Abstract: The various examples presented herein are directed to compounds of the formula A-L1-Het1-L2-Cy1 or a pharmaceutical acceptable salt, polymorph, prodrug, solvate or clathrate thereof, wherein: A is cycloalkyl, aryl, arylalkyl or heterocyclyl; Het1 is heterocyclyl containing at least two heteroatoms; Cy1 is a heterocyclyl; L1 is a bond, alkyl, alkenyl or alkynyl linker; L2 is an acyl or alkyl linker; and A and Cy1 are different. The compounds are useful in the treatment of fibrotic diseases, abnormal vascular leak and pathological angiogenesis.

Abstract: In a thrust needle roller bearing, even in an environment where an amount of lubricating oil is small, the amount of lubricating oil is held and seizure is prevented. The thrust needle roller bearing includes a plurality of needle rollers, a bearing ring (31) having an annular raceway surface (31a) on which the needle rollers roll, and a cage that rollably holds the needle rollers, in which an oil repellent film (41a) is formed by oil repellent treatment on a portion of the raceway surface (31a) other than a portion in contact with the needle rollers.

Abstract: An optical transmitter includes: an optical modulator of a Mach-Zehnder type using an InP-based material; a bias controller configured to control a DC bias applied to the optical modulator; a monitor configured to monitor output light of the optical modulator to generate a monitor signal; and a corrector configured to correct a gain of the monitor signal in a direction in which wavelength dependency of insertion loss of the optical modulator is compensated according to a wavelength at a preceding stage of bias control by the bias controller.

Abstract: A negative electrode material for a lithium-ion secondary battery comprising graphite particles satisfying x?2.0 when a compressive load required to consolidate to 1.7 g/cm3 in autograph measurement is x (kN/cm2), 5.0?y?20.0 when, a particle size at which a cumulative volume from a small diameter side of a volume-based particle size distribution measured by a laser diffraction method reaches 50% is y, the above mentioned x and y satisfy the following Formula (1), and a degree of graphitization satisfies 90.0% or more: 11.3x?0.66y+1.4?14.5??(1).

Abstract: A pressing operation body includes an inversion spring having a dome shape; and a rubber stem configured to bend in response to pressing and press the inversion spring. The inversion spring includes a dome portion, and a plurality of leg portions that are extended outward from an outer peripheral edge of the dome portion. The rubber stem includes a base portion configured to support a lower edge of the rubber stem. The base portion includes a plurality of retaining portions configured to retain the plurality of leg portions of the inversion spring.

Abstract: An object of the present invention is to provide: an optical element in which incident light can be transmitted or reflected at an angle in the predetermined direction and the wavelength dependence of the amount of transmitted light or reflected light is small; and an optical element including the optical element. The optical element according to the present invention comprises: an optically-anisotropic layer that is formed using a composition including a liquid crystal compound and an infrared absorbing colorant, in which the optically-anisotropic layer has a liquid crystal alignment pattern in which a direction of an optical axis derived from the liquid crystal compound changes while continuously rotating in at least one in-plane direction, and an absorption of the infrared absorbing colorant in a wavelength range of 700 to 2000 nm in a minor axis direction is higher than an absorption of the infrared absorbing colorant in a wavelength range of 700 to 2000 nm in a major axis direction.

Abstract: An overtube for an endoscope includes: a tube body having a main lumen through which the endoscope is inserted and an air-supply lumen through which gas flows; a fixing balloon provided on an outer peripheral surface of a distal end of the tube body, expandable outward from the outer peripheral surface and contractible toward the outer peripheral surface; an air supply device configured to send the gas to the air-supply lumen; and an airtight valve unit having a tubular portion communicating with the main lumen at a rear end of the tube body, the airtight valve unit closing the gap between the endoscope inserted through the tubular portion into the main lumen and an inner peripheral surface of the tubular portion.

Abstract: The present invention provides a method for preparing a somatic chimera by using a pluripotent cell genetically engineered not to differentiate into a predetermined type of cell. The present invention particularly provides a method for preventing a pluripotent cell from contributing to the brain and gonad in a somatic chimera animal.

Abstract: The present invention has found that chimeric animals suffer from noticeable inflammation after birth, though neither immune response nor inflammation in the fetal period of these animals has been reported hitherto. This is an unexpected finding since chimeric animals in the fetal period were exclusively analyzed in prior studies and thus it is deemed that immunotolerance has been theoretically established therein. The present invention provides a composition for suppressing immune response or inflammation in the fetal period of a born chimeric animal.

Abstract: A power amplifier circuit includes a first transistor disposed on a semiconductor substrate; a second transistor that supplies a bias current based on a first current which is a part of a control current to the first transistor; a current output element in which a current flowing therethrough increases in accordance with a rise in temperature; and a wiring portion including a plurality of metal layers that are electrically connected to an emitter of the first transistor and that are stacked one on top of another so as to oppose the semiconductor substrate. At least one metal layer among the plurality of metal layers extends so as to overlap an area extending from at least a part of a first disposition area in which the first transistor is disposed to a second disposition area in which the current output element is disposed in plan view of the semiconductor substrate.

Abstract: A power amplifying module includes a first input terminal, a second input terminal, a first power amplifier, a stage matching circuit, a bypass line, and a second power amplifier. The first input terminal receives a first input signal in a first operation mode. The second input terminal receives a second input signal in a second operation mode which is different from the first operation mode. The first power amplifier amplifies the first input signal and outputs a first amplified signal. The stage matching circuit is disposed downstream of the first power amplifier and receives the first amplified signal. The bypass line outputs the second input signal to the inside of the stage matching circuit not through the first power amplifier. The second power amplifier is disposed downstream of the stage matching circuit, and amplifies the first amplified signal or the second input signal and outputs a second amplified signal.

Abstract: There is provided an information processing apparatus including a processing unit that tracks a target on the basis of a captured image that has been captured by an imaging device and sensor information obtained by communication from a sensor that senses the target.

Abstract: A particle includes at least one or more kinds of substrate and lipid nanoparticles. The lipid nanoparticles are dispersed in the substrate and contain a physiologically active substance. The lipid nanoparticles are one or more kinds selected from liposomes, lipid emulsions, and solid lipid nanoparticles. A corresponding powder inhalant contains the particle. A production method for the particle includes granulating and drying, in which a suspension containing the substrate and the lipid nanoparticles are granulated and dried in a gas medium.

Abstract: Provided is a resist composition which contains a resin (A) and a solvent (B) that contains a compound (B1) represented by general formula (b-1), wherein the content of the active ingredients based on the total amount of the resist composition is 45% by mass or less. (In formula (b-1), R1 represents an alkyl group having from 1 to 10 carbon atoms.

Abstract: A power amplifier circuit includes a first transistor disposed on a semiconductor substrate; a second transistor disposed on the semiconductor substrate and configured to supply a bias current based on a first current which is a part of a control current to the first transistor; a third transistor disposed on the semiconductor substrate and having a collector configured to be supplied with a second current which is a part of the control current and an emitter configured to output a third current based on the second current; a first bump electrically connected to an emitter of the first transistor and disposed so as to overlap a first disposition area in which the first transistor is disposed in plan view of the semiconductor substrate; and a second bump disposed so as to overlap a second disposition area in which the third transistor is disposed in the plan view.

Abstract: Provided is a method for producing a diol represented by Formula (1), the method including using water as a solvent to carry out a cyclodehydration reaction of a 1,4-cyclohexanedione derivative represented by Formula (2) with a triol represented by Formula (3) to produce a diol represented by Formula (1). In Formula (1), R1 and R2 each independently denote a hydrocarbon group, and R3 each independently denotes a hydrogen atom, a heteroatom-containing group, a halogen atom-containing group, a linear alkyl group having from 1 to 6 carbon atoms, a branched alkyl group having from 3 to 6 carbon atoms, or a group including an aryl group and having from 6 to 12 carbon atoms.

Abstract: Provided is a method for producing a particle including forming a particle composition liquid into droplets where the particle composition liquid includes a physiologically active substance and at least two dispersants, and solidifying the droplets of the particle composition liquid in a manner that at least one of the at least two dispersants is locally present at the surface side of the particle.

Abstract: A power amplifier circuit includes a first transistor disposed on a semiconductor substrate; a second transistor that supplies a bias current based on a first current which is a part of a control current to the first transistor; a current output element in which a current flowing therethrough increases in accordance with a rise in temperature; and a wiring portion including a plurality of metal layers that are electrically connected to an emitter of the first transistor and that are stacked one on top of another so as to oppose the semiconductor substrate. At least one metal layer among the plurality of metal layers extends so as to overlap an area extending from at least a part of a first disposition area in which the first transistor is disposed to a second disposition area in which the current output element is disposed in plan view of the semiconductor substrate.

Abstract: A power amplifier circuit includes a first transistor disposed on a semiconductor substrate; a second transistor disposed on the semiconductor substrate and configured to supply a bias current based on a first current which is a part of a control current to the first transistor; a third transistor disposed on the semiconductor substrate and having a collector configured to be supplied with a second current which is a part of the control current and an emitter configured to output a third current based on the second current; a first bump electrically connected to an emitter of the first transistor and disposed so as to overlap a first disposition area in which the first transistor is disposed in plan view of the semiconductor substrate; and a second bump disposed so as to overlap a second disposition area in which the third transistor is disposed in the plan view.

Abstract: A power amplifying module includes a first input terminal, a second input terminal, a first power amplifier, a stage matching circuit, a bypass line, and a second power amplifier. The first input terminal receives a first input signal in a first operation mode. The second input terminal receives a second input signal in a second operation mode which is different from the first operation mode. The first power amplifier amplifies the first input signal and outputs a first amplified signal. The stage matching circuit is disposed downstream of the first power amplifier and receives the first amplified signal. The bypass line outputs the second input signal to the inside of the stage matching circuit not through the first power amplifier. The second power amplifier is disposed downstream of the stage matching circuit, and amplifies the first amplified signal or the second input signal and outputs a second amplified signal.