Patents by Inventor Hidenori Akatsuka

Hidenori Akatsuka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7531537
    Abstract: The present invention provides a benzofuran derivative of the formula [1]: wherein x is a group of the formula: —N? or —CH?; Y is an optionally substituted amino group, an optionally substituted cycloalkyl group or an optionally substituted saturated heterocyclic group; A is a single bond, a carbon chain optionally having a double bond within or at the end(s) of the chain, or an oxygen atom; R1 is a hydrogen atom or a halogen atom; Ring B is an optionally substituted benzene ring; and R3 is a hydrogen atom, or a pharmaceutically acceptable salt thereof, which is useful as a medicament, especially as an activated blood coagulation factor X inhibitor.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: May 12, 2009
    Assignee: Mitsubishi Tanabe Pharma Corporation
    Inventors: Takayuki Kawaguchi, Hidenori Akatsuka, Toru Iijima, Yasunori Tsuboi, Takashi Mitsui, Jun Murakami
  • Patent number: 7523732
    Abstract: An intake control system includes a control device that changes a length of an intake conduit between the length of connection and the length of disconnection that is shorter than the length of connection. The control device also includes a processor that determines whether or not the length of the intake conduit is to be changed. A condition for determining a change from the length of connection to the length of disconnection includes that an engine load is higher than a first threshold value. Also, a condition for determining a change from the length of disconnection to the length of connection includes that the engine load is lower than a second threshold value, which is lower than the first threshold value.
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: April 28, 2009
    Assignee: Yamaha Hatsudoki Kabushiki Kaisha
    Inventors: Daichi Noborio, Hidenori Akatsuka
  • Patent number: 7514449
    Abstract: The present invention provides a condensed furan compound of the formula (I): wherein Ring X is benzene, pyridine, or the like; Y is an optionally substituted amino, an optionally substituted cycloalkyl, an optionally substituted aryl, an optionally substituted saturated heterocyclic group, an optionally substituted unsaturated heterocyclic group; A is a single bond, lower alkylene, lower alkenylidene, lower alkenylene or an oxygen atom; R3 is hydrogen or the like; and, R4 is hydrogen, or the like, or pharmaceutically acceptable salts thereof, which is useful as a medicament, particularly, as an activated blood coagulation factor X inhibitor.
    Type: Grant
    Filed: January 8, 2004
    Date of Patent: April 7, 2009
    Assignee: Mitsubishi Tanabe Pharma Corporation
    Inventors: Takayuki Kawaguchi, Hidenori Akatsuka, Toru Iijima, Tatsuya Watanabe, Jun Murakami, Takashi Mitsui
  • Publication number: 20090023716
    Abstract: The present invention relates to a compound, useful as a mineralocorticoid receptor-modulating agent, of the following formula [I]: wherein Ring A is a benzene ring optionally having a substituent(s) other than R1 etc, R1 is a group of the formula: RaSO2NH— etc, Ra is an alkyl group etc, R2 and R3 are each a hydrogen atom, a phenyl group, an optionally substituted alkyl group etc, X is an oxygen atom etc, Y is a group of the formula: —C(?O)— etc, Ar is an optionally substituted aryl group or an optionally substituted heteroaryl group, Q is a single bond, an alkylene group etc, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: February 1, 2007
    Publication date: January 22, 2009
    Inventors: Toru Iijima, Yasuo Yamamoto, Hidenori Akatsuka, Takayuki Kawaguchi
  • Patent number: 7403847
    Abstract: An engine control device capable of decreasing engine output while giving less uncomfortable feeling to the rider in the event of a failure, with a simple configuration. Engine output is decreased when a failure has been detected in a throttle valve. When engine speed after the occurrence of the failure is larger than preset target rotational speed at the time of the occurrence of the failure, an ignition of the engine is cut off. The engine speed thereby can be decreased according to the preset target rotational speed. Thus, engine output can be decreased uniquely.
    Type: Grant
    Filed: April 20, 2006
    Date of Patent: July 22, 2008
    Assignee: Yamaha Hatsudoki Kabushiki Kaisha
    Inventors: Takeshi Matsuda, Hidenori Akatsuka, Daichi Noborio
  • Patent number: 7375119
    Abstract: The present invention provides an amide-type carboxamide derivative of the formula [1]: wherein X is a group of the formula: —N? or the formula: —CH?; R1 is a halogen atom, a lower alkyl group, and the like; R2 is a group of the formula: and the like; Y1 and Y2 are the same or different and each is a group selected from a halogen atom, a lower alkyl group, a lower alkoxy group, and the like; Ring A is phenyl group, and the like, or a pharmaceutically acceptable salt thereof, which is useful as an inhibitor of FXa.
    Type: Grant
    Filed: September 24, 2004
    Date of Patent: May 20, 2008
    Assignee: Mitsubishi Tanabe Pharma Corporation
    Inventors: Takayuki Kawaguchi, Hidenori Akatsuka, Masamichi Morimoto, Tatsuya Watanabe, Toru Iijima, Jun Murakami
  • Publication number: 20080092842
    Abstract: An intake control system includes a control device that changes a length of an intake conduit between the length of connection and the length of disconnection that is shorter than the length of connection. The control device also includes a processor that determines whether or not the length of the intake conduit is to be changed. A condition for determining a change from the length of connection to the length of disconnection includes that an engine load is higher than a first threshold value. Also, a condition for determining a change from the length of disconnection to the length of connection includes that the engine load is lower than a second threshold value, which is lower than the first threshold value.
    Type: Application
    Filed: September 18, 2007
    Publication date: April 24, 2008
    Applicant: YAMAHA HATSUDOKI KABUSHIKI KAISHA
    Inventors: Daichi Noborio, Hidenori Akatsuka
  • Publication number: 20080017166
    Abstract: An intake control device for an air intake system includes one or more stationary intake pipes that communicate with one or more intake ports of an engine. One or more movable intake pipes are movable relative to the stationary intake pipes and, in one position, cooperate with the stationary intake pipes to define engine air intake passages. An actuator applies a force tending to move the movable intake pipes in a first direction. A controller controls the actuator. The movable intake pipes are inhibited from moving beyond a first position in the first direction. The controller directs the actuator to apply a force to the movable intake pipes when the movable intake pipes are in the first position.
    Type: Application
    Filed: July 20, 2007
    Publication date: January 24, 2008
    Applicant: YAMAHA HATSUDOKI KABUSHIKI KAISHA
    Inventors: Daichi Noborio, Hidenori Akatsuka
  • Patent number: 7295913
    Abstract: An engine control apparatus for a motorcycle capable of detecting an abnormality such that there is no change in vehicle behavior even when the abnormality is brought about. A control CPU controls injection and ignition of an engine and a throttle valve. A monitor CPU detects an abnormality of the engine control apparatus. The control CPU calculates a fuel injection amount, an ignition timing, and an opening degree of the throttle valve necessary for controlling the engine and executes a predetermined engine control. The monitor CPU detects the abnormality of the engine control apparatus. A comparison of control values to detect the abnormality by the monitor CPU is executed by a detection interval equal to or smaller than 10 ms.
    Type: Grant
    Filed: August 29, 2006
    Date of Patent: November 13, 2007
    Assignee: Yamaha Hatsudoki Kabushiki Kaisha
    Inventors: Takeshi Matsuda, Hidenori Akatsuka, Daichi Noborio
  • Patent number: 7260471
    Abstract: An engine (drive force) control apparatus for a motorcycle that prevents a change in vehicle behavior by noise or the like. A control CPU electronically controls injection and ignition of fuel and a throttle valve. An abnormality detecting portion detects an abnormality of the engine control apparatus by a predetermined abnormality detecting period. When the abnormality is detected, primary abnormality processing of the engine control apparatus is executed. When the abnormality is not detected, primary abnormality processing is released and an electronic control at normal time of the engine control apparatus is executed. When an abnormality detecting signal detected by the abnormality detecting portion continues even an elapse of a predetermined abnormality determining time period, primary abnormality processing is shifted to secondary abnormality processing.
    Type: Grant
    Filed: August 29, 2006
    Date of Patent: August 21, 2007
    Assignee: Yamaha Hatsudoki Kabushiki Kaisha
    Inventors: Takeshi Matsuda, Hidenori Akatsuka, Daichi Noborio
  • Publication number: 20070050122
    Abstract: An engine control apparatus for a motorcycle capable of detecting an abnormality such that there is no change in vehicle behavior even when the abnormality is brought about. A control CPU controls injection and ignition of an engine and a throttle valve. A monitor CPU detects an abnormality of the engine control apparatus. The control CPU calculates a fuel injection amount, an ignition timing, and an opening degree of the throttle valve necessary for controlling the engine and executes a predetermined engine control. The monitor CPU detects the abnormality of the engine control apparatus. A comparison of control values to detect the abnormality by the monitor CPU is executed by a detection interval equal to or smaller than 10 ms.
    Type: Application
    Filed: August 29, 2006
    Publication date: March 1, 2007
    Applicant: YAMAHA HATSUDOKI KABUSHIKI KAISHA
    Inventors: Takeshi Matsuda, Hidenori Akatsuka, Daichi Noborio
  • Publication number: 20070050125
    Abstract: An engine (drive force) control apparatus for a motorcycle that prevents a change in vehicle behavior by noise or the like. A control CPU electronically controls injection and ignition of fuel and a throttle valve. An abnormality detecting portion detects an abnormality of the engine control apparatus by a predetermined abnormality detecting period. When the abnormality is detected, primary abnormality processing of the engine control apparatus is executed. When the abnormality is not detected, primary abnormality processing is released and an electronic control at normal time of the engine control apparatus is executed. When an abnormality detecting signal detected by the abnormality detecting portion continues even an elapse of a predetermined abnormality determining time period, primary abnormality processing is shifted to secondary abnormality processing.
    Type: Application
    Filed: August 29, 2006
    Publication date: March 1, 2007
    Applicant: YAMAHA HATSUDOKI KABUSHIKI KAISHA
    Inventors: Takeshi Matsuda, Hidenori Akatsuka, Daichi Noborio
  • Publication number: 20060287329
    Abstract: The present invention provides an amide-type carboxamide derivative of the formula [1]: wherein X is a group of the formula: —N? or the formula: —CH?; R1 is a halogen atom, a lower alkyl group, and the like; R2 is a group of the formula: and the like; Y1 and Y2 are the same or different and each is a group selected from a halogen atom, a lower alkyl group, a lower alkoxy group, and the like; Ring A is phenyl group, and the like, or a pharmaceutically acceptable salt thereof, which is useful as an inhibitor of FXa.
    Type: Application
    Filed: September 24, 2004
    Publication date: December 21, 2006
    Inventors: Takayuki Kawaguchi, Hidenori Akatsuka, Masamichi Morimoto, Tatsuya Watanabe, Toru Iijima, Jun Murakami
  • Publication number: 20060287796
    Abstract: An engine control device capable of decreasing engine output while giving less uncomfortable feeling to the rider in the event of a failure, with a simple configuration. Engine output is decreased when a failure has been detected in a throttle valve. When engine speed after the occurrence of the failure is larger than preset target rotational speed at the time of the occurrence of the failure, an ignition of the engine is cut off. The engine speed thereby can be decreased according to the preset target rotational speed. Thus, engine output can be decreased uniquely.
    Type: Application
    Filed: April 20, 2006
    Publication date: December 21, 2006
    Inventors: Takeshi Matsuda, Hidenori Akatsuka, Daichi Noborio
  • Publication number: 20060247273
    Abstract: The present invention provides a carbamoyl-type benzofuran derivative of the formula [1]: wherein Ring Z is a group of the formula: etc.; A is a single bond, and the like; Y is a cycloalkanediyl group, etc.; R4 and R5 are the same or different and each is an optionally substituted lower alkyl group, etc.; R1 is a halogen atom, etc.; Ring B of the formula: is an optionally substituted benzene ring; and R3 is a hydrogen atom. etc., or a pharmaceutically acceptable salt thereof, which is useful as an FXa inhibitor.
    Type: Application
    Filed: September 24, 2004
    Publication date: November 2, 2006
    Inventors: Takayuki Kawaguchi, Hidenori Akatsuka, Masamichi Morimoto, Toru Iijima, Jun Murakami
  • Publication number: 20060094724
    Abstract: The present invention provides a condensed furan compound of the formula (I): wherein Ring X is benzene, pyridine, or the like; Y is an optionally substituted amino, an optionally substituted cycloalkyl, an optionally substituted aryl, an optionally substituted saturated heterocyclic group, an optionally substituted unsaturated heterocyclic group; A is a single bond, lower alkylene, lower alkenylidene, lower alkenylene or an oxygen atom; R3 is hydrogen or the like; and, R4 is hydrogen, or the like, or pharmaceutically acceptable salts thereof, which is useful as a medicament, particularly, as an activated blood coagulation factor X inhibitor.
    Type: Application
    Filed: January 8, 2004
    Publication date: May 4, 2006
    Inventors: Takayuki Kawaguchi, Hidenori Akatsuka, Toru Iijima, Tatsuya Watanabe, Jun Murakami, Takashi Mitsui
  • Publication number: 20050282808
    Abstract: The present invention provides a benzofuran derivative of the formula [1]: wherein x is a group of the formula: —N? or —CH?; Y is an optionally substituted amino group, an optionally substituted cycloalkyl group or an optionally substituted saturated heterocyclic group; A is a single bond, a carbon chain optionally having a double bond within or at the end(s) of the chain, or an oxygen atom; R1 is a hydrogen atom or a halogen atom; Ring B is an optionally substituted benzene ring; and R3 is a hydrogen atom, or a pharmaceutically acceptable salt thereof, which is useful as a medicament, especially as an activated blood coagulation factor X inhibitor.
    Type: Application
    Filed: March 27, 2003
    Publication date: December 22, 2005
    Inventors: Takayuki Kawaguchi, Hidenori Akatsuka, Toru Iijima, Yasunori Tsuboi, Takashi Mitsui, Jun Murakami
  • Patent number: 5626120
    Abstract: A control system and method for an internal combustion engine that employs a throttle position sensor and an engine speed sensor. The initial fuel air ratio control is based upon a map experimentally determined from throttle position and engine speed settings for optimum performance. However, in the event the throttle position sensor is deemed to be inaccurate, then another method is utilized for engine control purposes. In most embodiments, a map is also used in the other way.
    Type: Grant
    Filed: June 5, 1996
    Date of Patent: May 6, 1997
    Assignee: Yamaha Hatsudoki Kabushiki Kaisha
    Inventor: Hidenori Akatsuka