Patents by Inventor Hidenori Akatsuka
Hidenori Akatsuka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7531537Abstract: The present invention provides a benzofuran derivative of the formula [1]: wherein x is a group of the formula: —N? or —CH?; Y is an optionally substituted amino group, an optionally substituted cycloalkyl group or an optionally substituted saturated heterocyclic group; A is a single bond, a carbon chain optionally having a double bond within or at the end(s) of the chain, or an oxygen atom; R1 is a hydrogen atom or a halogen atom; Ring B is an optionally substituted benzene ring; and R3 is a hydrogen atom, or a pharmaceutically acceptable salt thereof, which is useful as a medicament, especially as an activated blood coagulation factor X inhibitor.Type: GrantFiled: March 27, 2003Date of Patent: May 12, 2009Assignee: Mitsubishi Tanabe Pharma CorporationInventors: Takayuki Kawaguchi, Hidenori Akatsuka, Toru Iijima, Yasunori Tsuboi, Takashi Mitsui, Jun Murakami
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Patent number: 7523732Abstract: An intake control system includes a control device that changes a length of an intake conduit between the length of connection and the length of disconnection that is shorter than the length of connection. The control device also includes a processor that determines whether or not the length of the intake conduit is to be changed. A condition for determining a change from the length of connection to the length of disconnection includes that an engine load is higher than a first threshold value. Also, a condition for determining a change from the length of disconnection to the length of connection includes that the engine load is lower than a second threshold value, which is lower than the first threshold value.Type: GrantFiled: September 18, 2007Date of Patent: April 28, 2009Assignee: Yamaha Hatsudoki Kabushiki KaishaInventors: Daichi Noborio, Hidenori Akatsuka
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Patent number: 7514449Abstract: The present invention provides a condensed furan compound of the formula (I): wherein Ring X is benzene, pyridine, or the like; Y is an optionally substituted amino, an optionally substituted cycloalkyl, an optionally substituted aryl, an optionally substituted saturated heterocyclic group, an optionally substituted unsaturated heterocyclic group; A is a single bond, lower alkylene, lower alkenylidene, lower alkenylene or an oxygen atom; R3 is hydrogen or the like; and, R4 is hydrogen, or the like, or pharmaceutically acceptable salts thereof, which is useful as a medicament, particularly, as an activated blood coagulation factor X inhibitor.Type: GrantFiled: January 8, 2004Date of Patent: April 7, 2009Assignee: Mitsubishi Tanabe Pharma CorporationInventors: Takayuki Kawaguchi, Hidenori Akatsuka, Toru Iijima, Tatsuya Watanabe, Jun Murakami, Takashi Mitsui
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Publication number: 20090023716Abstract: The present invention relates to a compound, useful as a mineralocorticoid receptor-modulating agent, of the following formula [I]: wherein Ring A is a benzene ring optionally having a substituent(s) other than R1 etc, R1 is a group of the formula: RaSO2NH— etc, Ra is an alkyl group etc, R2 and R3 are each a hydrogen atom, a phenyl group, an optionally substituted alkyl group etc, X is an oxygen atom etc, Y is a group of the formula: —C(?O)— etc, Ar is an optionally substituted aryl group or an optionally substituted heteroaryl group, Q is a single bond, an alkylene group etc, or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: February 1, 2007Publication date: January 22, 2009Inventors: Toru Iijima, Yasuo Yamamoto, Hidenori Akatsuka, Takayuki Kawaguchi
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Patent number: 7403847Abstract: An engine control device capable of decreasing engine output while giving less uncomfortable feeling to the rider in the event of a failure, with a simple configuration. Engine output is decreased when a failure has been detected in a throttle valve. When engine speed after the occurrence of the failure is larger than preset target rotational speed at the time of the occurrence of the failure, an ignition of the engine is cut off. The engine speed thereby can be decreased according to the preset target rotational speed. Thus, engine output can be decreased uniquely.Type: GrantFiled: April 20, 2006Date of Patent: July 22, 2008Assignee: Yamaha Hatsudoki Kabushiki KaishaInventors: Takeshi Matsuda, Hidenori Akatsuka, Daichi Noborio
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Patent number: 7375119Abstract: The present invention provides an amide-type carboxamide derivative of the formula [1]: wherein X is a group of the formula: —N? or the formula: —CH?; R1 is a halogen atom, a lower alkyl group, and the like; R2 is a group of the formula: and the like; Y1 and Y2 are the same or different and each is a group selected from a halogen atom, a lower alkyl group, a lower alkoxy group, and the like; Ring A is phenyl group, and the like, or a pharmaceutically acceptable salt thereof, which is useful as an inhibitor of FXa.Type: GrantFiled: September 24, 2004Date of Patent: May 20, 2008Assignee: Mitsubishi Tanabe Pharma CorporationInventors: Takayuki Kawaguchi, Hidenori Akatsuka, Masamichi Morimoto, Tatsuya Watanabe, Toru Iijima, Jun Murakami
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Publication number: 20080092842Abstract: An intake control system includes a control device that changes a length of an intake conduit between the length of connection and the length of disconnection that is shorter than the length of connection. The control device also includes a processor that determines whether or not the length of the intake conduit is to be changed. A condition for determining a change from the length of connection to the length of disconnection includes that an engine load is higher than a first threshold value. Also, a condition for determining a change from the length of disconnection to the length of connection includes that the engine load is lower than a second threshold value, which is lower than the first threshold value.Type: ApplicationFiled: September 18, 2007Publication date: April 24, 2008Applicant: YAMAHA HATSUDOKI KABUSHIKI KAISHAInventors: Daichi Noborio, Hidenori Akatsuka
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Publication number: 20080017166Abstract: An intake control device for an air intake system includes one or more stationary intake pipes that communicate with one or more intake ports of an engine. One or more movable intake pipes are movable relative to the stationary intake pipes and, in one position, cooperate with the stationary intake pipes to define engine air intake passages. An actuator applies a force tending to move the movable intake pipes in a first direction. A controller controls the actuator. The movable intake pipes are inhibited from moving beyond a first position in the first direction. The controller directs the actuator to apply a force to the movable intake pipes when the movable intake pipes are in the first position.Type: ApplicationFiled: July 20, 2007Publication date: January 24, 2008Applicant: YAMAHA HATSUDOKI KABUSHIKI KAISHAInventors: Daichi Noborio, Hidenori Akatsuka
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Patent number: 7295913Abstract: An engine control apparatus for a motorcycle capable of detecting an abnormality such that there is no change in vehicle behavior even when the abnormality is brought about. A control CPU controls injection and ignition of an engine and a throttle valve. A monitor CPU detects an abnormality of the engine control apparatus. The control CPU calculates a fuel injection amount, an ignition timing, and an opening degree of the throttle valve necessary for controlling the engine and executes a predetermined engine control. The monitor CPU detects the abnormality of the engine control apparatus. A comparison of control values to detect the abnormality by the monitor CPU is executed by a detection interval equal to or smaller than 10 ms.Type: GrantFiled: August 29, 2006Date of Patent: November 13, 2007Assignee: Yamaha Hatsudoki Kabushiki KaishaInventors: Takeshi Matsuda, Hidenori Akatsuka, Daichi Noborio
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Patent number: 7260471Abstract: An engine (drive force) control apparatus for a motorcycle that prevents a change in vehicle behavior by noise or the like. A control CPU electronically controls injection and ignition of fuel and a throttle valve. An abnormality detecting portion detects an abnormality of the engine control apparatus by a predetermined abnormality detecting period. When the abnormality is detected, primary abnormality processing of the engine control apparatus is executed. When the abnormality is not detected, primary abnormality processing is released and an electronic control at normal time of the engine control apparatus is executed. When an abnormality detecting signal detected by the abnormality detecting portion continues even an elapse of a predetermined abnormality determining time period, primary abnormality processing is shifted to secondary abnormality processing.Type: GrantFiled: August 29, 2006Date of Patent: August 21, 2007Assignee: Yamaha Hatsudoki Kabushiki KaishaInventors: Takeshi Matsuda, Hidenori Akatsuka, Daichi Noborio
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Publication number: 20070050122Abstract: An engine control apparatus for a motorcycle capable of detecting an abnormality such that there is no change in vehicle behavior even when the abnormality is brought about. A control CPU controls injection and ignition of an engine and a throttle valve. A monitor CPU detects an abnormality of the engine control apparatus. The control CPU calculates a fuel injection amount, an ignition timing, and an opening degree of the throttle valve necessary for controlling the engine and executes a predetermined engine control. The monitor CPU detects the abnormality of the engine control apparatus. A comparison of control values to detect the abnormality by the monitor CPU is executed by a detection interval equal to or smaller than 10 ms.Type: ApplicationFiled: August 29, 2006Publication date: March 1, 2007Applicant: YAMAHA HATSUDOKI KABUSHIKI KAISHAInventors: Takeshi Matsuda, Hidenori Akatsuka, Daichi Noborio
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Publication number: 20070050125Abstract: An engine (drive force) control apparatus for a motorcycle that prevents a change in vehicle behavior by noise or the like. A control CPU electronically controls injection and ignition of fuel and a throttle valve. An abnormality detecting portion detects an abnormality of the engine control apparatus by a predetermined abnormality detecting period. When the abnormality is detected, primary abnormality processing of the engine control apparatus is executed. When the abnormality is not detected, primary abnormality processing is released and an electronic control at normal time of the engine control apparatus is executed. When an abnormality detecting signal detected by the abnormality detecting portion continues even an elapse of a predetermined abnormality determining time period, primary abnormality processing is shifted to secondary abnormality processing.Type: ApplicationFiled: August 29, 2006Publication date: March 1, 2007Applicant: YAMAHA HATSUDOKI KABUSHIKI KAISHAInventors: Takeshi Matsuda, Hidenori Akatsuka, Daichi Noborio
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Publication number: 20060287329Abstract: The present invention provides an amide-type carboxamide derivative of the formula [1]: wherein X is a group of the formula: —N? or the formula: —CH?; R1 is a halogen atom, a lower alkyl group, and the like; R2 is a group of the formula: and the like; Y1 and Y2 are the same or different and each is a group selected from a halogen atom, a lower alkyl group, a lower alkoxy group, and the like; Ring A is phenyl group, and the like, or a pharmaceutically acceptable salt thereof, which is useful as an inhibitor of FXa.Type: ApplicationFiled: September 24, 2004Publication date: December 21, 2006Inventors: Takayuki Kawaguchi, Hidenori Akatsuka, Masamichi Morimoto, Tatsuya Watanabe, Toru Iijima, Jun Murakami
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Publication number: 20060287796Abstract: An engine control device capable of decreasing engine output while giving less uncomfortable feeling to the rider in the event of a failure, with a simple configuration. Engine output is decreased when a failure has been detected in a throttle valve. When engine speed after the occurrence of the failure is larger than preset target rotational speed at the time of the occurrence of the failure, an ignition of the engine is cut off. The engine speed thereby can be decreased according to the preset target rotational speed. Thus, engine output can be decreased uniquely.Type: ApplicationFiled: April 20, 2006Publication date: December 21, 2006Inventors: Takeshi Matsuda, Hidenori Akatsuka, Daichi Noborio
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Publication number: 20060247273Abstract: The present invention provides a carbamoyl-type benzofuran derivative of the formula [1]: wherein Ring Z is a group of the formula: etc.; A is a single bond, and the like; Y is a cycloalkanediyl group, etc.; R4 and R5 are the same or different and each is an optionally substituted lower alkyl group, etc.; R1 is a halogen atom, etc.; Ring B of the formula: is an optionally substituted benzene ring; and R3 is a hydrogen atom. etc., or a pharmaceutically acceptable salt thereof, which is useful as an FXa inhibitor.Type: ApplicationFiled: September 24, 2004Publication date: November 2, 2006Inventors: Takayuki Kawaguchi, Hidenori Akatsuka, Masamichi Morimoto, Toru Iijima, Jun Murakami
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Publication number: 20060094724Abstract: The present invention provides a condensed furan compound of the formula (I): wherein Ring X is benzene, pyridine, or the like; Y is an optionally substituted amino, an optionally substituted cycloalkyl, an optionally substituted aryl, an optionally substituted saturated heterocyclic group, an optionally substituted unsaturated heterocyclic group; A is a single bond, lower alkylene, lower alkenylidene, lower alkenylene or an oxygen atom; R3 is hydrogen or the like; and, R4 is hydrogen, or the like, or pharmaceutically acceptable salts thereof, which is useful as a medicament, particularly, as an activated blood coagulation factor X inhibitor.Type: ApplicationFiled: January 8, 2004Publication date: May 4, 2006Inventors: Takayuki Kawaguchi, Hidenori Akatsuka, Toru Iijima, Tatsuya Watanabe, Jun Murakami, Takashi Mitsui
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Publication number: 20050282808Abstract: The present invention provides a benzofuran derivative of the formula [1]: wherein x is a group of the formula: —N? or —CH?; Y is an optionally substituted amino group, an optionally substituted cycloalkyl group or an optionally substituted saturated heterocyclic group; A is a single bond, a carbon chain optionally having a double bond within or at the end(s) of the chain, or an oxygen atom; R1 is a hydrogen atom or a halogen atom; Ring B is an optionally substituted benzene ring; and R3 is a hydrogen atom, or a pharmaceutically acceptable salt thereof, which is useful as a medicament, especially as an activated blood coagulation factor X inhibitor.Type: ApplicationFiled: March 27, 2003Publication date: December 22, 2005Inventors: Takayuki Kawaguchi, Hidenori Akatsuka, Toru Iijima, Yasunori Tsuboi, Takashi Mitsui, Jun Murakami
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Patent number: 5626120Abstract: A control system and method for an internal combustion engine that employs a throttle position sensor and an engine speed sensor. The initial fuel air ratio control is based upon a map experimentally determined from throttle position and engine speed settings for optimum performance. However, in the event the throttle position sensor is deemed to be inaccurate, then another method is utilized for engine control purposes. In most embodiments, a map is also used in the other way.Type: GrantFiled: June 5, 1996Date of Patent: May 6, 1997Assignee: Yamaha Hatsudoki Kabushiki KaishaInventor: Hidenori Akatsuka