Patents by Inventor Hideyuki Shirae

Hideyuki Shirae has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Drugs having long-term retention in target tissue
    Publication number: 20030103934
    Abstract: The present invention relates to a polyethylene glycol-bound ligand in which polyethylene glycol is bound to a ligand having a binding affinity for a specific receptor or a specific protein (i.e.
    Type: Application
    Filed: September 30, 2002
    Publication date: June 5, 2003
    Applicant: AJINOMOTO CO. INC
    Inventors: Haruya Sato, Eiko Hayashi, Hideyuki Shirae
  • Method of producing 2',3'-dideoxyinosine
    Patent number: 4970148
    Abstract: A method of producing dideoxyinosine involving contacting as a substrate 2',3'-dideoxyadenosine with a microorganism which is capable of converting the substrate into 2',3'-dideoxyinosine.
    Type: Grant
    Filed: October 7, 1988
    Date of Patent: November 13, 1990
    Assignee: Ajinomoto Co., Inc.
    Inventors: Kenzo Yokozeki, Hideyuki Shirae, Katsunori Kobayashi, Hiroshi Shiragami, Yasuo Irie
  • Methods for producing ribose-1-phosphoric acid and ribavirin
    Patent number: 4968606
    Abstract: The present invention relates to methods for producing ribavirin utilizing microorganisms and a method for producing ribose-1-phosphoric acid which is a precursor of ribavirin. The methods involve contacting certain microorganisms with orotidine, orotidic acid, or salts thereof, and inorganic phosphoric acid or a salt thereof (to produce ribose-1-phosphoric acid), and further with 1,2,4-triazole-3-carboxamide or a salt thereof (to produce ribavirin) in an aqueous solvent.
    Type: Grant
    Filed: September 15, 1989
    Date of Patent: November 6, 1990
    Assignee: Ajinomoto Co., Inc.
    Inventors: Kenzo Yokozeki, Hideyuki Shirae, Koji Kubota
  • Process for purifying 2',3'-dideoxynucleosides
    Patent number: 4962193
    Abstract: A biological process for producing a 2',3'-dideoxynucleoside from 2',3'-dideoxyuridine is disclosed. the 2',3'-dideoxynucleoside can be purified readily using a porous nonpolar resin adsorbent.
    Type: Grant
    Filed: December 28, 1988
    Date of Patent: October 9, 1990
    Assignee: Ajinomoto Co., Inc.
    Inventors: Kenzo Yokozeki, Hideyuki Shirae, Hiroshi Shiragami, Yasuo Irie, Naohiko Yasuda, Masaru Otani, Toshiya Tanabe
  • Process for producing and purifying 2',3'-dideoxynucleosides, and process for producing 2',3'-dideoxy-2',3'-didehydronucleosides
    Patent number: 4835104
    Abstract: A biological process for producing a 2',3'-dideoxyncleoside from 2',3'-dideoxyuridine is disclosed. The 2',3'-dideoxynucleoside can be purified readily using a porous nonpolar resin adsorbent.
    Type: Grant
    Filed: May 9, 1988
    Date of Patent: May 30, 1989
    Assignee: Ajinomoto Co., Inc., Patent & Licensing Department
    Inventors: Kenzo Yokozeki, Hideyuki Shirae, Hiroshi Shiragami, Yasuo Irie, Naohiko Yasuda, Masaru Otani, Toshiya Tanabe