Patents by Inventor Hideyuki Okuyama

Hideyuki Okuyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240101532
    Abstract: A compound useful as an active ingredient of a pharmaceutical composition for treatment of cancer related to activation of immune cells or cancer resistant to anti-PD-1 antibody/anti-PD-L1 antibody therapy is provided. The present inventors have conducted studies on a compound useful as an active ingredient of a pharmaceutical composition for treatment of cancer related to activation of immune cells or cancer resistant to anti-PD-1 antibody/anti-PD-L1 antibody therapy, and confirmed that a heteroaryl carboxamide compound has DGK ? (DGKzeta) inhibitory effect, leading to completion of the present invention. The heteroaryl carboxamide compound of the present invention has DGK ? inhibitory effect, and can be used as a therapeutic agent for treatment of cancer related to activation of immune cells or cancer resistant to anti-PD-1 antibody/anti-PD-L1 antibody therapy.
    Type: Application
    Filed: November 28, 2023
    Publication date: March 28, 2024
    Inventors: Hideyuki Watanabe, Takashi Kamikubo, Akio Kamikawa, Takuya Washio, Yohei Seki, Keiichiro Okuyama, Osamu Ikeda, Hiroshi Tomiyama, Yoshinori Iwai, Akihiko Nakamura, Kozo Miyasaka
  • Patent number: 8986182
    Abstract: The paper feed roller according to the present invention is made of a thermoplastic elastomer composition containing an ester thermoplastic elastomer urethane or an ether thermoplastic elastomer urethane (E) having microrubber hardness (type A) of not less than 60 and not more than 80 and a plasticizer (P) in a mass ratio E/P of 70/30 to 50/50.
    Type: Grant
    Filed: July 22, 2010
    Date of Patent: March 24, 2015
    Assignee: Sumitomo Rubber Industries, Ltd.
    Inventors: Toshihiro Tamura, Akihiro Mine, Hirokazu Nishimori, Hideyuki Okuyama
  • Patent number: 8420738
    Abstract: A thermoplastic elastomer composition which has excellent cleanability and is suitable for use as a medical rubber supply. It is characterized by comprising a rubber ingredient dynamically crosslinked with a crosslinking agent and a matrix which comprises a thermoplastic resin and in which the crosslinked rubber ingredient has been dispersed, the crosslinking agent comprising a triazine derivative.
    Type: Grant
    Filed: October 2, 2008
    Date of Patent: April 16, 2013
    Assignee: Sumitomo Rubber Industries, Ltd.
    Inventors: Hiroaki Nakano, Hideyuki Okuyama
  • Patent number: 8147939
    Abstract: The present invention provides an artificial grass granulated infill excellent in productivity, workability, and recyclability, and an artificial grass structure using the same. A hollow cylindrical granulated infill 5 which has a height h of 3.0 mm or less and an outside diameter of 3.0 mm or less and satisfies the condition: ?2/?1=0.40 to 0.85, where ?1 presents the outside diameter and ?2 represents the inside diameter, is made from a material comprising a synthetic resin having a hardness of 60 or more in accordance with JIS-K6253 type A.
    Type: Grant
    Filed: April 14, 2009
    Date of Patent: April 3, 2012
    Assignee: Sumitomo Rubber Industries Ltd.
    Inventors: Takashi Horio, Hideyuki Okuyama, Takeshi Ishmaru, Yoshimichi Tanaka
  • Patent number: 8023869
    Abstract: The present invention provides a conductive roller whose outermost layer is made of a vulcanized rubber composition. The vulcanized rubber composition contains epichlorohydrin rubber and chloroprene rubber as a rubber component thereof and 0.2 to 5 parts by mass of each of a thiourea-based vulcanizing agent and a vulcanization retarder consisting of N-(cyclohexylthio)phthalimide for 100 parts by mass of the rubber component.
    Type: Grant
    Filed: October 16, 2009
    Date of Patent: September 20, 2011
    Assignee: Sumitomo Rubber Industries, Ltd.
    Inventors: Yoshihisa Mizumoto, Masakazu Tanaka, Takashi Marui, Hideyuki Okuyama, Noriaki Hitomi
  • Publication number: 20110189408
    Abstract: A recycling technique for long-pile artificial turfs is provided in which a spent artificial turf is recycled and formed into an elastic particulate substance suitable for use as a filler for long-pile artificial turfs. The particulate substance (5), with which the space among the piles (4) of an artificial turf (3) is filled, is obtained by using as a raw material an artificial turf comprising at least 50 wt. % thermoplastic resin, adding an elastomer to the raw material, and forming the resultant mixture into particles. The particulate substance (5) has a specific gravity regulated to 1.10 or higher and is used for the filling.
    Type: Application
    Filed: November 28, 2008
    Publication date: August 4, 2011
    Inventors: Takeshi Ishimaru, Hideyuki Okuyama
  • Publication number: 20110142503
    Abstract: The conductive roller according to the present invention includes a roller body made of a thermoplastic elastomer composition supplied with conductivity having an outer cylinder constituting an outer peripheral surface of the roller body, an inner cylinder, having an outer diameter smaller than the inner diameter of the outer cylinder, concentrically arranged in the outer cylinder, and a plurality of platelike coupling portions reaching the inner periphery of the outer cylinder from the outer periphery of the inner cylinder, wherein a plurality hollow portions separated from one another by the coupling portions are provided between the outer periphery of the inner cylinder and the inner periphery of the outer cylinder, and each coupling portion is arranged to intersect with a plane passing through the central axes of the outer cylinder and the inner cylinder so that adjacent hollow portions separated from each other by the coupling portion overlap with each other on the plane inwardly and outwardly in the rad
    Type: Application
    Filed: October 19, 2010
    Publication date: June 16, 2011
    Inventors: Yusuke Tanio, Hideyuki Okuyama
  • Publication number: 20110034308
    Abstract: The paper feed roller according to the present invention is made of a thermoplastic elastomer composition containing an ester thermoplastic elastomer urethane or an ether thermoplastic elastomer urethane (E) having microrubber hardness (type A) of not less than 60 and not more than 80 and a plasticizer (P) in a mass ratio E/P of 70/30 to 50/50.
    Type: Application
    Filed: July 22, 2010
    Publication date: February 10, 2011
    Inventors: Toshihiro TAMURA, Akihiro Mine, Hirokazu Nishimori, Hideyuki Okuyama
  • Publication number: 20110034598
    Abstract: The paper feed roller according to the present invention is made of (1) a thermoplastic elastomer composition containing an ester thermoplastic elastomer urethane (E) having microrubber hardness (type A) of not less than 80 and not more than 95 and at least one plasticizer (P) selected from a group consisting of an ether ester plasticizer and a phthalic ester plasticizer in a mass ratio E/P of 95/5 to 70/30, or (2) a thermoplastic elastomer composition containing an ether thermoplastic elastomer urethane (E) having microrubber hardness (type A) of not less than 80 and not more than 95 and at least one plasticizer (P) selected from a group consisting of an ether ester plasticizer, a phthalic ester plasticizer and a phosphoric acid plasticizer in a mass ratio E/P of 95/5 to 70/30.
    Type: Application
    Filed: July 22, 2010
    Publication date: February 10, 2011
    Inventors: Toshihiro TAMURA, Akihiro Mine, Hirokazu Nishimori, Hideyuki Okuyama
  • Publication number: 20100267899
    Abstract: A thermoplastic elastomer composition which has excellent cleanability and is suitable for use as a medical rubber supply. It is characterized by comprising a rubber ingredient dynamically crosslinked with a crosslinking agent and a matrix which comprises a thermoplastic resin and in which the crosslinked rubber ingredient has been dispersed, the crosslinking agent comprising a triazine derivative.
    Type: Application
    Filed: October 2, 2008
    Publication date: October 21, 2010
    Applicant: Sumitomo Rubber Industries, Ltd
    Inventors: Hiroaki Nakano, Hideyuki Okuyama
  • Publication number: 20100261002
    Abstract: A conductive member of a paper feed roller for use in an electrophotographic apparatus is provided which retains electrical conductivity in an adequate range, is effectively prevented from deteriorating in durability, and is reduced in the voltage dependence of electrical resistance and in resistance unevenness. This conductive member enables satisfactory print quality to be obtained over long. The conductive member comprises: a conductive elastic layer formed from one or more elastic materials selected from the group consisting of rubbers, resins, and thermoplastic elastomers; and a coating layer formed by applying a surface-treating liquid to the outer surface of the conductive elastic layer and then thermally curing the coating. The surface-treating liquid comprises: a medium containing, dispersed and/or dissolved therein, either a polyisocyanate compound or a combination of a polyol compound and an isocyanate compound; and carbon nanotubes dispersed in the medium.
    Type: Application
    Filed: October 27, 2008
    Publication date: October 14, 2010
    Applicant: SUMITOMO RUBBER INDUSTRIES, LTD.
    Inventors: Kei Tajima, Hideyuki Okuyama
  • Publication number: 20100227976
    Abstract: Disclosed is a thermoplastic elastomer composition which is excellent in a vibration-proof property and a sound-proof property, and which has flexibility, wear resistance and processability at the levels required for a member (e.g., a roller) to be used in an image-forming device (e.g., a printer). The thermoplastic elastomer composition contains a butyl rubber at a ratio of 30 to 80 mass % (inclusive), and further contains 15 to 50 parts by mass (inclusive) of an olefin thermoplastic resin and 10 to 100 parts by mass (inclusive) of a hydrogenerated styrene thermoplastic elastomer relative to 100 parts by mass of the rubber component, wherein the rubber component is finely dispersed by dynamic cross-linking.
    Type: Application
    Filed: October 9, 2008
    Publication date: September 9, 2010
    Inventors: Hiroaki Nakano, Hideyuki Okuyama
  • Publication number: 20100214376
    Abstract: Disclosed is an ink tube for ink-jet printers, which has excellent flexibility and workability, while being small in compression set as well as in water vapor permeability and air permeability. Specifically, an ink tube for ink-jet printers is made from a thermoplastic elastomer composition which contains a rubber component containing a butyl rubber at a ratio of not less than 30% by mass but not more than 80% by mass, not less than 5 parts by mass but not more than 50% parts by mass of an olefin thermoplastic resin per 100 parts by mass of the rubber component, and not less than 10 parts by mass but not more than 100 parts by mass of a hydrogenated styrene thermoplastic elastomer per 100 parts by mass of the rubber component. In this thermoplastic elastomer composition, the rubber component is finely dispersed by dynamic crosslinking.
    Type: Application
    Filed: October 9, 2008
    Publication date: August 26, 2010
    Inventors: Hiroaki Nakano, Hideyuki Okuyama
  • Publication number: 20100172675
    Abstract: The present invention provides a conductive roller whose outermost layer is made of a vulcanized rubber composition. The vulcanized rubber composition contains epichlorohydrin rubber and chloroprene rubber as a rubber component thereof and 0.2 to 5 parts by mass of each of a thiourea-based vulcanizing agent and a vulcanization retarder consisting of N-(cyclohexylthio)phthalimide for 100 parts by mass of the rubber component.
    Type: Application
    Filed: October 16, 2009
    Publication date: July 8, 2010
    Inventors: Yoshihisa MIZUMOTO, Masakazu Tanaka, Takashi Marui, Hideyuki Okuyama, Noriaki Hitomi
  • Patent number: 7744781
    Abstract: A conductive thermoplastic elastomer composition comprising a component (A) containing a thermoplastic resin or/and a thermoplastic elastomer; a component (B) comprising an ionic-conductive agent containing an ethylene oxide-propylene oxide copolymer or/and an ethylene oxide-propylene oxide-allyl glycidyl ether copolymer and a metal salt contained in the ethylene oxide-propylene oxide copolymer or/and the ethylene oxide-propylene oxide-allyl glycidyl ether copolymer; and a component (C) comprising an ethylene-acrylic ester-maleic anhydride copolymer.
    Type: Grant
    Filed: August 3, 2007
    Date of Patent: June 29, 2010
    Assignee: Sumitomo Rubber Industries, Ltd.
    Inventors: Kei Tajima, Hideyuki Okuyama
  • Publication number: 20090286017
    Abstract: The present invention provides an artificial grass granulated infill excellent in productivity, workability, and recyclability, and an artificial grass structure using the same. A hollow cylindrical granulated infill 5 which has a height h of mm or less and an outside diameter of 3.0 mm or less and satisfies the condition: ?2/?1=0.40 to 0.85, where ?1 presents the outside diameter and ?2 represents the inside diameter, is made from a material comprising a synthetic resin having a hardness of 60 or more in accordance with JIS-K6253 type A.
    Type: Application
    Filed: April 14, 2009
    Publication date: November 19, 2009
    Inventors: Takashi HORIO, Hideyuki OKUYAMA, Takeshi ISHMARU, Yoshimichi TANAKA
  • Publication number: 20090286018
    Abstract: The present invention provides an artificial grass granulated infill excellent in productivity, workability, and recyclability, and an artificial grass structure using the same. The artificial grass granulated infill is made from a material comprising a synthetic resin having a hardness of 60 or more in accordance with type A, and is formed so that the void 51 accounts for 10 to 75% of the total volume (the sum of the volume of the portion in which the material is present and the volume of the void).
    Type: Application
    Filed: April 14, 2009
    Publication date: November 19, 2009
    Inventors: Takashi HORIO, Hideyuki OKUYAMA, Takeshi ISHMARU, Yoshimichi TANAKA
  • Publication number: 20080042108
    Abstract: A conductive thermoplastic elastomer composition comprising a component (A) containing a thermoplastic resin or/and a thermoplastic elastomer; a component (B) comprising an ionic-conductive agent containing an ethylene oxide-propylene oxide copolymer or/and an ethylene oxide-propylene oxide-allyl glycidyl ether copolymer and a metal salt contained in the ethylene oxide-propylene oxide copolymer or/and the ethylene oxide-propylene oxide-allyl glycidyl ether copolymer; and a component (C) comprising an ethylene-acrylic ester-maleic anhydride copolymer.
    Type: Application
    Filed: August 3, 2007
    Publication date: February 21, 2008
    Inventors: Kei Tajima, Hideyuki Okuyama
  • Patent number: 7253233
    Abstract: An elastomer composition is prepared that contains a rubber component (A) containing at least one of diene rubber and EPDM rubber; a mixture composition (B) containing hydrogenated styrene thermoplastic elastomer and olefin resin; and a styrene thermoplastic elastomer (C) having double bonds partly left, wherein the styrene thermoplastic elastomer (C) is blended at a ratio of not less than 2 parts by weight and not more than 100 parts by weight with respect to 200 parts by weight of the mixture composition (B), and the rubber component (A) is dispersed by dynamic crosslinking in the mixture composition (B) having the styrene thermoplastic elastomer (C) dispersed therein. A rubber roller is formed by using the elastomer composition. The elastomer composition is excellent in wear resistance, and the rubber roller made of the elastomer composition is excellent in wear resistance at the time of idling rotation.
    Type: Grant
    Filed: May 6, 2004
    Date of Patent: August 7, 2007
    Assignee: Sumitomo Rubber Industries, Ltd.
    Inventors: Mutsuki Sugimoto, Hideyuki Okuyama
  • Patent number: 7141183
    Abstract: A conductive elastomer composition having rubber-like elasticity and flexibility and thermoplastic-resin-like moldability and realizing a high conductivity. The conductive elastomer composition includes a thermoplastic elastomer composition (A) containing a compound (A1) composed of a thermoplastic resin and/or a thermoplastic elastomer and a compound (A2), composed of a crosslinkable rubber and/or a crosslinkable thermoplastic elastomer, dispersed in the compound (A1) by dynamically crosslinking the compound (A2); and an ionic-conductive agent (B), containing a metal salt and a polyether-containing block copolymer resin, dispersed in the thermoplastic elastomer composition (A). The conductive elastomer composition may contain carbon black (C).
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: November 28, 2006
    Assignee: Sumitomo Rubber Industries, Ltd.
    Inventors: Takayuki Hattori, Tetsuo Mizoguchi, Toshiaki Sakaki, Hideyuki Okuyama