Patents by Inventor Hila Amir-Kroll

Hila Amir-Kroll has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccines comprising multimeric HSP60 peptide carriers
    Patent number: 8414899
    Abstract: The present invention provides improved vaccine compositions having enhanced immunogenicity and methods of using same. The compositions and methods include immunogenic conjugates containing peptide carriers derived from heat shock protein 60 (HSP60). The known synthetic peptide carrier, p458, provides significantly improved immunogenicity when provided as a multimeric conjugate comprising a plurality of peptide carrier units conjugated to each antigen. Cell vaccine compositions comprising antigen presenting cells loaded with multimeric p458 conjugates are also provided.
    Type: Grant
    Filed: April 11, 2007
    Date of Patent: April 9, 2013
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Irun R. Cohen, Hila Amir-Kroll, Noam Cohen, Gabriel Nussbaum
  • VACCINES COMPRISING MULTIMERIC HSP60 PEPTIDE CARRIERS
    Publication number: 20090269370
    Abstract: The present invention provides improved vaccine compositions having enhanced immunogenicity and methods of using same. The compositions and methods include immunogenic conjugates containing peptide carriers derived from heat shock protein 60 (HSP60). The known synthetic peptide carrier, p458, provides significantly improved immunogenicity when provided as a multimeric conjugate comprising a plurality of peptide carrier units conjugated to each antigen. Cell vaccine compositions comprising antigen presenting cells loaded with multimeric p458 conjugates are also provided.
    Type: Application
    Filed: April 11, 2007
    Publication date: October 29, 2009
    Applicant: YEDA Research and Development Co. Ltd. at the Weizmann Institute of Science
    Inventors: Irun R. Cohen, Hila Amir-Kroll, Noam Cohen, Gabriel Nussbaum