Patents by Inventor Hidetoshi Shimizu
Hidetoshi Shimizu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250057812Abstract: A method of treating an oxidative stress disease includes orally or intragastrically administering, to a subject in need thereof, a pharmaceutical composition including edaravone with a time interval from a consumption of a meal by the subject in need thereof to an administration of the pharmaceutical composition to the subject in need thereof. The time interval is 8 hours or longer after the consumption of a high-fat meal, the time interval is 4 hours or longer after the consumption of a standard meal, or the time interval is 2 hours or longer after the consumption of a light meal.Type: ApplicationFiled: October 31, 2024Publication date: February 20, 2025Applicant: MITSUBISHI TANABE PHARMA CORPORATIONInventors: Hidetoshi SHIMIZU, Yoshinobu NAKAMARU, Yukiko NISHIMURA
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Publication number: 20250049760Abstract: A method of treating an oxidative stress disease includes orally or intragastrically administering, to a subject in need thereof, a pharmaceutical composition including edaravone with a time interval from a consumption of a meal by the subject in need thereof to an administration of the pharmaceutical composition to the subject in need thereof. The time interval is 8 hours or longer after the consumption of a high-fat meal, the time interval is 4 hours or longer after the consumption of a standard meal, or the time interval is 2 hours or longer after the consumption of a light meal.Type: ApplicationFiled: October 31, 2024Publication date: February 13, 2025Applicant: MITSUBISHI TANABE PHARMA CORPORATIONInventors: Hidetoshi SHIMIZU, Yoshinobu NAKAMARU, Yukiko NISHIMURA
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Publication number: 20250040283Abstract: Provided is a light detection device which allows influence on adjacent pixels to be reduced. The light detection device includes a first substrate portion, a second substrate portion, and a through via. The first substrate portion has a pixel configured to photoelectrically convert incident light. The second substrate portion has a readout circuit configured to output a pixel signal based on charge output from the pixel to a signal line. The through via configured to connect the first substrate portion and the second substrate portion. The pixel has a floating diffusion configured to temporarily retain charge generated by photoelectric conversion. The readout circuit has a first pixel transistor connected to the floating diffusion through the through via and a second pixel transistor connected to the first pixel transistor and the signal line.Type: ApplicationFiled: December 1, 2022Publication date: January 30, 2025Inventors: MACHIKO KAMETANI, MANABU TOMITA, HIROFUMI YAMASHITA, KEIJI NISHIDA, RYOHEI TAKAYANAGI, SHINICHI MIYAKE, HIDETOSHI OISHI, AKITO SHIMIZU, TAKANORI OKAMURA
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Patent number: 12194025Abstract: A method of treating an oxidative stress disease includes orally or intragastrically administering, to a subject in need thereof, a pharmaceutical composition including edaravone with a time interval from a consumption of a meal by the subject in need thereof to an administration of the pharmaceutical composition to the subject in need thereof. The time interval is 8 hours or longer after the consumption of a high-fat meal, the time interval is 4 hours or longer after the consumption of a standard meal, or the time interval is 2 hours or longer after the consumption of a light meal.Type: GrantFiled: May 3, 2023Date of Patent: January 14, 2025Assignee: MITSUBISHI TANABE PHARMA CORPORATIONInventors: Hidetoshi Shimizu, Yoshinobu Nakamaru, Yukiko Nishimura
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Publication number: 20240173297Abstract: A method of treating an oxidative stress disease includes orally or intragastrically administering, to a subject in need thereof, a pharmaceutical composition including edaravone with a time interval from a consumption of a meal by the subject in need thereof to an administration of the pharmaceutical composition to the subject in need thereof. The time interval is 8 hours or longer after the consumption of a high-fat meal, the time interval is 4 hours or longer after the consumption of a standard meal, or the time interval is 2 hours or longer after the consumption of a light meal.Type: ApplicationFiled: December 28, 2023Publication date: May 30, 2024Applicant: MITSUBISHI TANABE PHARMA CORPORATIONInventors: Hidetoshi SHIMIZU, Yoshinobu NAKAMARU, Yukiko NISHIMURA
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Patent number: 11911366Abstract: A method of treating an oxidative stress disease includes orally or intragastrically administering, to a subject in need thereof, a pharmaceutical composition including edaravone with a time interval from a consumption of a meal by the subject in need thereof to an administration of the pharmaceutical composition to the subject in need thereof. The time interval is 8 hours or longer after the consumption of a high-fat meal, the time interval is 4 hours or longer after the consumption of a standard meal, or the time interval is 2 hours or longer after the consumption of a light meal.Type: GrantFiled: December 29, 2021Date of Patent: February 27, 2024Assignee: MITSUBISHI TANABE PHARMA CORPORATIONInventors: Hidetoshi Shimizu, Yoshinobu Nakamaru, Yukiko Nishimura
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Publication number: 20230270722Abstract: A method of treating an oxidative stress disease includes orally or intragastrically administering, to a subject in need thereof, a pharmaceutical composition including edaravone with a time interval from a consumption of a meal by the subject in need thereof to an administration of the pharmaceutical composition to the subject in need thereof. The time interval is 8 hours or longer after the consumption of a high-fat meal, the time interval is 4 hours or longer after the consumption of a standard meal, or the time interval is 2 hours or longer after the consumption of a light meal.Type: ApplicationFiled: May 3, 2023Publication date: August 31, 2023Applicant: MITSUBISHI TANABE PHARMA CORPORATIONInventors: Hidetoshi SHIMIZU, Yoshinobu NAKAMARU, Yukiko NISHIMURA
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Publication number: 20220142982Abstract: A method of treating an oxidative stress disease includes orally or intragastrically administering, to a subject in need thereof, a pharmaceutical composition including edaravone with a time interval from a consumption of a meal by the subject in need thereof to an administration of the pharmaceutical composition to the subject in need thereof. The time interval is 8 hours or longer after the consumption of a high-fat meal, the time interval is 4 hours or longer after the consumption of a standard meal, or the time interval is 2 hours or longer after the consumption of a light meal.Type: ApplicationFiled: December 29, 2021Publication date: May 12, 2022Applicant: MITSUBISHI TANABE PHARMA CORPORATIONInventors: Hidetoshi SHIMIZU, Yoshinobu NAKAMARU, Yukiko NISHIMURA
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Patent number: 6854124Abstract: The disk drive unit of the present invention comprises: a main body; a tray including a disk accommodating section in which an optical disk is held, the tray being retracted into and ejected from the main body; and a driving mechanism for driving the tray. The driving mechanism automatically retracts the tray into and ejects the tray from the main body. The driving mechanism moves the tray when the tray is pushed toward inside of the main body. With this structure, no button for ejecting and retracting the tray is required, and the tray can be ejected and retracted by the same action.Type: GrantFiled: June 10, 2002Date of Patent: February 8, 2005Assignee: Shinano Kenshi Kabushiki KaishaInventors: Hidetoshi Shimizu, Shinya Takizawa
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Publication number: 20020186640Abstract: The disk drive unit of the present invention comprises: a main body; a tray including a disk accommodating section in which an optical disk is held, the tray being retracted into and ejected from the main body; and a driving mechanism for driving the tray. The driving mechanism automatically retracts the tray into and ejects the tray from the main body. The driving mechanism moves the tray when the tray is pushed toward inside of the main body. With this structure, no button for ejecting and retracting the tray is required, and the tray can be ejected and retracted by the same action.Type: ApplicationFiled: June 10, 2002Publication date: December 12, 2002Inventors: Hidetoshi Shimizu, Shinya Takizawa
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Patent number: 5706915Abstract: A brake disc rotor includes: a pair of disc-shaped sliding plates provided in parallel with and separately from each other in the axle direction; a plurality of partition walls radially provided between the sliding plates; a plurality of passages radially formed between the plurality of partition walls; a plurality of inlet and outlet openings communicating with the plurality of passages and opening inward and in the radially outward direction; and an inclined portion formed on the surface of the inside sliding plate opposed to the outside sliding plate such that a distance between the inside and outside sliding plates is gradually decreased in the radially outward direction.Type: GrantFiled: September 18, 1996Date of Patent: January 13, 1998Assignees: Kabushiki Kaisha Toyota Chuo Kenkyusho, Toyota Jidosha Kabushiki KaishaInventors: Takashi Shimazu, Haruo Katagiri, Shigeru Sakamoto, Hidetoshi Shimizu
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Patent number: 5526905Abstract: A brake disc rotor which includes sliding plates on the inside and outside which are in parallel with and separated from each other in the axial direction of an axle; a plurality of inner and outer partition walls radially arranged between the sliding plates; a plurality of passages radially formed between the inner and outer partition walls; a plurality of inlet and outlet openings for communicating the passages; and a plurality of connecting openings for communicating the mutually adjacent passages. The stream flowing from the inlet opening is formed along an upper wall of the inner partition walls and the stream is formed in a flow separation portion in the vicinity of a lower wall of the outer partition wall through the connecting openings.Type: GrantFiled: March 9, 1995Date of Patent: June 18, 1996Assignees: Kabushiki Kaisha Toyota Chuo Kenkyusho, Toyota Jidosha Kabushiki Kaisha, Aisin Takaoka Co., Ltd.Inventors: Takashi Shimazu, Haruo Katagiri, Shigeru Sakamoto, Hidetoshi Shimizu, Akio Inatomi, Masashi Ishihara, Masayoshi Katagiri, Toru Shinoda
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Patent number: 5467846Abstract: In a disc brake assembly including a caliper member mounted on a vehicle body structure in such a manner as to straddle a portion of a rotary brake disc secured for a road wheel, a friction pad supported on the caliper member by means of a pair of hanger pins to be moved toward and away from one side surface of the brake disc for engagement therewith and disengagement therefrom, the friction pad having a backing plate secured thereto to be engaged at one side end face thereof with a torque receiving portion of the caliper member in braking operation and a fluid actuator mounted within the caliper member to press the friction pad against the one side surface of the brake disc, a side projection is provided on at least an upper or lower portion of the one side end face of the backing plate for engagement with the torque receiving portion of the caliper member or on at least an upper or lower portion of the torque receiving portion of the caliper member for engagement with the one side face of said backing plateType: GrantFiled: May 12, 1994Date of Patent: November 21, 1995Assignee: Toyota Jidosha Kabushiki KaishaInventors: Kazuo Abe, Masashi Ishihara, Hitoshi Ikeuchi, Shinsuke Sugano, Toshiharu Okuda, Shigemi Sakakibara, Hidetoshi Shimizu, Yasuaki Ichiba
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Patent number: 5427212Abstract: A brake disc rotor comprising: sliding plates on the inside and outside in parallel with and separated from each other in the axial direction of an axle; fins composed of a plurality of curved long partition walls provided between the sliding plates, radially extending from the internal portion to the external portion, and inclined with respect to the radial direction, and a plurality of curved short partition walls provided in parallel between the mutually adjacent long partition walls and extending from a large-diameter internal portion to the external portion; a plurality of ventilation holes radially divided by the fins and composed of the upper and lower ventilation holes with the short partition walls; and inlet and outlet openings opened inward and outward in the radial direction thereof.Type: GrantFiled: September 26, 1994Date of Patent: June 27, 1995Assignees: Kabushiki Kaisha Toyota Chuo Kenkyusho, Toyota Jidosha Kabushiki Kaisha, Aisin Takaoka Co., Ltd.Inventors: Takashi Shimazu, Haruo Katagiri, Shigeru Sakamoto, Hidetoshi Shimizu, Akio Inatomi, Masashi Ishihara, Toru Shinoda
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Patent number: 5420842Abstract: The object of the present invention is to provide a disk player, which is capable of changing the playing linear velocity by multiple stages to shorten the reading time. The disk player comprises includes an optical pick-up for reading data and outputting data signals; a first clock section for generating master clock signals, the first clock section being capable of changing the frequency of the master clock signals by multiple stages; a second clock section for generating second clock signals; a comparing section for comparing frequency and phase of the master clock signals and the second signals and generating deviation signals; and a drive section for sending drive signals, whose voltage level changes according to voltage changes of the deviation signals, to a motor for rotating a disk, whereby the drive section controls the motor so as to synchronize the frequency and the phase of the second clock signals with those of the master clock signals.Type: GrantFiled: October 21, 1993Date of Patent: May 30, 1995Assignee: Shinano Kenshi Kabushiki KaishaInventor: Hidetoshi Shimizu
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Patent number: 5414685Abstract: An object of the invention is to provide a disk player, which is capable of accessing to a disk in a short time, having higher durability and lower electric power consumption. The disk player comprising: a motor for rotating a disk; an optical pick-up for reading recorded data, which include synchronizing signals and output-data elements, and outputting as first signals; a first clock section for extracting the synchronizing signals and generating first clock signals, whose frequency is equal to that of the synchronizing signals; a second clock section for generating second clock signals and coinciding the frequency and the phase of the second clock signals with that of the first clock signals; a data extracting section for extracting the output-data elements on the basis of the second clock signals and outputting as second signals; and a processing section for rotating the motor at fixed rotational speed.Type: GrantFiled: October 4, 1993Date of Patent: May 9, 1995Assignee: Shinano Kenshi Kabushiki KaishaInventor: Hidetoshi Shimizu
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Patent number: 5379868Abstract: A braking device for an automotive vehicle having a master cylinder to be operated by depression of a brake pedal for producing master cylinder pressure and a wheel brake assembly movably mounted to a road wheel to be operated by the master cylinder pressure applied thereto for applying a braking force to the road wheel in accordance with the depression force of the brake pedal. The braking device includes a hydraulic servo unit mounted on an axle housing of the road wheel and operatively connected to the wheel brake assembly for generating a servo-pressure in a predetermined relationship with the braking force in response to movement of the wheel brake assembly and a hydraulic control device arranged to apply the servo-pressure to the wheel brake assembly when the servo-pressure does not increase in a predetermined relationship with a increase of the master cylinder pressure.Type: GrantFiled: April 16, 1993Date of Patent: January 10, 1995Assignee: Toyota Jidosha Kabushiki KaishaInventors: Ryoichi Kurasako, Hidetoshi Shimizu
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Patent number: 5055968Abstract: A method for producing an information card by printing an electroconductive pattern and a first electrode surface of a battery on a first cover sheet, applying a battery activator onto the first electrode surface, resting an electrolyte-impregnated separator onto the first electrode surface, fixing an IC chip to the electroconductive pattern in a predetermined position, printing a second electrode surface of the battery on a second cover sheet, applying a battery activator onto the second electrode surface, and lapping and sticking the first and second cover sheets together and cutting them into a predetermined size.Type: GrantFiled: July 3, 1989Date of Patent: October 8, 1991Assignee: Sony CorporationInventors: Yoshio Nishi, Akio Yasuda, Tsunehiro Kashima, Takeshi Hori, Shigetaka Higuchi, Hidetoshi Shimizu
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Patent number: 4842968Abstract: There is disclosed herein a hologram recording medium comprising of substrate formed of transparent and non-light scattering material having a plurality of open pores for said substrate and photopolymerization composition impregnated in said open pores. The photopolymerization composition consists essentially of a photopolymerizable monomer or oligomer which adheres to the surface of said open pores, a photopolymerization initiator and activator for controlling the photopolymerization speed.Type: GrantFiled: December 16, 1985Date of Patent: June 27, 1989Assignee: Sony CorporationInventors: Chiaki Kojima, Hidetoshi Shimizu
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Patent number: 4819163Abstract: A driving power control system for a vehicle which minimizes the shock due to a gear change by keeping a driving force constant throughout the shifting, resulting in high drivability. The system includes a mechanism for controlling the engine power to keep driving force unchanged, mechanisms for respectively keeping the acceleration and driving force constant throughout the shifting, and a second throttle valve for controlling the engine power.Type: GrantFiled: December 1, 1986Date of Patent: April 4, 1989Assignee: Toyota Jidosha Kabushiki KaishaInventors: Hidetoshi Shimizu, Shigeru Terada, Yasuhiko Mishio