Patents by Inventor Hidetoshi Morita

Hidetoshi Morita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180245138
    Abstract: Provided is a diagnosis method for an autoimmune disease, including a step of measuring the relative abundances of bacteria included in a fecal sample collected from a test subject; and a step of performing the following (1), for example: (1) in a case in which relative abundance of a bacterium whose nucleotide sequence of 16S ribosomal RNA gene has an identity of 99% or higher with nucleotide sequence set forth in SEQ ID NO:3 or SEQ ID NO:4, is large compared to the relative abundance in healthy subject, determining that the test subject has contracted, or has a high risk of contracting, the autoimmune disease.
    Type: Application
    Filed: August 26, 2016
    Publication date: August 30, 2018
    Inventors: Takashi YAMAMURA, Masahira HATTORI, Hidetoshi MORITA, Sachiko MIYAKE
  • Patent number: 10058578
    Abstract: Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.
    Type: Grant
    Filed: April 14, 2017
    Date of Patent: August 28, 2018
    Assignees: The University of Tokyo, School Corporation, Azabu Veterinary Medicine Educational Institution
    Inventors: Kenya Honda, Koji Atarashi, Takeshi Tanoue, Masahira Hattori, Hidetoshi Morita
  • Patent number: 10052353
    Abstract: Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: August 21, 2018
    Assignees: The University of Tokyo, School Corporation, Azabu Veterinary Medicine Educational Institute
    Inventors: Kenya Honda, Koji Atarashi, Takeshi Tanoue, Masahira Hattori, Hidetoshi Morita
  • Publication number: 20180185421
    Abstract: The present invention provides a composition for preventing or treating a graft-versus-host disease, the composition comprising a fecal microbiota.
    Type: Application
    Filed: August 28, 2017
    Publication date: July 5, 2018
    Inventors: Kazuhiko KAKIHANA, Masahira Hattori, Kenya Honda, Hiroyoshi Nishikawa, Hidetoshi Morita, Kozue Takeshita
  • Patent number: 9977686
    Abstract: An ECU (Electronic Control Unit) evaluation apparatus, for use in vehicle design, allocates functions appropriately to respective ECUs of a vehicle. The function allocation can be performed based on user-specified priority aspect(s) in conjunction with stored information concerning the respective functions and information concerning the ECUs, such as installation positions on the vehicle, mechanical and electrical specifications of component parts of ECUs, etc.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: May 22, 2018
    Assignee: DENSO CORPORATION
    Inventors: Tomoya Tokunaga, Hidetoshi Morita
  • Publication number: 20170216378
    Abstract: Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.
    Type: Application
    Filed: April 14, 2017
    Publication date: August 3, 2017
    Applicants: The University of Tokyo, School Corporation, Azabu Veterinary Medicine Educational Institution
    Inventors: KENYA HONDA, Koji Atarashi, Takeshi Tanoue, Masahira Hattori, Hidetoshi Morita
  • Publication number: 20170209502
    Abstract: Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.
    Type: Application
    Filed: March 28, 2017
    Publication date: July 27, 2017
    Applicants: The University of Tokyo, School Corporation, Azabu Veterinary Medicine Educational Institution
    Inventors: Kenya Honda, Koji Atarashi, Takeshi Tanoue, Masahira Hattori, Hidetoshi Morita
  • Patent number: 9649345
    Abstract: Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: May 16, 2017
    Assignees: The University of Tokyo, School Corporation, Azabu Veterinary Medicine Educational Institution
    Inventors: Kenya Honda, Koji Atarashi, Takeshi Tanoue, Masahira Hattori, Hidetoshi Morita
  • Patent number: 9642881
    Abstract: Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: May 9, 2017
    Assignees: The University of Tokyo, School Corporation, Azabu Veterinary Medicine Educational Institution
    Inventors: Kenya Honda, Koji Atarashi, Takeshi Tanoue, Masahira Hattori, Hidetoshi Morita
  • Publication number: 20170028061
    Abstract: Strains of human-derived bacteria have been obtained from complex fecal samples and shown to induce accumulation of Th17 cells in the intestine and promote immune functions. Pharmaceutical compositions containing these bacteria can be used as anti-infectives and as adjuvants in mucosal vaccines.
    Type: Application
    Filed: April 10, 2015
    Publication date: February 2, 2017
    Applicants: RIKEN, The University of Tokyo, School Corporation, Azabu Veterinary Medicine Educational Institution
    Inventors: Kenya Honda, Koji Atarashi, Masahira Hattori, Hidetoshi Morita
  • Publication number: 20160193257
    Abstract: Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.
    Type: Application
    Filed: February 9, 2016
    Publication date: July 7, 2016
    Applicants: The University of Tokyo, School Corporation, Azabu Veterinary Medicine Educational Institution
    Inventors: Kenya Honda, Koji Atarashi, Takeshi Tanoue, Masahira Hattori, Hidetoshi Morita
  • Publication number: 20160193256
    Abstract: Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.
    Type: Application
    Filed: February 9, 2016
    Publication date: July 7, 2016
    Applicants: The University of Tokyo, School Corporation, Azabu Veterinary Medicine Educational Institution
    Inventors: Kenya Honda, Koji Atarashi, Takeshi Tanoue, Masahira Hattori, Hidetoshi Morita
  • Patent number: 9260066
    Abstract: A vehicle-mounted network system includes a plurality of electronic control units (ECUs) communicatively connected to a communication path of a vehicle-mounted network, each of which is configured to selectively perform a normal mode of operation and a sleep mode, and a management apparatus. The plurality of ECUs are configured to be individually powered on and off by a power supply relay of the management apparatus. The management apparatus is configured to acquire information indicative of a vehicle situation and determine a scene from the acquired information, determine control contents for powering on or off at least one specific ECU, of the plurality of ECUs, corresponding to the determined scene, if any, and power on or off the at least one specific ECU based on the determined control contents.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: February 16, 2016
    Assignee: DENSO CORPORATION
    Inventors: Tomoya Tokunaga, Hidetoshi Morita
  • Publication number: 20150112510
    Abstract: A vehicle-mounted network system includes a plurality of electronic control units (ECUs) communicatively connected to a communication path of a vehicle-mounted network, each of which is configured to selectively perform a normal mode of operation and a sleep mode, and a management apparatus. The plurality of ECUs are configured to be individually powered on and off by a power supply relay of the management apparatus. The management apparatus is configured to acquire information indicative of a vehicle situation and determine a scene from the acquired information, determine control contents for powering on or off at least one specific ECU, of the plurality of ECUs, corresponding to the determined scene, if any, and power on or off the at least one specific ECU based on the determined control contents.
    Type: Application
    Filed: October 23, 2014
    Publication date: April 23, 2015
    Inventors: Tomoya TOKUNAGA, Hidetoshi MORITA
  • Publication number: 20140352142
    Abstract: A wiring harness evaluation apparatus includes a functional allocation means which allocates functions realized by a plurality of ECUs installed in a vehicle to the ECUs, a routing path setting means which sets a routing path of a wiring harness in conformity with the allocation by the functional allocation means, a component selection means which selects components for configuring the wiring harness in conformity with the routing path set by the routing path setting means, and an evaluation value calculation means which calculates an evaluation value for at least one of a total weight of the components, total cost of the components, and total length of electric wires configuring the wiring harness on the basis of information on the components selected by the component selection means.
    Type: Application
    Filed: June 2, 2014
    Publication date: December 4, 2014
    Applicant: DENSO CORPORATION
    Inventors: Tomoya TOKUNAGA, Hidetoshi MORITA
  • Publication number: 20140350911
    Abstract: An ECU (Electronic Control Unit) evaluation apparatus, for use in vehicle design, allocates functions appropriately to respective ECUs of a vehicle. The function allocation can be performed based on user-specified priority aspect(s) in conjunction with stored information concerning the respective functions and information concerning the ECUs, such as installation positions on the vehicle, mechanical and electrical specifications of component parts of ECUs, etc.
    Type: Application
    Filed: May 23, 2014
    Publication date: November 27, 2014
    Applicant: DENSO CORPORATION
    Inventors: Tomoya TOKUNAGA, Hidetoshi MORITA
  • Publication number: 20140341921
    Abstract: Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.
    Type: Application
    Filed: November 29, 2012
    Publication date: November 20, 2014
    Applicants: The University of Tokyo, School Corporation , Azabu Veterinary Medicine Educational Institution
    Inventors: Kenya Honda, Koji Atarashi, Takeshi Tanoue, Masahira Hattori, Hidetoshi Morita
  • Patent number: 8877483
    Abstract: An accelerating agent for elimination of dioxins which comprises, as an active ingredient, a microorganism having an activity of accelerating elimination of dioxins in the body to the outside of the body.
    Type: Grant
    Filed: May 30, 2003
    Date of Patent: November 4, 2014
    Assignee: Calpis Co., Ltd.
    Inventors: Tadashi Shinoda, Akihiro Masuyama, Hidetoshi Morita, Hiroshi Yoshikawa
  • Patent number: 8637000
    Abstract: An anti-obesity agent containing, as an active ingredient, a microorganism which belongs to the species Lactobacillus reuteri and is capable of producing lipases having the amino acid sequences respectively depicted in SEQ ID NO: 1, 3 or 5 or amino acid sequences having deletion, substitution or addition of one or more amino acids in the amino acid sequences respectively depicted in SEQ ID NO: 1, 3 or 5. The anti-obesity agent enables a patient to take a normal meal yet preventing the absorption of a fat into the body which is the primary cause of obesity.
    Type: Grant
    Filed: June 1, 2011
    Date of Patent: January 28, 2014
    Assignee: Nestec S.A.
    Inventors: Hidetoshi Morita, Toshio Masaoka, Takehito Suzuki
  • Patent number: 8637001
    Abstract: An anti-obesity agent containing, as an active ingredient, a microorganism which belongs to the species Lactobacillus reuteri and is capable of producing lipases having the amino acid sequences respectively depicted in SEQ ID NO: 1, 3 or 5 or amino acid sequences having deletion, substitution or addition of one or more amino acids in the amino acid sequences respectively depicted in SEQ ID NO: 1, 3 or 5. The anti-obesity agent enables a patient to take a normal meal yet preventing the absorption of a fat into the body which is the primary cause of obesity.
    Type: Grant
    Filed: June 6, 2011
    Date of Patent: January 28, 2014
    Assignee: Nestec S.A.
    Inventors: Hidetoshi Morita, Toshio Masaoka, Takehito Suzuki