Patents by Inventor Hieu Trung Phan

Hieu Trung Phan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminodiphosphonate apolipoprotein E modulators
    Patent number: 7208481
    Abstract: The present invention relates to methods of use of aminodiphosphonate to modulate apolipoprotein E levels and the use of such compounds in therapy, including cardiovascular and neurological disease states.
    Type: Grant
    Filed: February 14, 2003
    Date of Patent: April 24, 2007
    Assignee: ILEX Products, Inc.
    Inventors: Hieu Trung Phan, Lân Mong Nguyen, Raymond Azoulay, Vinh Van Diep, Eric Joseph Niesor, Craig Leigh Bentzen, Yves Gyon Gellin, Anne Perez, Jean-Luc Thulliard
  • ?-substituted ?-aminoethyl phosphonate derivatives
    Patent number: 6872711
    Abstract: The present invention relates to novel ?-substituted-?-aminoethylphosphonate derivatives and their uses for lowering plasma levels of apo (a), Lp(a), apo B, apo B associated lipoproteins (low density lipoproteins and very low density lipoproteins) and for lowering plasma levels of total cholesterol.
    Type: Grant
    Filed: October 22, 2001
    Date of Patent: March 29, 2005
    Assignee: Ilex Oncology Research S.A.
    Inventors: Hieu Trung Phan, Lan Mong Nguyen, Vinh Van Diep, Raymond Azoulay, Eric Joseph Niesor, Craig Leigh Bentzen, Robert John Ife
  • &agr;-Substituted &bgr;-aminoethyl phosphonate derivatives
    Patent number: 6706698
    Abstract: The present invention relates to novel &agr;-substituted-&bgr;-aminoethylphosphonate and &agr;-substituted-&bgr;-aminovinylphosphonate derivatives and their uses for lowering plasma levels of apo (a), Lp(a), apo B, apo B associated lipoproteins (low density lipoproteins and very low density lipoproteins) and for lowering plasma levels of total cholesterol.
    Type: Grant
    Filed: September 26, 2001
    Date of Patent: March 16, 2004
    Assignee: Ilex Products, Inc.
    Inventors: Hieu Trung Phan, Lan Mong Nguyen, Vinh Van Diep, Raymond Azoulay, Harald Eschenhof, Eric Joseph Niesor, Craig Leigh Bentzen, Robert John Ife
  • Compounds and pharmaceutical compositions containing them
    Patent number: 6660724
    Abstract: Aminophosphonates alpha substituted by phenol groups of formula (I) have lipoprotein(a) lowering activity.
    Type: Grant
    Filed: April 3, 2000
    Date of Patent: December 9, 2003
    Assignee: Ilex Products, Inc.
    Inventors: Lan Mong Nguyen, Eric Niesor, Craig Leigh Bentzen, Hieu Trung Phan, Vinh Van Diep, Simon Floret, Raymond Azoulay, Alexandre Bulla, Yves Guyon-Gellin, Robert John Ife
  • Alpha-substituted beta-aminoethyl phosphonate derivatives
    Publication number: 20030114421
    Abstract: The present invention relates to novel &agr;-substituted-&bgr;-aminoethylphosphonate and &agr;-substituted-&bgr;-aminovinylphosphonate derivatives and their uses for lowering plasma levels of apo (a), Lp(a), apo B, apo B associated lipoproteins (low density lipoproteins and very low density lipoproteins) and for lowering plasma levels of total cholesterol.
    Type: Application
    Filed: September 4, 2002
    Publication date: June 19, 2003
    Inventors: Hieu Trung Phan, Lan Mong Nguyen, Vinh Van Diep, Raymond Azoulay, Harald Eschenhof, Eric Joseph Niesor, Craig Leigh Bentzen, Robert John Ife
  • Alpha-substituted beta-aminoethyl phosphonate derivatives
    Publication number: 20020111332
    Abstract: The present invention relates to novel &agr;-substituted-&bgr;-aminoethylphosphonate and &agr;-substituted-&bgr;-aminovinylphosphonate derivatives and their uses for lowering plasma levels of apo (a), Lp(a), apo B, apo B associated lipoproteins (low density lipoproteins and very low density lipoproteins) and for lowering plasma levels of total cholesterol.
    Type: Application
    Filed: September 26, 2001
    Publication date: August 15, 2002
    Inventors: Hieu Trung Phan, Lan Mong Nguyen, Vinh Van Diep, Raymond Azoulay, Harald Eschenhof, Eric Joseph Niesor, Craig Leigh Bentzen, Robert John Ife
  • Beta-substitued beta-aminoethyl phosphonate derivatives
    Publication number: 20020111488
    Abstract: The present invention relates to novel &bgr;-substituted-&bgr;-aminoethylphosphonate derivatives and their uses for lowering plasma levels of apo (a), Lp(a), apo B, apo B associated lipoproteins (low density lipoproteins and very low density lipoproteins) and for lowering plasma levels of total cholesterol.
    Type: Application
    Filed: October 22, 2001
    Publication date: August 15, 2002
    Inventors: Hieu Trung Phan, Lan Mong Nguyen, Vinh Van Diep, Raymond Azoulay, Eric Joseph Niesor, Craig Leigh Bentzen, Robert John Ife
  • Pharmaceutical aminophosphonic acid derivatives
    Publication number: 20020082423
    Abstract: Aminophosphonates alpha substituted by phenol groups, of formula (I) have lipoprotein(a) lowering activity.
    Type: Application
    Filed: September 4, 2001
    Publication date: June 27, 2002
    Applicant: SmithKline Beecham p.l.c. and Symphar
    Inventors: Lan Mong Nguyen, Hieu Trung Phan, Vinh Van Diep, Simon Floret, Raymond Azoulay, Eric Niesor, Craig Leigh Bentzen, Robert John Ife
  • Pharmaceutical aminophosphonic acid derivatives
    Patent number: 6303784
    Abstract: Aminophosphonates alpha substituted by phenol groups, of formula (I) have lipoprotein(a) lowering activity.
    Type: Grant
    Filed: June 18, 1999
    Date of Patent: October 16, 2001
    Assignees: SmithKline Beecham p.l.c., Symphar SA
    Inventors: Lan Mong Nguyen, Hieu Trung Phan, Vinh Van Diep, Simon Floret, Raymond Azoulay, Eric Niesor, Craig Leigh Bentzen, Robert John Ife
  • Use of phenol substituted diphosphonates as antineoplastic agents
    Patent number: 6127350
    Abstract: A method of treating or preventing neoplastic disease and a method of preventing transformation of a normal cell into a tumor cell by mutated ras activities, utilizing a compound of formula I are disclose.
    Type: Grant
    Filed: January 28, 1998
    Date of Patent: October 3, 2000
    Assignee: Symphar S.A.
    Inventors: Eric Niesor, Craig Leigh Bentzen, Lan Mong Nguyen, Jean-Luc Thuillard, Hieu Trung Phan, Jean Flach
  • Compounds and pharmaceutical compositions containing them
    Patent number: 6060464
    Abstract: Aminophosphonates alpha substituted by phenol groups of formula (I) have lipoprotein(a) lowering activity.
    Type: Grant
    Filed: April 3, 1998
    Date of Patent: May 9, 2000
    Assignees: SmithKline Beecham p.l.c., Symphar SA
    Inventors: Lan Mong Nguyen, Eric Niesor, Craig Leigh Bentzen, Hieu Trung Phan, Vinh Van Diep, Simon Floret, Raymond Azoulay, Alexandre Bulla, Yves Guyon-Gellin, Robert John Ife