Patents by Inventor Hikaru Kobayashi

Hikaru Kobayashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12070519
    Abstract: One composite composition of the present invention contains: a silicon fine particle; and a silicon suboxide (SiOX, wherein x is ½, 1, or 3/2) and/or a mixed composition of the silicon suboxide and silicon dioxide, at least partially covering the surface of the silicon fine particle.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: August 27, 2024
    Assignees: KIT CO. LTD, BOSQUET SILICON CORP.
    Inventors: Hikaru Kobayashi, Yuki Kobayashi
  • Publication number: 20240269165
    Abstract: An object is to provide a pharmaceutical or the like that can prevent or treat non-alcoholic fatty liver disease, pain associated with inactivity, or acute pancreatitis. [Solving Means] When silicon small particles are orally administered or placed on a skin or a mucous membrane, non-alcoholic fatty liver disease, pain associated with inactivity, and acute pancreatitis can be prevented or treated. The silicon small particles are particles each of which generates hydrogen when brought into contact with an aqueous solution having a pH of 7 or more. Provided is a preventive or therapeutic agent, pharmaceutical composition, medical device, food, or beverage comprising the silicon small particles for non-alcoholic fatty liver disease, pain associated with inactivity, or acute pancreatitis. The silicon small particles are suitably silicon fine particles and/or aggregates of the silicon fine particles.
    Type: Application
    Filed: May 31, 2022
    Publication date: August 15, 2024
    Applicant: Osaka University
    Inventors: Shoichi Shimada, Yoshihisa Koyama, Makoto Kondo, Noriyoshi Usui, Hikaru Kobayashi, Yuki Kobayashi
  • Patent number: 12054571
    Abstract: Provided are a host-group-containing polymerizable monomer usable as a starting material for producing a macromolecular material with a high degree of freedom in material design, and excellent toughness and strength; a macromolecular material produced using the host-group-containing polymerizable monomer; and a method for producing the macromolecular material. The host-group-containing polymerizable monomer according to the present invention is a host-group-containing polymerizable monomer, and the host group is a monovalent group formed by removing one hydrogen atom or hydroxy group from a cyclodextrin derivative. The cyclodextrin derivative has such a structure that the hydrogen atom of at least one hydroxy group of a cyclodextrin is replaced with a group selected from the group consisting of a hydrocarbon group, an acyl group, and —CONHR wherein R represents a methyl group or an ethyl group.
    Type: Grant
    Filed: March 1, 2018
    Date of Patent: August 6, 2024
    Assignee: OSAKA UNIVERSITY
    Inventors: Akira Harada, Hiroyasu Yamaguchi, Yoshinori Takashima, Suguru Nomimura, Hikaru Aramoto, Ryohei Ikura, Yuichiro Kobayashi, Yukie Nakamitsu
  • Patent number: 12037326
    Abstract: A compound represented by Formula (I), or a salt thereof: wherein, R1 represents an unsubstituted or substituted C1-6 alkylthio group, or the like; A1 represents a nitrogen atom or CH; A2 represents a nitrogen atom or CR2; R2 and R3 each independently represents a hydrogen atom, an unsubstituted or substituted C6-10 aryl group, an unsubstituted or substituted 3- to 6-membered heterocyclyl group, or the like; B1 and B2 each independently represents a nitrogen atom or CR5, with the proviso that B1 and B2 do not represent CR5 at the same time, wherein R5 represents a hydrogen atom, an unsubstituted or substituted C1-6 alkyl group, or the like; R4 represents an unsubstituted or substituted C1-6 alkyl group, or the like, and R4 binds to any one of nitrogen atoms forming an imidazole ring or a triazole ring; and Ar represents an unsubstituted or substituted C6-10 aryl group or the like.
    Type: Grant
    Filed: October 13, 2021
    Date of Patent: July 16, 2024
    Assignee: Nippon Soda Co., Ltd.
    Inventors: Keita Sakanishi, Takao Iwasa, Hikaru Aoyama, Norifumi Sakiyama, Daisuke Ushijima, Maki Matsui, Tomomi Kobayashi
  • Publication number: 20240189345
    Abstract: An intestinal bacteria reducing agent of the present invention is a reducing agent which contains silicon particles or silicon fine particles and reduces the number of bacteria in the intestine. The intestinal bacteria reducing agent can reduce the number of bacteria in the intestine by a new action that cannot be explained by the heretofore known hydrogen generating capability of silicon particles or silicon fine particles, that is, the capability of eliminating hydroxyl radicals.
    Type: Application
    Filed: January 17, 2022
    Publication date: June 13, 2024
    Applicant: Osaka University
    Inventors: Hisako KAYAMA, Kiyoshi TAKEDA, Hikaru KOBAYASHI, Yuki KOBAYASHI
  • Patent number: 11951125
    Abstract: One drug (solid preparation) 100 of the present invention is a drug for a disease of kidney that contains a silicon fine particle, an aggregate of the silicon fine particles, or a crystal grain of silicon having a hydrogen-generating ability. Hydrogen generated from the silicon fine particle in the drug can contribute to the prevention and/or treatment of the kidney disease.
    Type: Grant
    Filed: April 21, 2021
    Date of Patent: April 9, 2024
    Assignee: OSAKA UNIVERSITY
    Inventors: Hikaru Kobayashi, Yuki Kobayashi, Ryoichi Imamura, Norio Nonomura
  • Publication number: 20240059557
    Abstract: An exemplary hydrogen production apparatus 100 according to the present invention includes a grinding unit 10 configured to grind a silicon chip or a silicon grinding scrap 1 to form silicon fine particles 2, and a hydrogen generator 70 configured to generate hydrogen by causing the silicon fine particles 2 to contact with as well as disperse in, or to contact with or dispersed in water or an aqueous solution. The hydrogen production apparatus 100 can achieve reliable production of a practically adequate amount of hydrogen from a start material of silicon chips or silicon grinding scraps that are ordinarily regarded as waste. The hydrogen production apparatus thus effectively utilizes the silicon chips or the silicon grinding scraps so as to contribute to environmental protection as well as to significant reduction in cost for production of hydrogen that is utilized as an energy source in the next generation.
    Type: Application
    Filed: November 1, 2023
    Publication date: February 22, 2024
    Inventors: Hikaru KOBAYASHI, Toru HIGO, Yayoi KANATANI
  • Patent number: 11840450
    Abstract: An exemplary hydrogen production apparatus 100 according to the present invention includes a grinding unit 10 configured to grind a silicon chip or a silicon grinding scrap 1 to form silicon fine particles 2, and a hydrogen generator 70 configured to generate hydrogen by causing the silicon fine particles 2 to contact with as well as disperse in, or to contact with or dispersed in water or an aqueous solution. The hydrogen production apparatus 100 can achieve reliable production of a practically adequate amount of hydrogen from a start material of silicon chips or silicon grinding scraps that are ordinarily regarded as waste. The hydrogen production apparatus thus effectively utilizes the silicon chips or the silicon grinding scraps so as to contribute to environmental protection as well as to significant reduction in cost for production of hydrogen that is utilized as an energy source in the next generation.
    Type: Grant
    Filed: May 7, 2021
    Date of Patent: December 12, 2023
    Assignee: NISSHIN KASEI CO., LTD.
    Inventors: Hikaru Kobayashi, Toru Higo, Yayoi Kanatani
  • Publication number: 20230355665
    Abstract: One solid preparation of the present invention mainly includes silicon fine particles, and has a capability of generating hydrogen. In addition, one specific example of the solid preparation mainly includes silicon fine particles having a crystallite diameter principally of 1 nm or more and 100 nm or less, and exhibits a capability of generating hydrogen in an amount of 3 ml/g or more when brought into contact with a water-containing liquid having a pH value of 7 or more. In this solid preparation, hydrogen is generated when the silicon fine particles are brought into contact with a water-containing liquid having a pH value of 7 or more. Therefore, taking advantage of the characteristics of the solid preparation, generation of hydrogen is promoted in, for example, a gastrointestinal tract where the pH value is 7 or more due to secretion of pancreatic fluid after passage through the stomach after oral ingestion.
    Type: Application
    Filed: July 20, 2023
    Publication date: November 9, 2023
    Applicants: BOSQUET SILICON CORP., KIT Co. Ltd.
    Inventors: Hikaru Kobayashi, Yuki Kobayashi
  • Publication number: 20230320348
    Abstract: One compound according to the present invention contains silicon fine particles having a capability of generating hydrogen or aggregates of the silicon fine particles. The compound that contains the silicon fine particles or the aggregates having a capability of generating hydrogen is capable of generating hydrogen in the body of, for example, an animal that has ingested the compound. For a plant, the compound can be disposed or charged into, for example, moisture (water-containing liquid) or fertilizer to be provided to the plant, to supply the plant with hydrogen generated from the compound.
    Type: Application
    Filed: June 5, 2023
    Publication date: October 12, 2023
    Applicants: BOSQUET SILICON CORP., KIT Co., Ltd.
    Inventors: Hikaru Kobayashi, Yuki Kobayashi
  • Patent number: 11752170
    Abstract: One solid preparation of the present invention mainly includes silicon fine particles, and has a capability of generating hydrogen. In addition, one specific example of the solid preparation mainly includes silicon fine particles having a crystallite diameter principally of 1 nm or more and 100 nm or less, and exhibits a capability of generating hydrogen in an amount of 3 ml/g or more when brought into contact with a water-containing liquid having a pH value of 7 or more. In this solid preparation, hydrogen is generated when the silicon fine particles are brought into contact with a water-containing liquid having a pH value of 7 or more. Therefore, taking advantage of the characteristics of the solid preparation, generation of hydrogen is promoted in, for example, a gastrointestinal tract where the pH value is 7 or more due to secretion of pancreatic fluid after passage through the stomach after oral ingestion.
    Type: Grant
    Filed: February 24, 2022
    Date of Patent: September 12, 2023
    Assignees: BOSQUET SILICON CORP., KIT Co., Ltd.
    Inventors: Hikaru Kobayashi, Yuki Kobayashi
  • Patent number: 11707063
    Abstract: One compound (100) according to the present invention contains silicon fine particles having a capability of generating hydrogen or aggregates of the silicon fine particles. The compound that contains the silicon fine particles or the aggregates having a capability of generating hydrogen is capable of generating hydrogen in the body of, for example, an animal that has ingested the compound. For a plant, the compound can be disposed or charged into, for example, moisture (water-containing liquid) or fertilizer to be provided to the plant, to supply the plant with hydrogen generated from the compound.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: July 25, 2023
    Assignees: BOSQUET SILICON CORP., KIT Co., Ltd.
    Inventors: Hikaru Kobayashi, Yuki Kobayashi
  • Patent number: 11683944
    Abstract: A laminate which allows to obtain an organic thin-film solar cell having excellent output characteristics and transparency is provided. The laminate as above has a titanium oxide layer that is disposed on the member serving as a light-transmissive electrode layer and serves as an electron transport layer. The titanium oxide layer has a thickness of not less than 1.0 nm and not more than 200.0 nm. The titanium oxide layer contains indium oxide and metallic indium, InOx/Ti is not less than 0.50 and not more than 20.00 in atomic ratio, and InM/Ti is less than 0.100 in atomic ratio, where an elemental titanium content is represented by Ti, an indium oxide content is represented by InOx, and a metallic indium content is represented by InM.
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: June 20, 2023
    Assignees: JFE Steel Corporation, National University Corporation Hokkaido University
    Inventors: Mikito Suto, Hiroyuki Masuoka, Akira Matsuzaki, Hiroki Habazaki, Hikaru Kobayashi
  • Publication number: 20230157934
    Abstract: A layered solid formulation as one hydrogen supply material according to the present invention includes silicon fine particles having a capability of generating hydrogen and aggregates of the silicon fine particles, and a physiologically acceptable medium that gets contact with the silicon fine particles or the aggregates thereof. The hydrogen supply material is a hydrogen supply material for bringing the hydrogen into contact with the skin and/or the mucous membrane through the medium.
    Type: Application
    Filed: December 28, 2022
    Publication date: May 25, 2023
    Applicants: BOSQUET SILICON CORP., KIT Co. Ltd.
    Inventors: Hikaru Kobayashi, Yuki Kobayashi
  • Patent number: 11583483
    Abstract: A layered solid formulation (100a) as one hydrogen supply material (200) according to the present invention includes silicon fine particles having a capability of generating hydrogen and aggregates of the silicon fine particles, and a physiologically acceptable medium (90b) that gets contact with the silicon fine particles or the aggregates thereof. The hydrogen supply material (200) is a hydrogen supply material for bringing the hydrogen into contact with the skin and/or the mucous membrane through the medium (90b).
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: February 21, 2023
    Assignees: BOSQUET SILICON CORP., KIT Co., Ltd.
    Inventors: Hikaru Kobayashi, Yuki Kobayashi
  • Publication number: 20220336763
    Abstract: A laminate which allows to obtain an organic thin-film solar cell having excellent output characteristics and transparency is provided. The laminate as above has a titanium oxide layer that is disposed on the member serving as a light-transmissive electrode layer and serves as an electron transport layer. The titanium oxide layer has a thickness of not less than 1.0 nm and not more than 200.0 nm. The titanium oxide layer contains indium oxide and metallic indium, InOx/Ti is not less than 0.50 and not more than 20.00 in atomic ratio, and InM/Ti is less than 0.100 in atomic ratio, where an elemental titanium content is represented by Ti, an indium oxide content is represented by InOx, and a metallic indium content is represented by InM.
    Type: Application
    Filed: September 28, 2020
    Publication date: October 20, 2022
    Applicants: JFE Steel Corporation, NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
    Inventors: Mikito Suto, Hiroyuki Masuoka, Akira Matsuzaki, Hiroki Habazaki, Hikaru Kobayashi
  • Publication number: 20220175826
    Abstract: One solid preparation of the present invention mainly includes silicon fine particles, and has a capability of generating hydrogen. In addition, one specific example of the solid preparation mainly includes silicon fine particles having a crystallite diameter principally of 1 nm or more and 100 nm or less, and exhibits a capability of generating hydrogen in an amount of 3 ml/g or more when brought into contact with a water-containing liquid having a pH value of 7 or more. In this solid preparation, hydrogen is generated when the silicon fine particles are brought into contact with a water-containing liquid having a pH value of 7 or more. Therefore, taking advantage of the characteristics of the solid preparation, generation of hydrogen is promoted in, for example, a gastrointestinal tract where the pH value is 7 or more due to secretion of pancreatic fluid after passage through the stomach after oral ingestion.
    Type: Application
    Filed: February 24, 2022
    Publication date: June 9, 2022
    Applicants: BOSQUET SILICON CORP., KIT Co. Ltd.
    Inventors: Hikaru Kobayashi, Yuki Kobayashi
  • Patent number: 11311572
    Abstract: One solid preparation of the present invention mainly includes silicon fine particles, and has a capability of generating hydrogen. In addition, one specific example of the solid preparation mainly includes silicon fine particles having a crystallite diameter principally of 1 nm or more and 100 nm or less, and exhibits a capability of generating hydrogen in an amount of 3 ml/g or more when brought into contact with a water-containing liquid having a pH value of 7 or more. In this solid preparation, hydrogen is generated when the silicon fine particles are brought into contact with a water-containing liquid having a pH value of 7 or more. Therefore, taking advantage of the characteristics of the solid preparation, generation of hydrogen is promoted in, for example, a gastrointestinal tract where the pH value is 7 or more due to secretion of pancreatic fluid after passage through the stomach after oral ingestion.
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: April 26, 2022
    Assignees: BOSQUET SILICON CORP., KIT Co. Ltd.
    Inventors: Hikaru Kobayashi, Yuki Kobayashi
  • Publication number: 20220088064
    Abstract: One drug (preparation) of the present invention is a drug for a reproductive disorder containing a silicon fine particle, an aggregate of silicon fine particles or a crystal grain of silicon having a hydrogen-generating ability. Hydrogen generated from the silicon fine particle in the drug can contribute to the prevention and/or treatment of reproductive disorder.
    Type: Application
    Filed: November 29, 2019
    Publication date: March 24, 2022
    Applicant: OSAKA UNIVERSITY
    Inventors: Ryoichi IMAMURA, Hikaru KOBAYASHI, Yuki KOBAYASHI, Shinichiro FUKUHARA, Yusuke INAGAKI, Norio NONOMURA
  • Publication number: 20220037605
    Abstract: An assembly of nanoparticles includes metal oxide, the nanoparticles including zinc (Zn) and silicon (Si). In addition, the nanoparticles have an atomic ratio of Zn/(Zn+Si) in a range of 0.3 to 0.95. Further, the nanoparticles have an equivalent circular particle diameter in a range of 1 nm to 20 nm.
    Type: Application
    Filed: October 21, 2021
    Publication date: February 3, 2022
    Applicant: AGC Inc.
    Inventors: Satoru WATANABE, Yoshitake TODA, Kunio MASUMO, Nao ISHIBASHI, Nobuhiro NAKAMURA, Shimpei MORITA, Hikaru KOBAYASHI