Patents by Inventor Hidetsune Tamaoki

Hidetsune Tamaoki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • External formulation containing loxoprofen
    Patent number: 6248350
    Abstract: An anti-inflammatory analgesic patch containing loxoprofen, crotamiton, solvent, skin permeation accelerator, water-soluble polymers and moisturizers. The patch allows for the loxoprofen to penetrate the skin.
    Type: Grant
    Filed: February 19, 1999
    Date of Patent: June 19, 2001
    Assignee: Lead Chemical Co., Ltd.
    Inventors: Masao Mori, Hidetsune Tamaoki, Tamaki Horiuchi
  • Enkephalinase B inhibitors, their preparation, and pharmaceutical compositions containing the same
    Patent number: 4804676
    Abstract: Propioxatins A and B, which have the formula: ##STR1## wherein R represents a hydrogen atom or a methyl group, can be prepared by cultivating a suitable strain of Kitasatosporia, e.g. Kitasatosporia sp. SANK 60684 (FERM-P 7581). They can be salified to give pharmaceutically acceptable salts. The compounds are active as enkephalinase B inhibitors and are thus capable of enhancing enkephalin activity in vivo.
    Type: Grant
    Filed: October 1, 1985
    Date of Patent: February 14, 1989
    Assignee: Sankyo Company Limited
    Inventors: Yoshinori Inaoka, Shuji Takahashi, Hidetsune Tamaoki, Ryuzo Enokita
  • Preparation of peptides with C-terminal proline amide
    Patent number: 4709014
    Abstract: A peptide with C-terminal proline amide is produced by reacting in aqueous solution a protein substrate having C-terminal prolyl-leucine, prolyl-isoleucine, prolyl-valine, or prolyl-phenylalanine with carboxypeptidase Y in the presence of ammonia. The ammonia is preferably generated by the aqueous reaction of an ammonium salt and an alkali. An example of the peptide product is human calcitonin.
    Type: Grant
    Filed: April 1, 1986
    Date of Patent: November 24, 1987
    Assignee: Sankyo Company Limited
    Inventor: Hidetsune Tamaoki