Patents by Inventor Hidenori Hirose

Hidenori Hirose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11773374
    Abstract: Provided is a method for producing platelets, in which damage to platelets is suppressed compared with a method in which platelets are separated using a filter from a megakaryocyte culture, and then the platelets are concentrated using a hollow fiber membrane and are further washed using the hollow fiber membrane, and purified platelets can be produced in a shorter period of time compared with the time that is taken to perform the above-described method so as to reduce damage to platelets. The method for producing purified platelets of the present invention includes a concentrating step of concentrating a megakaryocyte culture, and a centrifuging step of centrifuging platelets from an obtained concentrate.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: October 3, 2023
    Assignee: MEGAKARYON CORPORATION
    Inventors: Hiroya Takahara, Junko Tomizuka, Haruki Okamoto, Hidenori Hirose
  • Patent number: 10851343
    Abstract: The present invention provides a method for producing purified platelets from a culture of megakaryocytes, comprising a first centrifugal separation step of centrifugally separating the culture at a centrifugal force of 150×g to 550×g, and a second centrifugal separation step of centrifugally separating, at a centrifugal force of 600×g to 4000×g, a liquid component recovered in the first centrifugal separation step.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: December 1, 2020
    Assignee: Megakaryon Corporation
    Inventors: Hidenori Hirose, Michiko Ueda
  • Publication number: 20180282697
    Abstract: The present invention provides a method for producing purified platelets from a culture of megakaryocytes, comprising a first centrifugal separation step of centrifugally separating the culture at a centrifugal force of 150×g to 550×g, and a second centrifugal separation step of centrifugally separating, at a centrifugal force of 600×g to 4000×g, a liquid component recovered in the first centrifugal separation step.
    Type: Application
    Filed: October 14, 2016
    Publication date: October 4, 2018
    Inventors: Hidenori Hirose, Michiko Ueda