Patents by Inventor Hidetoshi Shimizu

Hidetoshi Shimizu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11911366
    Abstract: A method of treating an oxidative stress disease includes orally or intragastrically administering, to a subject in need thereof, a pharmaceutical composition including edaravone with a time interval from a consumption of a meal by the subject in need thereof to an administration of the pharmaceutical composition to the subject in need thereof. The time interval is 8 hours or longer after the consumption of a high-fat meal, the time interval is 4 hours or longer after the consumption of a standard meal, or the time interval is 2 hours or longer after the consumption of a light meal.
    Type: Grant
    Filed: December 29, 2021
    Date of Patent: February 27, 2024
    Assignee: MITSUBISHI TANABE PHARMA CORPORATION
    Inventors: Hidetoshi Shimizu, Yoshinobu Nakamaru, Yukiko Nishimura
  • Publication number: 20230270722
    Abstract: A method of treating an oxidative stress disease includes orally or intragastrically administering, to a subject in need thereof, a pharmaceutical composition including edaravone with a time interval from a consumption of a meal by the subject in need thereof to an administration of the pharmaceutical composition to the subject in need thereof. The time interval is 8 hours or longer after the consumption of a high-fat meal, the time interval is 4 hours or longer after the consumption of a standard meal, or the time interval is 2 hours or longer after the consumption of a light meal.
    Type: Application
    Filed: May 3, 2023
    Publication date: August 31, 2023
    Applicant: MITSUBISHI TANABE PHARMA CORPORATION
    Inventors: Hidetoshi SHIMIZU, Yoshinobu NAKAMARU, Yukiko NISHIMURA
  • Publication number: 20220142982
    Abstract: A method of treating an oxidative stress disease includes orally or intragastrically administering, to a subject in need thereof, a pharmaceutical composition including edaravone with a time interval from a consumption of a meal by the subject in need thereof to an administration of the pharmaceutical composition to the subject in need thereof. The time interval is 8 hours or longer after the consumption of a high-fat meal, the time interval is 4 hours or longer after the consumption of a standard meal, or the time interval is 2 hours or longer after the consumption of a light meal.
    Type: Application
    Filed: December 29, 2021
    Publication date: May 12, 2022
    Applicant: MITSUBISHI TANABE PHARMA CORPORATION
    Inventors: Hidetoshi SHIMIZU, Yoshinobu NAKAMARU, Yukiko NISHIMURA
  • Patent number: 6854124
    Abstract: The disk drive unit of the present invention comprises: a main body; a tray including a disk accommodating section in which an optical disk is held, the tray being retracted into and ejected from the main body; and a driving mechanism for driving the tray. The driving mechanism automatically retracts the tray into and ejects the tray from the main body. The driving mechanism moves the tray when the tray is pushed toward inside of the main body. With this structure, no button for ejecting and retracting the tray is required, and the tray can be ejected and retracted by the same action.
    Type: Grant
    Filed: June 10, 2002
    Date of Patent: February 8, 2005
    Assignee: Shinano Kenshi Kabushiki Kaisha
    Inventors: Hidetoshi Shimizu, Shinya Takizawa
  • Publication number: 20020186640
    Abstract: The disk drive unit of the present invention comprises: a main body; a tray including a disk accommodating section in which an optical disk is held, the tray being retracted into and ejected from the main body; and a driving mechanism for driving the tray. The driving mechanism automatically retracts the tray into and ejects the tray from the main body. The driving mechanism moves the tray when the tray is pushed toward inside of the main body. With this structure, no button for ejecting and retracting the tray is required, and the tray can be ejected and retracted by the same action.
    Type: Application
    Filed: June 10, 2002
    Publication date: December 12, 2002
    Inventors: Hidetoshi Shimizu, Shinya Takizawa
  • Patent number: 5706915
    Abstract: A brake disc rotor includes: a pair of disc-shaped sliding plates provided in parallel with and separately from each other in the axle direction; a plurality of partition walls radially provided between the sliding plates; a plurality of passages radially formed between the plurality of partition walls; a plurality of inlet and outlet openings communicating with the plurality of passages and opening inward and in the radially outward direction; and an inclined portion formed on the surface of the inside sliding plate opposed to the outside sliding plate such that a distance between the inside and outside sliding plates is gradually decreased in the radially outward direction.
    Type: Grant
    Filed: September 18, 1996
    Date of Patent: January 13, 1998
    Assignees: Kabushiki Kaisha Toyota Chuo Kenkyusho, Toyota Jidosha Kabushiki Kaisha
    Inventors: Takashi Shimazu, Haruo Katagiri, Shigeru Sakamoto, Hidetoshi Shimizu
  • Patent number: 5526905
    Abstract: A brake disc rotor which includes sliding plates on the inside and outside which are in parallel with and separated from each other in the axial direction of an axle; a plurality of inner and outer partition walls radially arranged between the sliding plates; a plurality of passages radially formed between the inner and outer partition walls; a plurality of inlet and outlet openings for communicating the passages; and a plurality of connecting openings for communicating the mutually adjacent passages. The stream flowing from the inlet opening is formed along an upper wall of the inner partition walls and the stream is formed in a flow separation portion in the vicinity of a lower wall of the outer partition wall through the connecting openings.
    Type: Grant
    Filed: March 9, 1995
    Date of Patent: June 18, 1996
    Assignees: Kabushiki Kaisha Toyota Chuo Kenkyusho, Toyota Jidosha Kabushiki Kaisha, Aisin Takaoka Co., Ltd.
    Inventors: Takashi Shimazu, Haruo Katagiri, Shigeru Sakamoto, Hidetoshi Shimizu, Akio Inatomi, Masashi Ishihara, Masayoshi Katagiri, Toru Shinoda
  • Patent number: 5467846
    Abstract: In a disc brake assembly including a caliper member mounted on a vehicle body structure in such a manner as to straddle a portion of a rotary brake disc secured for a road wheel, a friction pad supported on the caliper member by means of a pair of hanger pins to be moved toward and away from one side surface of the brake disc for engagement therewith and disengagement therefrom, the friction pad having a backing plate secured thereto to be engaged at one side end face thereof with a torque receiving portion of the caliper member in braking operation and a fluid actuator mounted within the caliper member to press the friction pad against the one side surface of the brake disc, a side projection is provided on at least an upper or lower portion of the one side end face of the backing plate for engagement with the torque receiving portion of the caliper member or on at least an upper or lower portion of the torque receiving portion of the caliper member for engagement with the one side face of said backing plate
    Type: Grant
    Filed: May 12, 1994
    Date of Patent: November 21, 1995
    Assignee: Toyota Jidosha Kabushiki Kaisha
    Inventors: Kazuo Abe, Masashi Ishihara, Hitoshi Ikeuchi, Shinsuke Sugano, Toshiharu Okuda, Shigemi Sakakibara, Hidetoshi Shimizu, Yasuaki Ichiba
  • Patent number: 5427212
    Abstract: A brake disc rotor comprising: sliding plates on the inside and outside in parallel with and separated from each other in the axial direction of an axle; fins composed of a plurality of curved long partition walls provided between the sliding plates, radially extending from the internal portion to the external portion, and inclined with respect to the radial direction, and a plurality of curved short partition walls provided in parallel between the mutually adjacent long partition walls and extending from a large-diameter internal portion to the external portion; a plurality of ventilation holes radially divided by the fins and composed of the upper and lower ventilation holes with the short partition walls; and inlet and outlet openings opened inward and outward in the radial direction thereof.
    Type: Grant
    Filed: September 26, 1994
    Date of Patent: June 27, 1995
    Assignees: Kabushiki Kaisha Toyota Chuo Kenkyusho, Toyota Jidosha Kabushiki Kaisha, Aisin Takaoka Co., Ltd.
    Inventors: Takashi Shimazu, Haruo Katagiri, Shigeru Sakamoto, Hidetoshi Shimizu, Akio Inatomi, Masashi Ishihara, Toru Shinoda
  • Patent number: 5420842
    Abstract: The object of the present invention is to provide a disk player, which is capable of changing the playing linear velocity by multiple stages to shorten the reading time. The disk player comprises includes an optical pick-up for reading data and outputting data signals; a first clock section for generating master clock signals, the first clock section being capable of changing the frequency of the master clock signals by multiple stages; a second clock section for generating second clock signals; a comparing section for comparing frequency and phase of the master clock signals and the second signals and generating deviation signals; and a drive section for sending drive signals, whose voltage level changes according to voltage changes of the deviation signals, to a motor for rotating a disk, whereby the drive section controls the motor so as to synchronize the frequency and the phase of the second clock signals with those of the master clock signals.
    Type: Grant
    Filed: October 21, 1993
    Date of Patent: May 30, 1995
    Assignee: Shinano Kenshi Kabushiki Kaisha
    Inventor: Hidetoshi Shimizu
  • Patent number: 5414685
    Abstract: An object of the invention is to provide a disk player, which is capable of accessing to a disk in a short time, having higher durability and lower electric power consumption. The disk player comprising: a motor for rotating a disk; an optical pick-up for reading recorded data, which include synchronizing signals and output-data elements, and outputting as first signals; a first clock section for extracting the synchronizing signals and generating first clock signals, whose frequency is equal to that of the synchronizing signals; a second clock section for generating second clock signals and coinciding the frequency and the phase of the second clock signals with that of the first clock signals; a data extracting section for extracting the output-data elements on the basis of the second clock signals and outputting as second signals; and a processing section for rotating the motor at fixed rotational speed.
    Type: Grant
    Filed: October 4, 1993
    Date of Patent: May 9, 1995
    Assignee: Shinano Kenshi Kabushiki Kaisha
    Inventor: Hidetoshi Shimizu
  • Patent number: 5379868
    Abstract: A braking device for an automotive vehicle having a master cylinder to be operated by depression of a brake pedal for producing master cylinder pressure and a wheel brake assembly movably mounted to a road wheel to be operated by the master cylinder pressure applied thereto for applying a braking force to the road wheel in accordance with the depression force of the brake pedal. The braking device includes a hydraulic servo unit mounted on an axle housing of the road wheel and operatively connected to the wheel brake assembly for generating a servo-pressure in a predetermined relationship with the braking force in response to movement of the wheel brake assembly and a hydraulic control device arranged to apply the servo-pressure to the wheel brake assembly when the servo-pressure does not increase in a predetermined relationship with a increase of the master cylinder pressure.
    Type: Grant
    Filed: April 16, 1993
    Date of Patent: January 10, 1995
    Assignee: Toyota Jidosha Kabushiki Kaisha
    Inventors: Ryoichi Kurasako, Hidetoshi Shimizu
  • Patent number: 5055968
    Abstract: A method for producing an information card by printing an electroconductive pattern and a first electrode surface of a battery on a first cover sheet, applying a battery activator onto the first electrode surface, resting an electrolyte-impregnated separator onto the first electrode surface, fixing an IC chip to the electroconductive pattern in a predetermined position, printing a second electrode surface of the battery on a second cover sheet, applying a battery activator onto the second electrode surface, and lapping and sticking the first and second cover sheets together and cutting them into a predetermined size.
    Type: Grant
    Filed: July 3, 1989
    Date of Patent: October 8, 1991
    Assignee: Sony Corporation
    Inventors: Yoshio Nishi, Akio Yasuda, Tsunehiro Kashima, Takeshi Hori, Shigetaka Higuchi, Hidetoshi Shimizu
  • Patent number: 4842968
    Abstract: There is disclosed herein a hologram recording medium comprising of substrate formed of transparent and non-light scattering material having a plurality of open pores for said substrate and photopolymerization composition impregnated in said open pores. The photopolymerization composition consists essentially of a photopolymerizable monomer or oligomer which adheres to the surface of said open pores, a photopolymerization initiator and activator for controlling the photopolymerization speed.
    Type: Grant
    Filed: December 16, 1985
    Date of Patent: June 27, 1989
    Assignee: Sony Corporation
    Inventors: Chiaki Kojima, Hidetoshi Shimizu
  • Patent number: 4819163
    Abstract: A driving power control system for a vehicle which minimizes the shock due to a gear change by keeping a driving force constant throughout the shifting, resulting in high drivability. The system includes a mechanism for controlling the engine power to keep driving force unchanged, mechanisms for respectively keeping the acceleration and driving force constant throughout the shifting, and a second throttle valve for controlling the engine power.
    Type: Grant
    Filed: December 1, 1986
    Date of Patent: April 4, 1989
    Assignee: Toyota Jidosha Kabushiki Kaisha
    Inventors: Hidetoshi Shimizu, Shigeru Terada, Yasuhiko Mishio
  • Patent number: 4771842
    Abstract: A vehicle has an engine and a driven differential. This three part type propeller shaft assembly includes a first propeller shaft element, a second propeller shaft element, and a third propeller shaft element. A first joint, which is a Hooke joint, rotationally couples the to a one end of the first propeller shaft element. A second joint rotationally couples the other end of the first propeller shaft element to a one end of the second propeller shaft element. A third joint rotationally couples the other end of the second propeller shaft element to a one end of the third propeller shaft element. And a fourth joint, which is a Hooke joint, rotationally couples the other end of the third propeller shaft element to the driven differential. Two bearing supports, one disposed near each end of the second propeller shaft element, rotatably support it from the vehicle body. One of the second joint and the third joint is a Hooke joint, and the other is a constant velocity type joint.
    Type: Grant
    Filed: January 11, 1988
    Date of Patent: September 20, 1988
    Assignee: Toyota Jidosha Kabushiki Kaisha
    Inventors: Yasuhiko Mishio, Hidetoshi Shimizu, Takashi Matsuda, Masaru Takeda
  • Patent number: 4766969
    Abstract: A vehicle has an engine and a driven differential. This three part type propeller shaft assembly includes a first propeller shaft element, a second propeller shaft element, and a third propeller shaft element. A first joint incorporating a Hooke joint rotationally couples the engine to a one end of the first propeller shaft element. A second joint incorporating a Hooke joint rotationally couples the other end of the first propeller shaft element to a one end of the second propeller shaft element. A third joint incorporating a Hooke joint rotationally couples the other end of the second propeller shaft element to a one end of the third propeller shaft element. And a fourth joint incorporating a Hooke joint rotationally couples the other end of the third propeller shaft element to the driven differential. Two bearing supports, one disposed near each end of the second propeller shaft element, elastically and rotatably support it from the vehicle body.
    Type: Grant
    Filed: January 21, 1987
    Date of Patent: August 30, 1988
    Assignee: Toyota Jidosha Kabushiki Kaisha
    Inventors: Yasuhiko Mishio, Hidetoshi Shimizu, Takashi Matsuda, Masaru Takeda
  • Patent number: 4471437
    Abstract: An overdrive control apparatus is provided with a gradient sensor unit for sensing a gradient of a vehicle running road. The overdrive control apparatus releases an overdrive mode of an automatic change gear device which is set up for a level drive of the vehicle in accordance with a sensing signal from the gradient sensing unit.
    Type: Grant
    Filed: April 1, 1981
    Date of Patent: September 11, 1984
    Assignees: Nippon Soken, Inc., Toyota Jidosha Kogyo Kabushiki Kaisha
    Inventors: Yasuhisa Yoshino, Akira Kuno, Hidetoshi Shimizu, Harumasa Minegishi
  • Patent number: 4434202
    Abstract: The slide member is composed of a polymer composite material containing an unsaturated polyester resin, a thermoplastic resin and a granular inorganic filler. The slide member is of a double construction the surface of which is removed so as to expose part of the surface of the inorganic filler.The slide member thus constructed has particularly a favorable tape travelling property because it has a low friction coefficient, as well as the favorable properties inherent in the polymer composite material.
    Type: Grant
    Filed: November 20, 1981
    Date of Patent: February 28, 1984
    Assignee: Sony Corporation
    Inventors: Satoru Uedaira, Hidetoshi Shimizu, Hidemasa Tamura, Hiromichi Taguchi, Hiroshi Yamanoi, Yoshimi Makino
  • Patent number: 4337651
    Abstract: An apparatus measures and indicates the speeds of a vehicle at the beginning and end of braking of the vehicle by counting as many vehicle speed representative pulse signals as indicative of the speed per hour of the vehicle which are gated during the time that the desired number of clock pulses are counted in response to the beginning and end of braking of the vehicle, respectively.
    Type: Grant
    Filed: November 24, 1980
    Date of Patent: July 6, 1982
    Assignees: Nippon Soken, Inc., Toyota Jidosha Kogyo Kabushiki Kaisha
    Inventors: Yasuhisa Yoshino, Akira Kuno, Hidetoshi Shimizu, Harumasa Minegishi