Abstract: A nucleic acid structural analysis method includes: an HAD-MSn analysis step (101) of introducing a hydrogen radical into a space in which an ion derived from a test nucleic acid is present to perform dissociation of the ion, and performing mass spectrometry on a plurality of fragment ions generated by the dissociation to collect m/z information on the plurality of fragment ions; and a structure estimation step (103) of estimating a structure of the test nucleic acid on a basis of the m/z information on the plurality of fragment ions obtained in the HAD-MSn analysis step. This makes it possible to deal with precursor ions having various charges, and makes it easier to perform the structure estimation of the nucleic acid based on the mass spectrum.

Abstract: Provided is a macromolecular material that has self-healing properties, excellent stretchability, and a high degree of freedom in the design of stretchability, strength, and hardness, and that can be produced by a simple method; and also provided is a method for producing the same. The macromolecular material of the present invention comprises a polymer having a host group and a guest group. The host group is a monovalent group formed by removing one hydrogen atom or hydroxy group from a cyclodextrin derivative. The polymer is a polymer of a monomer mixture containing a host group-containing polymerizable monomer, a guest group-containing polymerizable monomer, and a third polymerizable monomer, and the third polymerizable monomer contains a (meth)acrylic ester compound. The host group-containing polymerizable monomer and the guest group-containing polymerizable monomer have a property of being dissolved in the third polymerizable monomer.

Abstract: In an ion analyzer dissociating an ion originating from a sample by bringing a radical into contact with the ion within a reaction chamber, a source gas from which the radical is to be generated is introduced into a generation chamber. A power supplier supplies electric power for generating an electric discharge within the generation chamber. A source-gas supplier supplies the source gas to the generation chamber. A controller controls the source-gas supplier and the power supplier to perform, in a switchable manner, a radical introduction mode where the electric power is supplied to the generation chamber while the source gas is supplied to the generation chamber for supplying the radical to the reaction chamber, and a source-gas-only introduction mode where the electric power is not supplied to the generation chamber while the source gas is supplied to the generation chamber for supplying the source gas to the reaction chamber.

Abstract: In an ion analyzer which dissociates an ion using a radical generated from a source gas, a gas supplier (26) supplies the source gas by selecting a gas from multiple kinds of gases and/or mixing two or more of those gases. The source gas is introduced into a generation chamber (210). A power supplier (25) supplies electric power for generating electric discharge within the generation chamber. A controller (3) controls those two suppliers as follows: When the radical is to be generated from a first gas through which electric discharge is relatively difficult to occur, the electric discharge is initiated by supplying electric power into the generation chamber while a second gas through which electric discharge occurs more easily is selected or mixed with the first gas and supplied to the generation chamber. After the electric discharge is initiated, the first gas is selectively supplied to the generation chamber.

Abstract: Disclosed are compounds of following formula (I): in which all symbols have the same meanings as the definitions described in the specification; or a salt thereof. The compounds or a salt thereof are useful as a prophylactic and/or therapeutic agent for cancer, Huntington's disease, Alzheimer's disease and the like.

Abstract: Provided are a method and a reagent for measuring an antibody against Helicobacter suis using a H. suis whole cell. A reagent for detecting an antibody that binds to a H. suis whole cell, of a specimen derived from a subject, the reagent comprising at least the H. suis whole cell and an anti-Ig antibody.

Abstract: Provided are a method and a reagent for measuring an antibody against Helicobacter suis using an outer membrane fraction of H. suis. A reagent for detecting an antibody that binds to a H. suis outer membrane fraction, or a protein contained in the outer membrane fraction, of a specimen derived from a subject, the reagent comprising at least the H. suis outer membrane fraction, or the protein contained in the outer membrane fraction, and an anti-Ig antibody.

Abstract: A composition suitable for injection molding, from which a molded product excellent in magnetic properties may be obtained, and an injection molded product excellent in magnetic properties are provided. A composition includes a magnetic powder and a thermoplastic resin, at least a part of the magnetic powder having a coating layer.

Abstract: A photosensitive resin composition including an ethylenically unsaturated compound, a resin having a polarity that increases by the action of an acid, and metal atoms, in which a total content of the metal atoms is from 1 ppt to 30 ppb with respect to a total mass of the photosensitive resin composition, and a content of the ethylenically unsaturated compound is from 0.0001% by mass to 1% by mass with respect to the total mass of the photosensitive resin composition, and a method for producing the same; and a resist film, a pattern forming method, and a method for manufacturing an electronic device, each of which uses the photosensitive resin composition.

Abstract: Provided are a diamantane compound with which an organic electroluminescent device that can exhibit excellent luminous efficiency characteristics, more preferably excellent drive voltage characteristics and excellent luminous efficiency characteristics, can be produced, and an organic electroluminescent device material containing the diamantane compound. Also provided is an organic electroluminescent device that can achieve luminous efficiency characteristics, more preferably drive voltage characteristics and luminous efficiency characteristics, at high levels. A diamantane compound has a group represented by formula (1) below and a group represented by formula (2) below. (In formula (1), carbon atoms of a diamantane ring are optionally substituted with an aryl group having 6 to 12 carbon atoms. In formula (1), * represents a bond, and a represents an integer of 1 to 6.

Abstract: A polarized waveguide filter is formed in which the polarized waveguide filter includes a first rectangular waveguide; a second rectangular waveguide; and a rectangular cavity resonator that has a first edge surface connected to an electromagnetic wave exit plane of the first rectangular waveguide via a coupling unit, and has a second edge surface facing the first edge surface and connected to an electromagnetic wave incident plane of the second rectangular waveguide via a coupling unit, and excites each of a TE10 mode and a TE20 mode of an electromagnetic wave, and the rectangular cavity resonator has two first wall surfaces and two second wall surfaces narrower in area than the first wall surfaces, and a protrusion that shifts a resonance frequency of the TE10 mode and a resonance frequency of the TE20 mode by respective amounts different from each other is provided on at least one of the two first wall surfaces, in such a way as to protrude outward from the rectangular cavity resonator.

Abstract: [TASK] In a reclining seat device, the behavior of the vehicle is accurately conveyed to a seated occupant without regard to the reclining angle of the seat back with respect to the seat cushion. [SOLUTION] The air cells 30 of the seat cushion 22 are vibrated with a higher intensity than those of the seat back 26 when the reclining angle is smaller than a predetermined value, and the air cells 30 of the seat back 26 are vibrated with a higher intensity than those of the seat cushion 22 when the reclining angle is equal to or greater than the predetermined value.

Abstract: SPINK2 mutant peptide conjugates are provided that inhibit KLK5. The KLK5 inhibitory peptide conjugates are Fc fusion peptides in which, in certain embodiments, the Fc region of the fusion peptides are the Fc region of human IgG1 or a fragment thereof. The KLK5 inhibitory peptide conjugates include an amino acid sequence of one of SEQ ID NOs: 34, 36, 38, 40, 42, 44, 46, 48, 96, 50, 52, 54, 56, 58, or 60. Pharmaceutical compositions that include the KLK5 inhibitory peptide conjugates useful for treating KLK5-related diseases are also provided.

Abstract: An ophthalmic system includes an acquiring unit which acquires a moving image of a subject's eye captured by an imaging apparatus that opposes a subject, an analyzing unit which specifies an analysis object region in the subject's eye based on the moving image and which analyzes a spatial and/or temporal distribution of information related to characteristics of a surface of the subject's eye in the analysis object region, an assessing unit which assesses a possibility of the subject's eye being affected by a predetermined ophthalmic disease based on the distribution of information related to the characteristics and which generates a classification result of classifying the subject's eye into a predetermined classification group related to the affection of the ophthalmic disease in accordance with a degree of the possibility, and a diagnosis support information generating unit which generates diagnosis support information.

Abstract: The method of operating a mass spectrometer includes: introducing precursor ions into a reaction chamber; generating radicals by generating plasma by supplying source gas and radio-frequency power to a radical generation chamber for a predetermined period by transmitting a predetermined control signal to a source gas supply part and a radio-frequency power supply part; generating product ions by introducing the radicals into the reaction chamber; measuring an intensity of light having a wavelength band including a wavelength of light emitted from the plasma inside the radical generation chamber; and determining and notifying an abnormality of the mass spectrometer on a basis of a fact that the intensity of the light exceeds a predetermined abnormality determination threshold value during a period other than the predetermined period.

Abstract: An information processing apparatus that comprises a processor configured to: acquire an image acquisition unit that acquires a medical image; extract one or more image feature values from the medical image; infer one or more diseases predicted from the medical image based on the one or more image feature values and a classification basis, the classification basis being a set of C basis vectors with each basis vector representing correlations between a disease of a set of C diseases and other diseases by using a vector of a certain dimension, wherein C is an integer of 2 or more; and output results identifying the one or more inferred diseases.

Abstract: First product ion spectrum data is acquired by dissociating a precursor ion derived from a sample component by collision between the precursor ion and an inert gas molecule to generate product ions, and detecting the product ions after separating the product ions according to a mass-to-charge ratio; second product ion spectrum data is acquired by dissociating the precursor ion by a reaction of the precursor ion with hydrogen radicals to generate product ions, and detecting the product ions after separating the product ions according to a mass-to-charge ratio; and a set of product ions having a predetermined mass difference is extracted in the first product ion spectrum data and the second product ion spectrum data.

Abstract: An ion analysis device 1 configured to generate and analyze product ions from precursor ions derived from a sample component includes: a reaction chamber 132 into which the precursor ions are introduced; a radical emitter 134 made of a predetermined kind of metal and disposed in the reaction chamber or a space communicating with the reaction chamber, at least a part of a surface of the radical emitter being oxidized or nitrided; a heating unit 20 configured to heat the radical emitter to a predetermined temperature; and separation detection units 135 and 136 configured to separate and detect, according to at least one of a mass-to-charge ratio and an ion mobility, product ions generated from the precursor ions by a reaction with radicals emitted from the radical emitter heated to the predetermined temperature.

Abstract: To provide a fundus information acquisition method that allows observation and photography to be conducted using an optical system of a simple and easy configuration without the need for accurate alignment of the imaging unit with a test eye even when there is a distance from the test eye. A fundus information acquisition method is provided with an infinity-corrected optical system that uses an imaging unit placed opposite an objective lens that causes light passing through the objective lens to form an image as part of a fundus image of a test eye, where at least a site defined by a range of a pupil of the test eye out of a cornea and a crystalline lens of the same test eye is used as the objective lens opposed to a fundus of the test eye.

Abstract: In a mass spectrometry method for generating product ions from a precursor ion derived from a sample component having a hydrocarbon chain and mass-analyzing the product ion, the precursor ion is irradiated with an oxygen radical or a hydroxy radical and a nitrogen oxide radical to generate product ions, the product ions are separated according to mass-to-charge ratio and the product ions are detected, and a structure of the hydrocarbon chain is inferred based on mass-to-charge ratio of the detected product ions.