with an inner surface of the film, a roller configured to form a fixing nip portion with the back-up member via the film, and a metal bearing configured to rotatably hold a shaft of the roller. The fixing device further includes an insulating portion provided between an end surface of the film and the bearing, thereby suppressing occurrence of leakage between the bearing and the end surface of the film.

Abstract: The present invention provides a fixing device including a flexible cylindrical rotary member and an inner-surface opposing portion that opposes an inner surface of the rotary member at an end portion of the rotary member in a generatrix direction. The inner-surface opposing portion moves upstream in a recording material conveying direction in accordance with lateral shift of the rotary member in the generatrix direction. This restricts the lateral shift of the rotary member.

Abstract: A fixing device includes first and second members, a frame supporting the second member, and two pressure mechanisms provided on either end of the first member. The mechanism includes a lever having one end supported by the frame in a rotatable manner in a pressure direction, and a helical compression spring disposed between a first spring support provided on the other end of the lever and a second spring support on the frame. At least one of the first and second spring supports includes a first area and a second area closer to the spring in the axial direction than the first area, the first area is in contact with an area of the spring close to a winding end of the spring, and the second area is in contact with an area of the spring farther away from the winding end in a winding direction than the first area.

Abstract: An image fixing apparatus includes: a heater for heating and fixing a toner image formed on a recording material; a thermosensitive element for sensing heat from the heater; and a tension spring for urging the thermosensitive element toward the heater.

Abstract: The present invention provides a fixing device including a flexible cylindrical rotary member and an inner-surface opposing portion that opposes an inner surface of the rotary member at an end portion of the rotary member in a generatrix direction. The inner-surface opposing portion moves upstream in a recording material conveying direction in accordance with lateral shift of the rotary member in the generatrix direction. This restricts the lateral shift of the rotary member.

Abstract: The present invention provides a fixing device including a flexible cylindrical rotary member and an inner-surface opposing portion that opposes an inner surface of the rotary member at an end portion of the rotary member in a generatrix direction. The inner-surface opposing portion moves upstream in a recording material conveying direction in accordance with lateral shift of the rotary member in the generatrix direction. This restricts the lateral shift of the rotary member.

Abstract: An image forming apparatus includes a sheet feed unit which feeds a sheet to an image forming unit forming an image on the sheet, a re-transport roller which reverses the sheet with a toner image fixed on the sheet and re-transports the sheet to the image forming unit, and a control unit which controls a sheet feed operation of the sheet feed unit for feeding the sheet. As the temperature of the re-transport roller sensed by the temperature sensing unit is decreased, the control unit retards the timing at which the sheet feed unit starts the sheet feed operation when a duplex image formation in which the image is formed on both sides of the sheet is performed after a one-side image formation is completed.

Abstract: A monoclonal antibody for detecting or capturing an exosome, selected from the group consisting of a monoclonal antibody or antibody fragments thereof that recognize amino acid numbers 113 to 195 of the amino acid sequence as shown in SEQ ID NO: 1, a monoclonal antibody or antibody fragments thereof that recognize amino acid numbers 104 to 202 of the amino acid sequence as shown in SEQ ID NO: 2, a monoclonal antibody or antibody fragments thereof that recognize amino acid numbers 36 to 54 of the amino acid sequence as shown in SEQ ID NO: 3, and a monoclonal antibody or antibody fragments thereof that recognize amino acid numbers 113 to 201 of the amino acid sequence as shown in SEQ ID NO: 3, each capable of detecting or capturing an exosome. The monoclonal antibody for detecting an exosome of the present invention is capable of detecting CD9, CD63 or CD81 on the exosome in a living body with an excellent sensitivity and specificity.

Abstract: An image fixing apparatus includes a heater including a substrate, a first electrode provided on one side of the substrate and a second electrode provided on the other side of the substrate; and a connector, connected with the heater, for receiving electric power, the connector including an electrically insulative housing, and a contact terminal provided inside the housing and having first spring contact contacted to the first electrode and a second spring contact contacted to the second electrode, wherein the first spring contact and the second spring contact are disposed at positions different as seen in a direction perpendicular to a surface of the substrate.

Abstract: A fixing device includes first and second members, a frame supporting the second member, and two pressure mechanisms provided on either end of the first member. The mechanism includes a lever having one end supported by the frame in a rotatable manner in a pressure direction, and a helical compression spring disposed between a first spring support provided on the other end of the lever and a second spring support on the frame. At least one of the first and second spring supports includes a first area and a second area closer to the spring in the axial direction than the first area, the first area is in contact with an area of the spring close to a winding end of the spring, and the second area is in contact with an area of the spring farther away from the winding end in a winding direction than the first area.

Abstract: An image fixing apparatus includes a heater for heating and fixing a toner image formed on a recording material; a thermosensitive element for sensing heat from the heater; and a tension spring for urging thermosensitive element toward the heater.

Abstract: A fixing device includes a cylindrical film, a back-up member in contact with an inner surface of the film, a roller configured to form a fixing nip portion with the back-up member via the film, and a metal bearing configured to rotatably hold a shaft of the roller. The fixing device further includes an insulating portion provided between an end surface of the film and the bearing, thereby suppressing occurrence of leakage between the bearing and the end surface of the film.

Abstract: An image fixing apparatus includes: a heater for heating and fixing a toner image formed on a recording material; a thermosensitive element for sensing heat from the heater; and a tension spring for urging the thermosensitive element toward the heater.

Abstract: An image fixing apparatus for heating and fixing an unfixed image formed on a recording material, comprising a heater including a substrate, a first electrode provided on one side of the substrate and a second electrode provided on the other side of the substrate; and a connector, connected with the heater, for receiving electric power, the connector including an electrically insulative housing, and a contact terminal provided inside the housing and having first spring contact contacted to the first electrode and a second spring contact contacted to the second electrode, wherein the contact terminal is swingable relative to the housing.

Abstract: A method for detecting a colorectal cancer, including the steps of measuring an amount of exosomes expressing CD147 in a body fluid sample derived from a test individual with an anti-CD147 monoclonal antibody or a fragment thereof; and comparing a signal intensity of exosomes in the step with a signal intensity in a control individual, wherein a case where the signal intensity in the test individual is found to be stronger than the signal intensity in the control individual serves as an index of the presence of the colorectal cancer. According to the method of the present invention, whether or not a sample provider has a high possibility of developing a colorectal cancer can be judged. Therefore, the method is useful because the sample provider can take a means of inhibiting the progression of cancer.

Abstract: A fixing apparatus includes a heater; a heater holding member for holding the heater; a temperature sensor, provided in contact with the heater through a hole provided in the heater holding member, for detecting a temperature of the heater; a holder for holding the sensor; and an urging member, provided between the sensor and the holder, for urging the sensor toward the heater, wherein the heater holding member includes a positioning portion for determining a position of the holder with respect to an urging direction of the urging member, and wherein the positioning portion is disposed at a position outside of a position of the sensor with respect to a direction perpendicular to a longitudinal direction of the heater.

Abstract: An image fixing apparatus includes a heater for heating and fixing a toner image formed on a recording material; a thermosensitive element for sensing heat from the heater; and a tension spring for urging thermosensitive element toward the heater.

Abstract: An image fixing apparatus includes a heater including a substrate, a first electrode provided on one side of the substrate and a second electrode provided on the other side of the substrate; and a connector, connected with the heater, for receiving electric power, the connector including an electrically insulative housing, and a contact terminal provided inside the housing and having first spring contact contacted to the first electrode and a second spring contact contacted to the second electrode, wherein the first spring contact and the second spring contact are disposed at positions different as seen in a direction perpendicular to a surface of the substrate.