Patents by Inventor Hideko Kosaka
Hideko Kosaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9873925Abstract: The present invention provides a method of recovering a heavy metal by which the variation in heavy metal recovery rate among samples can be suppressed. A mixture of a sample and a chelating agent capable of chelating with a heavy metal is prepared. A complex between a heavy metal being in the sample and the chelating agent is formed in the presence of a masking agent for a thiol group in the mixture. The heavy metal in the sample is recovered by recovering the complex. By this method, a heavy metal can be recovered with suppressing the variation in the recovery rate among samples. The chelating agent preferably is 1,5-diphenyl-3-thiocarbazone (dithizone). As the masking agent, N-ethylmaleimide, iodoacetamide, iodoacetic acid, or the like can be used.Type: GrantFiled: September 19, 2012Date of Patent: January 23, 2018Assignee: ARKRAY, Inc.Inventors: Yuka Shimomura, Hideko Kosaka
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Patent number: 9618519Abstract: A method for obtaining information about proteinuria and/or nephropathy from urine samples is provided for evaluating a urine sample that includes detecting proteins in the urine sample with two types of detection reagents that differ in reactivity to at least one urinary protein; and based on an indicator calculated using the results of the detection with the two types of detection reagents.Type: GrantFiled: August 4, 2015Date of Patent: April 11, 2017Assignee: ARKRAY, Inc.Inventors: Ryuichiro Nagamatsu, Shinya Nakajima, Hideko Kosaka
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Publication number: 20160041180Abstract: A method for obtaining information about proteinuria and/or nephropathy from urine samples is provided for evaluating a urine sample that includes detecting proteins in the urine sample with two types of detection reagents that differ in reactivity to at least one urinary protein; and based on an indicator calculated using the results of the detection with the two types of detection reagents.Type: ApplicationFiled: August 4, 2015Publication date: February 11, 2016Applicant: ARKRAY, INC.Inventors: Ryuichiro Nagamatsu, Shinya Nakajima, Hideko Kosaka
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Patent number: 8460877Abstract: The present invention relates to a technique of measuring a protein based on a degree of coloring in a liquid sample mixed with a protein measurement indicator. In the present invention, information reflecting creatinine concentration in the liquid sample is obtained, and then an influence quantity caused by creatinine to the protein concentration measurement is eliminated based on the information.Type: GrantFiled: January 21, 2005Date of Patent: June 11, 2013Assignee: Arkray, Inc.Inventors: Hideko Kosaka, Hisashi Sakamoto
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Publication number: 20110217207Abstract: A technique is provided, which makes it possible to easily judge whether or not an analysis tool to be used for an analysis process for a sample is authentic and which makes it possible to secure the reliability of an analysis result thereby. An identification apparatus for identifying an analysis tool having a reagent portion to be used for an analysis process for a sample is provided, wherein the analysis tool further includes an identifying marker portion which is formed by using an invisible substance, the identification apparatus comprising a light emitter which emits a light toward the identifying marker portion, a light receiver which receives a light emitted by the invisible substance for forming the identifying marker portion exposed with the emitted light emitted by the light emitter, and an identification unit which identifies the analysis tool on the basis of a light-receiving result obtained by the light receiver.Type: ApplicationFiled: March 2, 2011Publication date: September 8, 2011Applicant: ARKRAY, INC.Inventors: Koji Fujimoto, Noriaki Furusato, Hideko Kosaka
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Publication number: 20110020943Abstract: The present invention provides a dry testing tool with which a metal in the various types of samples such as biological samples, food, and the like can be measured very easily, rapidly, high sensitively, and specifically by a simple colorimetric method and a method for measuring the metal. The dry testing tool of the present invention is a dry testing tool for measuring a metal in a sample, including a porous support and a chelate dye, wherein the chelate dye is bound to the porous support by a hydrophobic bond. The measuring method of the present invention is a method for measuring a metal in a sample, including the steps of: forming a composite of the chelate dye and the metal in the sample by supplying the sample to the porous support to which a chelate dye is bound by a hydrophobic bond; and detecting the metal in the sample using a developed color of the composite.Type: ApplicationFiled: March 23, 2009Publication date: January 27, 2011Applicant: ARKRAY, INC.Inventors: Kazuhiro Okamoto, Isao Fukuta, Hisashi Sakamoto, Hideko Kosaka, Atsushi Nakao
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Patent number: 7820449Abstract: The present invention provides a novel test piece for creatinine measurement. The test piece includes a compound expressed by the following formula (1), a metal that forms a colored complex with the compound, and a buffer agent in a porous material. The amount of creatinine is determined by optically measuring a colored complex of the compound and the metal and evaluating the degree of inhibition of the colored complex formation by creatinine. In the formula (1), R1 represents H, SO3X, or COOX. R4 and R6 represent OH, SO3X, or COOX and may be either the same or different. R2, R3, R5, and R7 represent H, OH, Cl, Br, I, NO2, NO, or CH3 and may be either the same or different. Xs in the R1, R4, and R6 represent H, Na, K, or NH4 and may be either the same or different.Type: GrantFiled: October 15, 2003Date of Patent: October 26, 2010Assignee: ARKRAY, Inc.Inventor: Hideko Kosaka
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Publication number: 20080241850Abstract: The present invention relates to a technique of measuring a protein based on a degree of coloring in a liquid sample mixed with a protein measurement indicator. In the present invention, information reflecting creatinine concentration in the liquid sample is obtained, and then an influence quantity caused by creatinine to the protein concentration measurement is eliminated based on the information.Type: ApplicationFiled: January 21, 2005Publication date: October 2, 2008Applicant: ARKRAY, Inc.Inventors: Hideko Kosaka, Hisashi Sakamoto
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Publication number: 20060057730Abstract: The present invention relates to a technique for assaying a protein. With the present invention, a compound having a chemical structure expressed by the following Chemical Formula (1) is used as a protein assay indicator. In Chemical Formula (1), X1 is a halogen, a nitro group, or a nitroso group; X2 is a halogen; X3 is a halogen or hydrogen; X4 is a hydroxyl group or a salt thereof, and X5 is a carboxyl group or a salt thereof.Type: ApplicationFiled: August 4, 2003Publication date: March 16, 2006Applicant: ARKRAY, INC.Inventor: Hideko Kosaka
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Publication number: 20060057735Abstract: The present invention relates to a test piece for protein assay that is used for quantifying or semi-quantifying a protein and that contains an acidic pH indicator. This test piece for protein assay contains a surfactant as a sensitizer for increasing coloration sensitivity with respect to protein. A triphenylmethane-based indicator is used as the acidic pH indicator, for example. The present invention also provides a method for manufacturing a test piece for protein assay. With this method, a test piece for protein assay is manufactured by impregnating an absorbent carrier with an impregnant containing an acidic pH indicator and a sensitizer, and then drying this product. A surfactant is used as the sensitizer.Type: ApplicationFiled: August 4, 2003Publication date: March 16, 2006Applicant: ARKRAY, INC.Inventor: Hideko Kosaka
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Publication number: 20050266574Abstract: The present invention provides a novel test piece for creatinine measurement. The test piece includes a compound expressed by the following formula (1), a metal that forms a colored complex with the compound, and a buffer agent in a porous material. The amount of creatinine is determined by optically measuring a colored complex of the compound and the metal and evaluating the degree of inhibition of the colored complex formation by creatinine. In the formula (1), R1 represents H, SO3X, or COOX. R4 and R6 represent OH, SO3X, or COOX and may be either the same or different. R2, R3, R5, and R7 represent H, OH, Cl, Br, I, NO2, NO, or CH3 and may be either the same or different. Xs in the R1, R4, and R6 represent H, Na, K, or NH4 and may be either the same or different.Type: ApplicationFiled: October 15, 2003Publication date: December 1, 2005Applicant: Arkray, Inc.Inventor: Hideko Kosaka
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Patent number: 6797520Abstract: A composition capable of showing a color change sufficient for indicating the presence and/or concentration of a protein in a protein-containing liquid sample by contacting with the sample, comprising: indium or an indium compound, and a dye or pigment capable of forming a complex with indium.Type: GrantFiled: October 2, 2001Date of Patent: September 28, 2004Assignee: Kyoto Daiichi Kagaku Co., Ltd.Inventor: Hideko Kosaka
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Publication number: 20020037591Abstract: A composition capable of showing a color change sufficient for indicating the presence and/or concentration of a protein in a protein-containing liquid sample by contacting with the sample, comprising: indium or an indium compound, and a dye or pigment capable of forming a complex with indium.Type: ApplicationFiled: October 2, 2001Publication date: March 28, 2002Applicant: KYOTO DAIICHI KAGAKU CO., LTD.Inventor: Hideko Kosaka
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Patent number: 6319721Abstract: A method capable of showing a color change sufficient for indicating the presence and/or concentration of a protein in a protein-containing liquid sample by contacting with the sample, comprising: indium or an induim compound, and a dye or pigment capable of forming a complex with indium.Type: GrantFiled: December 23, 1999Date of Patent: November 20, 2001Assignee: Kyoto Daiichi Kagaku Co., Ltd.Inventor: Hideko Kosaka
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Patent number: 5955027Abstract: A reagent composition for detecting an analyte in a liquid sample, comprising an iron (III) complex of a tetrakis (N-hydroxyalkyl) ethylenediamine represented by the general formula (1): ##STR1## wherein n, m, p, and q are each independently integers of 1 to 3.Type: GrantFiled: May 23, 1997Date of Patent: September 21, 1999Assignee: Kyoto Daiichi Kagaku Co., Ltd.Inventor: Hideko Kosaka