Abstract: Methods of judging the lymph node metastasis of stomach cancer, apparatuses for judging the lymph node metastasis of stomach cancer and kits used therefor are disclosed.

Abstract: The present invention provides a novel marker capable of accurately diagnosing the lymph node metastasis of stomach cancer. An mRNA, or a fragment thereof, coding for at least one protein selected from TFF1, AGR2, PRSS8, MUC1, MUC4 and MUC17 can be useful as a lymph node metastasis marker.

Abstract: The invention provides a method for judging whether cancer cells are present or not in a sample, comprising a obtaining step of obtaining values related to an expression level of a caner marker gene and a housekeeping gene; a first comparing step of comparing the value related to the expression level of the cancer marker gene with a first threshold value; a normalizing step of normalizing the value related to the expression level of the cancer marker gene based on the value related to the expression level of the housekeeping gene; a second comparing step of comparing the normalized value with a second threshold value; and a judging step of judging whether cancer cells are present or not in the sample based on comparison results obtained in the first and second comparing steps, as well as an apparatus for judging whether cancer cells are present or not.

Abstract: Disclosed is a primer for detecting mRNA for CK7. The primer comprises a first sequence on its 5?-terminal side and a second sequence on its 3?-terminal side. The first sequence has a length of 10 to 30 nucleotides, and can hybridize with a strand complementary to a first region which is a region contained in the sequence depicted in SEQ ID NO:1. The second sequence has a length of 10 to 30 nucleotides, and can hybridize with a second region which is located on the 3?-terminal side from the first region in the sequence depicted in SEQ ID NO:1.

Abstract: The invention provides a method for judging whether cancer cells are present or not in a sample, comprising a obtaining step of obtaining values related to an expression level of a caner marker gene and a housekeeping gene; a first comparing step of comparing the value related to the expression level of the cancer marker gene with a first threshold value; a normalizing step of normalizing the value related to the expression level of the cancer marker gene based on the value related to the expression level of the housekeeping gene; a second comparing step of comparing the normalized value with a second threshold value; and a judging step of judging whether cancer cells are present or not in the sample based on comparison results obtained in the first and second comparing steps, as well as an apparatus for judging whether cancer cells are present or not.

Abstract: Methods of judging the lymph node metastasis of stomach cancer, apparatuses for judging the lymph node metastasis of stomach cancer and kits used therefor are disclosed.

Abstract: The present invention provides a novel marker capable of accurately diagnosing the lymph node metastasis of stomach cancer. An mRNA, or a fragment thereof, coding for at least one protein selected from TFF1, AGR2, PRSS8, MUC1, MUC4 and MUC17 can be useful as a lymph node metastasis marker.

Abstract: A method of determining metastasis of a cancer to a lymph node, comprising the steps of: quantitating a polypeptide associated with cytokeratin, in a sample for detection prepared using a lymph node tissue collected from a living body, and determining metastasis of a cancer cell to the lymph node based on the quantitation result of the polypeptide is provided. Thereby, metastasis of a cancer to a lymph node can be determined with high reliance.

Abstract: A method for determining a cancer cell which has good precision and high reliability, including a step of quantitating an mRNA transcribed from a tumor marker gene contained in a biological sample, a step of quantitating a polypeptide translated from the tumor marker gene in the biological sample, and a step of detecting a cancer cell in the biological sample based on the quantitation result of the mRNA and the quantitation result of the polypeptide.

Abstract: A method and apparatus for judging the presence or absence of metastasis of malignant tumor is herein described. The method comprising: measuring an absolute amount of a tumor marker; and judging the presence or absence of metastasis of malignant tumor by comparing the absolute amount with a predetermined threshold value. The apparatus comprising: a measuring assembly for obtaining information related to an absolute amount of a tumor marker; and a computer for obtaining absolute amount of the tumor marker based on the information related to the absolute amount of the tumor marker, and judging the presence or absence of metastasis by comparing the absolute amount of the tumor marker with a predetermined threshold value.