Abstract: The present disclosure includes a system for use in the treatment of cancer, the system comprising an extracorporeal circulation device comprising a blood circuit and a blood pump to collect and return blood of a subject, and a light irradiation device to irradiate the blood circuit with light, wherein a photosensitive substance is administered to the subject prior to blood collection, or added to blood collected from the subject prior to light irradiation, the blood collected from the subject and irradiated with light is returned to the subject, and the light has an irradiation energy density of 2.5 to 300 J/cm2.

Abstract: Provided is a method for measuring anti-drug antibodies ADAs appearing in a patient receiving molecular-targeted therapy in a simpler and more accurate manner.

Abstract: Provided is a method for measuring ADAs appearing in a patient receiving molecular-targeted therapy with a drug or the like in a simpler and more accurate manner. A method for measuring anti-drug antibodies (ADAs) in an analyte to be measured, the method comprising: (1) a step of providing a sample comprising an analyte to be measured for ADAs, the step comprising adding a corresponding drug to an analyte to be measured for ADAs to prepare a sample with a drug-ADAs immune complex formed; (2) a step of contacting the sample prepared in step (1) with a carrier coated with complement Clq, anti-C3d antibody, or anti-Clq antibody; (3) a step of contacting a labeled or non-labeled antibody to a drug corresponding to the ADAs with the coated carrier prepared in step (2); and (4) a step of quantifying the drug-ADAs immune complex binding to the complement Clq, anti-C3d antibody, or anti-Clq antibody.