Patents by Inventor Hideki Okunishi

Hideki Okunishi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preventive or therapeutic drugs for fibrosis containing chymase inhibitors as the active ingredient
    Patent number: 6500835
    Abstract: A medicament for the prevention or treatment containing a chymase inhibitor, as an effective component, which is a side effect-free, safe medicament for prevention or treatment of fibrosis of the skin or various viscera which suppresses the progression of the condition, prevents the progression of complications, and improves the quality of life of the patient, wherein a quinazoline derivative having the formula (I): or a pharmaceutically acceptable salt thereof is included therein.
    Type: Grant
    Filed: October 22, 2001
    Date of Patent: December 31, 2002
    Assignee: Suntory Limited
    Inventors: Harukazu Fukami, Hideki Okunishi, Eiichi Kakizoe
  • PREVENTIVE OR THERAPEUTIC DRUGS FOR FIBROSIS CONTAINING CHYMASE INHIBITORS AS THE ACTIVE INGREDIENT
    Publication number: 20020183338
    Abstract: A medicament for the prevention or treatment containing a chymase inhibitor, as an effective component, which is a side effect-free, safe medicament for prevention or treatment of fibrosis of the skin or various viscera which suppresses the progression of the condition, prevents the progression of complications, and improves the quality of life of the patient, wherein a quinazoline derivative having the formula (I): 1
    Type: Application
    Filed: October 22, 2001
    Publication date: December 5, 2002
    Inventors: Harukazu Fukami, Hideki Okunishi, Eiichi Kakizoe
  • Antirheumatic agent
    Patent number: 6149923
    Abstract: An antirheumatic agent comprising diethyl L-lysylcromoglycate of the following formula ##STR1## or a nontoxic salt thereof as an active ingredient. This compound has an anti-inflammatory action and immunomodulating action, is absorbed by oral administration to be delivered efficiently to local sites, and is associated with fewer side effects, so that it serves well as an antirheumatic agent that can be administered orally.
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: November 21, 2000
    Assignee: Kyoto Pharmaceutical Industries, Ltd.
    Inventors: Hiroaki Shirahase, Akihisa Yoshimi, Fumio Fukata, Hideki Okunishi, Yuta Kobayashi
  • Heterocyclic amide compounds and pharmaceutical use of the same
    Patent number: 5948785
    Abstract: Heterocyclic amide compounds of the formula (I) ##STR1## wherein each symbol is as defined in the specification, pharmacologically acceptable salts thereof, pharmaceutical compositions thereof and pharmaceutical use thereof. The heterocyclic amide compounds and pharmacologically acceptable salts thereof of the present invention have superior inhibitory activity against chymase groups in mammals inclusive of human, and can be administered orally or parenterally. Therefore, they are useful as chymase inhibitors and can be effective for the prophylaxis and treatment of various diseases caused by chymase, such as those caused by angiotensin II.
    Type: Grant
    Filed: October 27, 1997
    Date of Patent: September 7, 1999
    Assignee: The Green Cross Corporation
    Inventors: Fumihiko Akahoshi, Takuya Yoshimura, Masahiro Eda, Atsuyuki Ashimori, Hajime Fukuyama, Masahide Nakajima, Teruaki Imada, Hideki Okunishi, Mizuo Miyazaki