Patents by Inventor Hideo Tsutsumi

Hideo Tsutsumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds
    Patent number: 5102877
    Abstract: 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxyic acids having antimicrobial activity have been prepared.
    Type: Grant
    Filed: April 12, 1990
    Date of Patent: April 7, 1992
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masayoshi Murata, Toshiyuki Chiba, Hideo Tsutsumi, Kohji Hattori, Satoru Kuroda, Hiroaki Ohtake, Fumiyuki Shirai
  • 3-pyrrolidinylthio-1-azabicyclo-(3.2.0)hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof
    Patent number: 5061804
    Abstract: 3-thio pyrrolidines are intermediates for carbapenams.
    Type: Grant
    Filed: March 6, 1990
    Date of Patent: October 29, 1991
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masayoshi Murata, Hideo Tsutsumi, Keiji Matsuda, Hohji Hattori, Takashi Nakajima
  • 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid derivatives and their preparation
    Patent number: 4983596
    Abstract: The invention relates to a compound of antimicrobial activity, of the formula: ##STR1## in which R.sup.1 is carboxy or protected carboxy,R.sup.2 is hydroxy(lower)alkyl or protected hydroxy(lower)alkyl,R.sup.3 is hydrogen or lower alkyl,R.sup.4 is 2-fluoroethyl, 2-chloroethyl, 2-fluoropropyl or 4-fluorobutyl,R.sup.5 is hydrogen, lower alkanimidoyl, unsubstituted lower cycloalkenyl or substituted by a group consisting of oxo and amino, or imino-protective group, andA is lower alkylene, or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: May 4, 1989
    Date of Patent: January 8, 1991
    Assignee: Fujisawa Pharmaceutical Company, Ltd.
    Inventors: Masayoshi Murata, Hideo Tsutsumi, Keiji Matsuda, Kohji Hattori, Takashi Nakajima
  • 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds
    Patent number: 4963544
    Abstract: 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene carboxylic acids substituted on the pyrrolidine by unsaturated heterocyclyl have been prepared.
    Type: Grant
    Filed: May 5, 1989
    Date of Patent: October 16, 1990
    Assignee: Fujisawa Pharmaceutical Company, Ltd.
    Inventors: Masayoshi Murata, Hideo Tsutsumi, Keiji Matsuda, Kohji Hattori, Takashi Nakajima
  • 3-pyrolidinylthio-1-azabicyclo-[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof
    Patent number: 4963543
    Abstract: 3-pyrrolidinylthio-1-azabicyclo[3.2.0]hepten-2-ene-2-carboxylic acid derivatives are prepared.
    Type: Grant
    Filed: November 17, 1987
    Date of Patent: October 16, 1990
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masayoshi Murata, Hideo Tsutsumi, Keiji Matsuda, Kohji Hattori, Takashi Nakajima
  • 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds
    Patent number: 4925838
    Abstract: 3-Pyrrolidinythio-1-azabicyclo [3.2.0]hept-2-ene-2-carboxylic acid compounds which have antimicrobial activity have been prepared.
    Type: Grant
    Filed: March 14, 1989
    Date of Patent: May 15, 1990
    Assignee: Fujisawa Pharmaceutical Company, Ltd.
    Inventors: Masayoshi Murata, Hideo Tsutsumi, Keiji Matsuda, Kohji Hattori, Takashi Nakajima
  • 3-pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds
    Patent number: 4921852
    Abstract: 3-Pyrrolidinylthio-1-azabicyclo [320] hept-2-ene-2-carboxylic acid anti-microbiotic compounds are prepared.
    Type: Grant
    Filed: November 24, 1987
    Date of Patent: May 1, 1990
    Assignee: Fujisawa Pharmaceutical Company, Ltd.
    Inventors: Masayoshi Murata, Hideo Tsutsumi, Keiji Matsuda, Kohji Hattori, Takashi Nakajima
  • 3-pyrrolidinylthio-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid compounds and antimicrobial activity thereof
    Patent number: 4822787
    Abstract: This invention consists of 3-pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds and their use as antimicrobial agents in the treatment of infectious diseases.
    Type: Grant
    Filed: November 5, 1987
    Date of Patent: April 18, 1989
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masayoshi Murata, Hideo Tsutsumi, Keiji Matsuda, Kohji Hattori, Takashi Nakajima
  • Aminoglycoside derivatives
    Patent number: 4656160
    Abstract: Aminoglycoside derivatives and pharmaceutically acceptable salts thereof which are useful as prophylactic and therapeutic agents for infectious diseases caused by pathogenic microorganisms, and a pharmaceutical composition comprising the same.
    Type: Grant
    Filed: November 18, 1985
    Date of Patent: April 7, 1987
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Takao Takaya, Nobuyoshi Yasuda, Hideo Tsutsumi, Keiji Matsuda
  • Kasugamycin derivatives, pharmaceutical compositions and method of use
    Patent number: 4554269
    Abstract: This invention relates to new aminoglycoside derivatives and pharmaceutically acceptable salts thereof. More particularly it relates to new aminoglycoside derivatives and pharmaceutically acceptable salts thereof which have anti-viral activity, and immuno-stimulating activity and pharmaceutical compositions comprising the same. In addition, this invention also relates to methods of preparing the aminoglycoside derivatives and salts thereof.
    Type: Grant
    Filed: January 24, 1984
    Date of Patent: November 19, 1985
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Takao Takaya, Nobuyoshi Yasuda, Hideo Tsutsumi, Keiji Matsuda
  • 1,4-Diaminocyclitol derivatives
    Patent number: 4504472
    Abstract: This invention relates to novel, 1,4-diaminocyclitol derivatives of antimicrobial and immunostimulating activity of the formula: ##STR1## wherein X.sup.1, X.sup.2 and X.sup.3 are each amino or protected amino, X.sup.4 is hydrogen or hydroxy,R.sup.1 is hydrogen or lower alkyl, andR.sup.2 is higher alkanoyl permissably substituted with hydroxy, amino, azido, epoxy, protected hydroxy or protected amino, or higher alkenoyl, or higher alkylcarbanoyl,and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: February 28, 1983
    Date of Patent: March 12, 1985
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Takao Takaya, Hideo Tsutsumi, Nobuyuki Yasuda, Keiji Matsuda
  • Aminoglycoside derivatives
    Patent number: 4493831
    Abstract: Aminoglycoside derivatives and pharmaceutically acceptable salts thereof which are useful as prophylactic and therapeutic agents for infectious diseases caused by pathogenic microorganisms, processes for the preparation thereof and a pharmaceutical composition comprising the same.
    Type: Grant
    Filed: September 30, 1983
    Date of Patent: January 15, 1985
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Takao Takaya, Nobuyoshi Yasuda, Hideo Tsutsumi, Keiji Matsuda