Abstract: A culture container transportation set suitable for cultured state-maintaining transportation is provided. A culture container transportation set A1 includes: a culture container 13 including a vessel 13 made up of a bottom wall 11 and a tubular side wall 12 rising from the bottom wall 11; a flexible cover 2 covering an upper edge portion 121 of the side wall 12; a hard pressing member 3 provided on the cover 2; a cushioning material 4 of shape restorability; and a housing container 6 that houses the culture container 1, the cover 2, the pressing member 3 and the cushioning material 4 in an assembled state in which these components are stacked while pressing these components from above and below. The cushioning material 4 is provided between the housing container 6 and the culture container 1 or between the pressing member 3 and the housing container 6.

Abstract: A culture container transporting set A1 includes: a culture container 1 having a vessel 13 made of a bottom wall 11 and a tubular side wall 12 raised from the bottom wall 11; a flexible cover 2 that covers an upper end 121 of the side wall 12; a presser member 3 that is relatively hard and placed on the cover 2; and a holder 5 that holds the culture container 1, the cover 2 and the presser member 3 integral as stacked into an assembled state, by applying pressure from top and bottom.

Abstract: A culture container transportation set suitable for cultured state-maintaining transportation is provided. A culture container transportation set A1 includes: a culture container 13 including a vessel 13 made up of a bottom wall 11 and a tubular side wall 12 rising from the bottom wall 11; a flexible cover 2 covering an upper edge portion 121 of the side wall 12; a hard pressing member 3 provided on the cover 2; a cushioning material 4 of shape restorability; and a housing container 6 that houses the culture container 1, the cover 2, the pressing member 3 and the cushioning material 4 in an assembled state in which these components are stacked while pressing these components from above and below. The cushioning material 4 is provided between the housing container 6 and the culture container 1 or between the pressing member 3 and the housing container 6.

Abstract: A culture container transporting set A1 includes: a culture container 1 having a vessel 13 made of a bottom wall 11 and a tubular side wall 12 raised from the bottom wall 11; a flexible cover 2 that covers an upper end 121 of the side wall 12; a presser member 3 that is relatively hard and placed on the cover 2; and a holder 5 that holds the culture container 1, the cover 2 and the presser member 3 integral as stacked into an assembled state, by applying pressure from top and bottom.

Abstract: To provide a culture flask A1, a vessel 1 is made up of a bottom wall 11, standing walls rising from the periphery of the bottom wall 11 such as front and rear walls 12, 13 spaced apart in a front-back direction and a pair of side walls 14 laterally spaced and connected to the front and rear walls 12, 13, and a ceiling wall 15 positioned above the bottom wall 11 to cover a region surrounded by the front wall 12, rear wall 13 and paired side walls 14 as viewed in a vertical direction. A cylindrical neck 2 with an open end is attached to the front wall 12. The ceiling wall 15 includes a low region positioned offset in the vertical direction toward the bottom wall 11 from an upper end P1 of the neck 2 attached to the front wall 12.

Abstract: The present invention provides a method of analyzing the specific interaction between a molecule to be analyzed and a molecule that specifically interacts with the former molecule on a solid phase using a molecule-immobilized solid phase support mixture prepared by binding the subject molecule to the solid phase support without specifying the binding position on the molecule side, particularly a method wherein the immobilization is conducted via a spacer introduced to the molecule without specifying the binding position on the molecule side, which method makes it possible to identify and select only a molecule that exhibits a specific interaction with a molecule to be analyzed, without an investigation of structure-activity correlation, which has conventionally been essential, and hence enables an analysis of the interaction between these molecules.

Abstract: A hinge board having a hinge bending part and a rigid part includes: not less than two flexible wiring boards including a polyimide sheet layer, a conductor layer having a circuit formed on both sides or one side of the polyimide sheet layer, and a coverlay film layer covering the conductor layer; and a bonding material for bonding the flexible wiring boards. At least one of the flexible wiring boards is a flexible double-sided wiring board including the conductor layers on both sides of the polyimide sheet layer. Moreover, the flexible wiring boards are bonded to each other in the rigid part by use of the bonding material in such a manner that a space part is formed between the flexible wiring boards in the hinge bending part.

Abstract: It is intended to provide a protein participating in the regulation of sugar production, a polynucleotide encoding the same, a method of screening a compound participating in the regulation of sugar production and a drug for treating or preventing diabetes which contains the compound participating in the regulation of sugar production. A polynucleotide encoding a protein specifically binding to a substance WF00144 is found out from rat liver cells and thus a protein participating in the regulation of sugar production and a polynucleotide encoding the same are provided. Moreover, a method and a substance relating to a method of treating and preventing diabetes are found out and thus a method of treating diabetes relating to the regulation of sugar production relating to the method of treating and preventing diabetes is provided.

Abstract: A hinge board having a hinge bending part and a rigid part includes: not less than two flexible wiring boards including a polyimide sheet layer, a conductor layer having a circuit formed on both sides or one side of the polyimide sheet layer, and a coverlay film layer covering the conductor layer; and a bonding material for bonding the flexible wiring boards. At least one of the flexible wiring boards is a flexible double-sided wiring board including the conductor layers on both sides of the polyimide sheet layer. Moreover, the flexible wiring boards are bonded to each other in the rigid part by use of the bonding material in such a manner that a space part is formed between the flexible wiring boards in the hinge bending part.

Abstract: The present invention relates to reduced FK228 of the formula (I) wherein R1 and R2 are the same or different and each is a hydrogen atom or a thiol-protecting group, or a salt thereof, and a histone deacetylase inhibitor containing this compound, an expression potentiator and a reactivation promoter of a transgene, and pharmaceutical agents containing them as active ingredients. The reduced FK228 or a salt thereof has a strong histone deacetylase inhibitory activity and this compound can be used for the prophylaxis or treatment of various diseases, in which histone deacetylation is involved, and for the gene therapy of such diseases.

Abstract: The present invention provides a method of analyzing the specific interaction between a molecule to be analyzed and a molecule that specifically interacts with the former molecule on a solid phase using a molecule-immobilized solid phase support mixture prepared by binding the subject molecule to the solid phase support without specifying the binding position on the molecule side, particularly a method wherein the immobilization is conducted via a spacer introduced to the molecule without specifying the binding position on the molecule side, which method makes it possible to identify and select only a molecule that exhibits a specific interaction with a molecule to be analyzed, without an investigation of structure-activity correlation, which has conventionally been essential, and hence enables an analysis of the interaction between these molecules.

Abstract: It is intended to provide a protein participating in the regulation of sugar production, a polynucleotide encoding the same, a method of screening a compound participating in the regulation of sugar production and a drug for treating or preventing diabetes which contains the compound participating in the regulation of sugar production. A polynucleotide encoding a protein specifically binding to a substance WF00144 is found out from rat liver cells and thus a protein participating in the regulation of sugar production and a polynucleotide encoding the same are provided. Moreover, a method and a substance relating to a method of treating and preventing diabetes are found out and thus a method of treating diabetes relating to the regulation of sugar production relating to the method of treating and preventing diabetes is provided.

Abstract: The present invention relates to reduced FK228 of the formula (I) 1

Abstract: WB2663 substance-producing bacteria belonging to the genus Pseudomonas are cultured to produce a physiologically active substance, from which are isolated neutral substances WB2663A, WB2663B and WB2663C having respective specific rotations[.alpha.].sub.D.sup.23 : -36.degree. (C=0.5, CH.sub.2 Cl.sub.2),[.alpha.].sub.D.sup.23 : -12.degree. (C=0.5, CH.sub.2 Cl.sub.2),[.alpha.].sub.D.sup.23 : -9.degree. (C=0.5, CH.sub.2 Cl.sub.2),These substances have an excellent antitumor effect.

Abstract: The invention relates to compounds of antitumor activity of the formula: ##STR1## ps in which R.sup.1 is hydrogen, lower allkyl, halo(lower)alkyl or aryl,R.sup.2 is hydrogen, hydroxy or protected hydroxy,R.sup.3 is hydrogen,R.sup.4 is aminocarboxy(lower)alkyl, protected amino(lower)alkyl or protected aminocarboxy(lower)alkyl, andR.sup.5 is hydrogen or lower alkyl, or its pharmaceutical acceptable salt.