Patents by Inventor Hideto FUJIWARA
Hideto FUJIWARA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230265073Abstract: The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin V1a and V2 antagonisms, and medical uses thereof. In the formula, R1 is optionally substituted C1-6 alkyl, etc.; L is —C(?O)—NH—, etc.; Ring A1 is a hydrocarbon ring, etc.; Ring A2 is a hydrocarbon ring, etc.; and each of Rings A1 and A2 may have at least one substituent.Type: ApplicationFiled: April 27, 2023Publication date: August 24, 2023Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Keizo KAN, Masatoshi TAKUWA, Hirotaka TANAKA, Hideto FUJIWARA, Hokuto YAMABE, Satoshi MATSUDA, Kazuhiro OHDACHI, Taiki HANARI, Yasuhiro MENJO, Tatsuya URUSHIMA, Shigekazu FUJITA
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Patent number: 11673878Abstract: The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin V1a and V2 antagonisms, and medical uses thereof. In the formula, R1 is optionally substituted C1-6 alkyl, etc.; L is —C(?O)—NH—, etc.; Ring A1 is a hydrocarbon ring, etc.; Ring A2 is a hydrocarbon ring, etc.; and each of Rings A1 and A2 may have at least one substituent.Type: GrantFiled: November 24, 2020Date of Patent: June 13, 2023Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Keizo Kan, Masatoshi Takuwa, Hirotaka Tanaka, Hideto Fujiwara, Hokuto Yamabe, Satoshi Matsuda, Kazuhiro Ohdachi, Taiki Hanari, Yasuhiro Menjo, Tatsuya Urushima, Shigekazu Fujita
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Patent number: 11466016Abstract: The invention provides new pyrazine derivatives of formula (I): or a tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the substituents are as defined herein. The invention also provides pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.Type: GrantFiled: March 1, 2019Date of Patent: October 11, 2022Assignees: OTSUKA PHARMACEUTICAL CO., LTD., TAIHO PHARMACEUTICAL CO., LTD.Inventors: Christopher Norbert Johnson, Ildiko Maria Buck, Gianni Chessari, James Edward Harvey Day, Hideto Fujiwara, Christopher Charles Frederick Hamlett, Steven Douglas Hiscock, Rhian Sara Holvey, Steven Howard, John Walter Liebeschuetz, Nicholas John Palmer, Jeffrey David St Denis, David Geoffrey Twigg, Andrew James Woodhead
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Publication number: 20210107908Abstract: The invention provides new pyrazine derivatives of formula (I): or a tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the substituents are as defined herein. The invention also provides pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.Type: ApplicationFiled: March 1, 2019Publication date: April 15, 2021Applicants: OTSUKA PHARMACEUTICAL CO., LTD., TAIHO PHARMACEUTICAL CO., LTD.Inventors: Christopher Norbert JOHNSON, Ildiko Maria BUCK, Gianni CHESSARI, James Edward Harvey DAY, Hideto FUJIWARA, Christopher Charles Frederick HAMLETT, Steven Douglas HISCOCK, Rhian Sara HOLVEY, Steven HOWARD, John Walter LIEBESCHUETZ, Nicholas John PALMER, Jeffrey David ST DENIS, David Geoffrey TWIGG, Andrew James WOODHEAD
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Publication number: 20210078976Abstract: The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin V1a and V2 antagonisms, and medical uses thereof. In the formula, R1 is optionally substituted C1-6 alkyl, etc.; L is —C(?O)—NH—, etc.; Ring A1 is a hydrocarbon ring, etc.; Ring A2 is a hydrocarbon ring, etc.; and each of Rings A1 and A2 may have at least one substituent.Type: ApplicationFiled: November 24, 2020Publication date: March 18, 2021Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Keizo KAN, Masatoshi TAKUWA, Hirotaka TANAKA, Hideto FUJIWARA, Hokuto YAMABE, Satoshi MATSUDA, Kazuhiro OHDACHI, Taiki HANARI, Yasuhiro MENJO, Tatsuya URUSHIMA, Shigekazu FUJITA
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Patent number: 10889570Abstract: The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin V1a and V2 antagonisms, and medical uses thereof. In the formula, R1 is optionally substituted C1-6 alkyl, etc.; L is —C(?O)—NH—, etc.; Ring A1 is a hydrocarbon ring, etc.; Ring A2 is a hydrocarbon ring, etc.; and each of Rings A1 and A2 may have at least one substituent.Type: GrantFiled: June 29, 2018Date of Patent: January 12, 2021Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Keizo Kan, Masatoshi Takuwa, Hirotaka Tanaka, Hideto Fujiwara, Hokuto Yamabe, Satoshi Matsuda, Kazuhiro Ohdachi, Taiki Hanari, Yasuhiro Menjo, Tatsuya Urushima, Shigekazu Fujita
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Publication number: 20190389838Abstract: The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin V1a and V2 antagonisms, and medical uses thereof. In the formula, R1 is optionally substituted C1-6 alkyl, etc.; L is —C(?O)—NH—, etc.; Ring A1 is a hydrocarbon ring, etc.; Ring A2 is a hydrocarbon ring, etc.; and each of Rings A1 and A2 may have at least one substituent.Type: ApplicationFiled: June 29, 2018Publication date: December 26, 2019Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Keizo KAN, Masatoshi TAKUWA, Hirotaka TANAKA, Hideto FUJIWARA, Hokuto YAMABE, Satoshi MATSUDA, Kazuhiro OHDACHI, Taiki HANARI, Yasuhiro MENJO, Tatsuya URUSHIMA, Shigekazu FUJITA
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Patent number: 10495118Abstract: Provided is a hydraulic drive device, wherein the hydraulic drive device is provided with: a cylinder (101); a rod (103); a piston (102); a hydraulic pump (107); a tank (113); a valve (106) that can be switched between a positive state of connecting the hydraulic pump (107) and a head chamber (101h) and connecting a rod chamber (101r) and the tank (113), and a negative state of connecting the hydraulic pump (107) and the rod chamber (101r) and connecting the head chamber (101h) and the tank (113); and a confluence channel (114) at which, when the valve (106) is in the positive state, at least a portion of hydraulic oil going from the rod chamber (101r) to the tank (113) is merged into hydraulic oil going from the hydraulic pump (107) to the head chamber (101h).Type: GrantFiled: May 30, 2016Date of Patent: December 3, 2019Assignee: Kobe Steel, Ltd.Inventors: Toru Eguchi, Yoshiharu Nishida, Naofumi Kanei, Hideto Fujiwara
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Patent number: 10281361Abstract: A tire uniformity tester having: a spindle capable of rotating while holding a tire; a drum; a pressing mechanism that rotatably supports the drum and makes it possible to press a tire attached to the spindle into the drum through the relative movement of the drum and spindle; a uniformity measurement unit for measuring the uniformity of the tire during forward rotation and reverse rotation; and a control device. The control device controls the driving of the rotation of the spindle and the relative positions of the spindle and drum so that when the rotation direction of the spindle is reversed, the spindle and drum are separated from each other such that the spindle rotation speed reaches zero in a state in which the outer peripheral surface of the drum and the tire tread surface are not in contact with each other.Type: GrantFiled: July 23, 2015Date of Patent: May 7, 2019Assignee: Kobe Steel, Ltd.Inventor: Hideto Fujiwara
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Publication number: 20180202467Abstract: Provided is a hydraulic drive device, wherein the hydraulic drive device is provided with: a cylinder (101); a rod (103); a piston (102); a hydraulic pump (107); a tank (113); a valve (106) that can be switched between a positive state of connecting the hydraulic pump (107) and a head chamber (101h) and connecting a rod chamber (101r) and the tank (113), and a negative state of connecting the hydraulic pump (107) and the rod chamber (101r) and connecting the head chamber (101h) and the tank (113); and a confluence channel (114) at which, when the valve (106) is in the positive state, at least a portion of hydraulic oil going from the rod chamber (101r) to the tank (113) is merged into hydraulic oil going from the hydraulic pump (107) to the head chamber (101h).Type: ApplicationFiled: May 30, 2016Publication date: July 19, 2018Applicant: Kabushiki Kaisha Kobe Seiko Sho (Kobe Steel, Ltd.)Inventors: Toru EGUCHI, Yoshiharu NISHIDA, Naofumi KANEI, Hideto FUJIWARA
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Patent number: 9834408Abstract: An elevator call registering system includes: a responder configure to store therein user identification information; an interrogator configured to broadcast interrogator identification information, an authentication control apparatus configured to compare the user identification information read out from the interrogator with stored user identification information, and an elevator control apparatus.Type: GrantFiled: September 23, 2014Date of Patent: December 5, 2017Assignee: MITSUBISHI ELECTRIC CORPORATIONInventor: Hideto Fujiwara
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Publication number: 20170234774Abstract: A tire uniformity tester having: a spindle capable of rotating while holding a tire; a drum; a pressing mechanism that rotatably supports the drum and makes it possible to press a tire attached to the spindle into the drum through the relative movement of the drum and spindle; a uniformity measurement unit for measuring the uniformity of the tire during forward rotation and reverse rotation; and a control device. The control device controls the driving of the rotation of the spindle and the relative positions of the spindle and drum so that when the rotation direction of the spindle is reversed, the spindle and drum are separated from each other such that the spindle rotation speed reaches zero in a state in which the outer peripheral surface of the drum and the tire tread surface are not in contact with each other.Type: ApplicationFiled: July 23, 2015Publication date: August 17, 2017Applicant: Kabushiki Kaisha Kobe Seiko Sho (Kobe Steel, Ltd.)Inventor: Hideto FUJIWARA
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Patent number: 9541628Abstract: A position detection system includes a responder configured to be carried by a user; interrogators, and a position detection unit configured to detect the user.Type: GrantFiled: September 23, 2014Date of Patent: January 10, 2017Assignee: MITSUBISHI ELECTRIC CORPORATIONInventor: Hideto Fujiwara
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Publication number: 20150226832Abstract: A position detection system includes a responder configured to be carried by a user; interrogators, and a position detection unit configured to detect the user.Type: ApplicationFiled: September 23, 2014Publication date: August 13, 2015Applicant: Mitsubishi Electric CorporationInventor: Hideto FUJIWARA
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Publication number: 20150210505Abstract: An elevator call registering system includes: a responder configure to store therein user identification information; an interrogator configured to broadcast interrogator identification information, an authentication control apparatus configured to compare the user identification information read out from the interrogator with stored user identification information, and an elevator control apparatus.Type: ApplicationFiled: September 23, 2014Publication date: July 30, 2015Applicant: Mitsubishi Electric CorporationInventor: Hideto FUJIWARA