Patents by Inventor Hidetoshi Masumoto

Hidetoshi Masumoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing mixed cell population of cardiomyocytes and vascular cells from induced pluripotent stem cell
    Patent number: 9764063
    Abstract: The present invention provides: a method for producing mixed cells comprising cardiomyocytes, endothelial cells and mural cells from induced pluripotent stem cells, the method comprising (a) a step of producing cardiomyocytes from induced pluripotent stem cells and (b) a step of culturing the cardiomyocytes in the presence of VEGF; and a therapeutic agent for heart diseases, comprising the mixed cells produced by the method.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: September 19, 2017
    Assignee: IHEART JAPAN CORPORATION
    Inventors: Jun Yamashita, Hidetoshi Masumoto
  • Method for producing myocardial sheet from embryonic stem cell
    Patent number: 9623052
    Abstract: The present invention provides a method for producing a myocardial sheet using a group of cells derived from embryonic stem cells. This method is characterized by mixing Flk/KDR positive cells, cardiomyocytes, endothelial cells, and mural cells, all derived from embryonic stem cells, and culturing the mixed cells. Furthermore, the myocardial sheet can be used as a therapeutic agent for heart diseases since VEGF is released from the sheet.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: April 18, 2017
    Assignees: Tokyo Women's Medical University, Kyoto University
    Inventors: Teruo Okano, Tatsuya Shimizu, Jun Yamashita, Hidetoshi Masumoto
  • METHOD FOR PRODUCING MIXED CELL POPULATION OF CARDIOMYOCYTES AND VASCULAR CELLS FROM INDUCED PLURIPOTENT STEM CELL
    Publication number: 20150297794
    Abstract: The present invention provides: a method for producing mixed cells comprising cardiomyocytes, endothelial cells and mural cells from induced pluripotent stem cells, the method comprising (a) a step of producing cardiomyocytes from induced pluripotent stem cells and (b) a step of culturing the cardiomyocytes in the presence of VEGF; and a therapeutic agent for heart diseases, comprising the mixed cells produced by the method.
    Type: Application
    Filed: March 15, 2013
    Publication date: October 22, 2015
    Applicant: IHEART JAPAN CORPORATION
    Inventors: Jun YAMASHITA, Hidetoshi MASUMOTO
  • METHOD FOR PRODUCING MYOCARDIAL SHEET FROM EMBRYONIC STEM CELLS
    Publication number: 20140056859
    Abstract: The present invention provides a method for producing a myocardial sheet using a group of cells derived from embryonic stem cells. This method is characterized by mixing Flk/KDR positive cells, cardiomyocytes, endothelial cells, and mural cells, all derived from embryonic stem cells, and culturing the mixed cells. Furthermore, the myocardial sheet can be used as a therapeutic agent for heart diseases since VEGF is released from the sheet.
    Type: Application
    Filed: March 30, 2013
    Publication date: February 27, 2014
    Inventors: Teruo Okano, Tatsuya Shimizu, Jun Yamashita, Hidetoshi Masumoto