Patents by Inventor Hideko Murooka

Hideko Murooka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6187926
    Abstract: The present invention relates to a process for producing a 4-quinolone derivative, comprising allowing an o-aminoacetophenone derivative to react with a formic acid in an aprotic solvent in the presence of a suitable base, and adding a protic solvent to the reaction mixture. This is a simple process for producing 4-quinolone derivatives, applicable to large-scale commercial production.
    Type: Grant
    Filed: October 18, 1999
    Date of Patent: February 13, 2001
    Assignee: Kirin Beer Kabushiki Kaisha
    Inventors: Tatsushi Osawa, Kazuo Kubo, Hideko Murooka, Tatsuo Nakajima
  • Patent number: 6143764
    Abstract: The present invention relates to novel quinoline derivatives and quinazoline derivatives represented by the following formula (I): ##STR1## [wherein R.sub.1 and R.sub.2 are each independently H or C.sub.1 -C.sub.4 -alkyl, or R.sub.1 and R.sub.2 together form C.sub.1 -C.sub.3 -alkylene, X is O, S or CH.sub.2, W is CH or N, and Q is a substituted aryl group or substituted heteroaryl group] and their pharmaceutically acceptable salts, having platelet-derived growth factor receptor autophosphorylation inhibitory activity, to pharmaceutical compositions containing these compounds, and to methods for the treatment of diseases associated with abnormal cell growth such as tumors.
    Type: Grant
    Filed: May 6, 1998
    Date of Patent: November 7, 2000
    Assignee: Kirin Beer Kabushiki Kaisha
    Inventors: Kazuo Kubo, Shinichi Ohyama, Toshiyuki Shimizu, Tsuyoshi Nishitoba, Shinichiro Kato, Hideko Murooka, Yoshiko Kobayashi