Patents by Inventor Hideo Utsumi
Hideo Utsumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240290067Abstract: An analysis system in which an image component part is provided, and the image component part includes a memory part and an image operation part, the memory part stores at least core image pixel information and operating image pixel information, the core image pixel information and the operating image pixel information include the same sample and the same analysis target region and include a predetermined number of pixels imaged by different imaging systems, the operating image pixel information includes analysis information and is image pixel information with luminance and/or resolution lower than the core image pixel information, and the image operation part performs operations including Hadamard product for at least one or more pieces of the core image pixel information and at least one or more pieces of the operating image pixel information so as to build a new created image pixel information.Type: ApplicationFiled: June 23, 2022Publication date: August 29, 2024Inventor: Hideo UTSUMI
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Publication number: 20160216351Abstract: The object of the invention is to provide a method for detecting an oxidation/reduction reaction of a molecule in a lipophilic portion and visualizing the reaction. This is a method for detecting an oxidation/reduction reaction of a molecule that undergoes a free-radical reaction in a lipid environment, the method including: a step in which a magnetic resonance method is applied to a living body or sample to be examined and a proton image of the molecule that undergoes a free-radical reaction in a lipid environment is thereby obtained; and a step in which the proton image is examined for the image intensity of the living body or sample.Type: ApplicationFiled: May 29, 2014Publication date: July 28, 2016Applicant: Kyushu University, National University CorporationInventors: Hideo UTSUMI, Fuminori HYODO, Shinji Ito
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Publication number: 20160116562Abstract: The measurement apparatus and the MRI apparatus are provided with a magnet, which forms a specified static magnetic field, and a magnetic field gradient coil for applying a gradient magnetic field on the static magnetic field, and the magnetic field gradient coil is a structure that is separated from the magnet and is configured to be movable relative to the magnet. The MRI apparatus is characterized in that MRI images of a subject are acquired while the magnetic field gradient coil is moving relative to the magnet.Type: ApplicationFiled: June 3, 2014Publication date: April 28, 2016Inventors: Hideo UTSUMI, Ryoma KOBAYASHI
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Publication number: 20150168510Abstract: A magnetic field application device capable of applying a magnetic field to an object for a sufficient time is provided. A first magnetic circuit which is one of the two magnetic circuits provided to the magnetic field application device is provided with two magnetic poles of a first magnetic pole 1 and a second magnetic pole 2. The first magnetic pole 1 is provided with a first yoke 11 that is arc-shaped in planar view, a first magnet 13 that is arc-shaped in planar view and a first magnetic pole piece 15. On the other hand, the second magnetic pole 2 is provided with a second yoke 21 that is arc-shaped in planar view, a second magnet 23 that is arc-shaped in planar view and a second magnetic pole piece 25. The first magnetic pole piece 15 and the second magnetic pole piece 25 are disposed so as to be opposed to each other while being separated from each other.Type: ApplicationFiled: June 26, 2013Publication date: June 18, 2015Inventors: Hideo Utsumi, Kazuhiro Ichikawa, Fuminori Hyodo, Tatsuya Naganuma, Atsushi Iikura, Hidenori Kajiwara, Eiji Sugiyama, Masaaki Aoki
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Patent number: 8896311Abstract: A measuring instrument and a measurement method which measures, using magnetic resonance, images such as a functional image, a morphologic image of an object to be measured eliminate the influences of the moving speed of the object to be measured during moving, thereby obtaining a precise measured image.Type: GrantFiled: March 25, 2010Date of Patent: November 25, 2014Assignee: Kyushu University, National University CorporationInventors: Hideo Utsumi, Kazuhiro Ichikawa, Tetsuhiko Takahashi
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Patent number: 8722420Abstract: Provided is a method for the real-time visualization of an endogenous biomolecule to clarify the mechanisms of various diseases and enable diagnosis and treatment of these diseases. Specifically provided is a novel method for visualizing an endogenous biomolecule by using a magnetic resonance method (including Overhauser MRI and the electron spin resonance method). The aforesaid visualization method, whereby an endogenous biomolecule is visualized on a real-time basis, comprises: a step for treating a living organism to be examined by a magnetic resonance method and thus acquiring data of the endogenous biomolecule; a step for processing the data of the endogenous biomolecule thus obtained to give imaging data; and a step for displaying the imaging data thus obtained.Type: GrantFiled: October 29, 2010Date of Patent: May 13, 2014Assignee: Kyushu University, National University CorporationInventors: Hideo Utsumi, Fuminori Hyodo, Kazuhiro Ichikawa
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Patent number: 8532740Abstract: A measurement device and measurement method make it possible to eliminate the load generated by stopping on a measurement subject that is moved among multiple magnetic field generating devices. The measurement device includes a first external magnetic field generating device that generates a magnetic field of a set size, a second external magnetic field generating device that generates a magnetic field of a size that differs from that of the magnetic field of the first external magnetic field generating device, a rotating table that causes the subject of measurement to pass in sequence through the magnetic fields of the first and second external magnetic field generating devices by causing the subject of measurement to move rotationally, and an OMRI measurement processing part and MRI measurement processing part that measures images such as functional images or structural images of the subject of measurement while it is being moved rotationally by the rotating table.Type: GrantFiled: July 7, 2009Date of Patent: September 10, 2013Assignee: Kyushi UniversityInventors: Kazuhiro Ichikawa, Hideo Utsumi
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Patent number: 8513417Abstract: The problem to be solved by the present invention is to provide a highly-versatile method for producing a nitroxyl radical derivative, in which position-2 and position-6 in a TEMPO-based compound can be easily substituted, and further, a method for producing a nitroxyl radical derivative, in which a nitrogen nucleus is labeled with 15N. The above-described problem can be solved by reacting a triacetoneamine derivative with ketone or aldehyde in the presence of ammonium salt or a 15N-labeled compound thereof to obtain a 2,6-substituted-4-piperidone derivative.Type: GrantFiled: January 30, 2008Date of Patent: August 20, 2013Assignee: Kyushu University, National University CorporationInventors: Hideo Utsumi, Kiyoshi Sakai, Kenichi Yamada
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Publication number: 20120276644Abstract: Provided is a method for the real-time visualization of an endogenous biomolecule to clarify the mechanisms of various diseases and enable diagnosis and treatment of these diseases. Specifically provided is a novel method for visualizing an endogenous biomolecule by using a magnetic resonance method (including Overhauser MRI and the electron spin resonance method). The aforesaid visualization method, whereby an endogenous biomolecule is visualized on a real-time basis, comprises: a step for treating a living organism to be examined by a magnetic resonance method and thus acquiring data of the endogenous biomolecule; a step for processing the data of the endogenous biomolecule thus obtained to give imaging data; and a step for displaying the imaging data thus obtained.Type: ApplicationFiled: October 29, 2010Publication date: November 1, 2012Applicant: Kyushu University, National University CorporationInventors: Hideo Utsumi, Fuminori Hyodo, Kazuhiro Ichikawa
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Publication number: 20120068705Abstract: A measuring instrument and a measurement method which measures, using magnetic resonance, images such as a functional image, a morphologic image of an object to be measured eliminate the influences of the moving speed of the object to be measured during moving, thereby obtaining a precise measured image.Type: ApplicationFiled: March 25, 2010Publication date: March 22, 2012Inventors: Hideo Utsumi, Kazuhiro Ichikawa, Tetsuhiko Takahashi
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Publication number: 20110112395Abstract: A measurement device and measurement method make it possible to eliminate the load generated by stopping on a measurement subject that is moved among multiple magnetic field generating devices. The measurement device includes a first external magnetic field generating device that generates a magnetic field of a set size, a second external magnetic field generating device that generates a magnetic field of a size that differs from that of the magnetic field of the first external magnetic field generating device, a rotating table that causes the subject of measurement to pass in sequence through the magnetic fields of the first and second external magnetic field generating devices by causing the subject of measurement to move rotationally, and an OMRI measurement processing part and MRI measurement processing part that measures images such as functional images or structural images of the subject of measurement while it is being moved rotationally by the rotating table.Type: ApplicationFiled: July 7, 2009Publication date: May 12, 2011Inventors: Kazuhiro Ichikawa, Hideo Utsumi
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Publication number: 20100076190Abstract: The problem to be solved by the present invention is to provide a highly-versatile method for producing a nitroxyl radical derivative, in which position-2 and position-6 in a TEMPO-based compound can be easily substituted, and further, a method for producing a nitroxyl radical derivative, in which a nitrogen nucleus is labeled with 15N. The above-described problem can be solved by reacting a triacetoneamine derivative with ketone or aldehyde in the presence of ammonium salt or a 15N-labeled compound thereof to obtain a 2,6-substituted-4-piperidone derivative.Type: ApplicationFiled: January 30, 2008Publication date: March 25, 2010Inventors: Hideo Utsumi, Kiyoshi Sakai, Kenichi Yamada
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Patent number: 6239145Abstract: Nitroxyl compounds represented by general formula (I) which are usable in acquiring information about active oxygen or in vivo free radicals as biological images such as magnetic resonance images or magnetoencephalograms, wherein A represents hydrogen or —L—(CH2)n—OCOR (wherein L represents —COO— or -alkylene-COO—; and R represents C1-4 alkyl); R1, R2, R3, and R4 represent each C1-4 alkyl; and n is a number of from 1 to 4. Drugs and reagents containing the above compounds are usable in preventing, treating or diagnosing ischemic diseases, digestive diseases, cancer, cranial nervous diseases accompanied by nerve degeneration, inflammation, cataracts, or drug-induced organopathy.Type: GrantFiled: December 27, 1999Date of Patent: May 29, 2001Assignee: Daiitchi Radioisotope Laboratories, Ltd.Inventors: Hideo Utsumi, Hiroaki Sano, Masaichi Naruse, Takashi Igarashi, Tetsuo Oi