Patents by Inventor Hilda E. Smith

Hilda E. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Streptococcus suis vaccines and diagnostic tests
    Publication number: 20020055168
    Abstract: The invention relates to Streptococcus suis infection in pigs, vaccines directed against those infections and tests for diagnosing Streptococcus suis infections. The invention provides an isolated or recombinant nucleic acid encoding a capsular gene cluster of Streptococcus suis or a gene or gene fragment derivated thereof. The invention further provides a nucleic acid probe or primer allowing species or serotype specific detection of Streptococcus suis. The invention also provides a Streptococcus suis antigen and vaccine derived thereof.
    Type: Application
    Filed: January 22, 2001
    Publication date: May 9, 2002
    Inventor: Hilda E. Smith
  • Virulence-encoding DNA sequences of Strepococcus suis and related products and methods
    Patent number: 5610011
    Abstract: The invention provides DNA sequences which code for polypeptides which are characteristic for the virulence of the pathogenic bacterium Streptococcus suis and parts thereof, and polypeptides and antibodies derived therefrom. The sequences code for a polypeptide of 90,000-120,000 daltons or a polypeptide of higher molecular weight containing such a polypeptide, and for a polypeptide of 135,000-136,000 daltons (muramidase released protein), or parts thereof. The sequences themselves, and also the polypeptides and antibodies derived therefrom, are used for diagnosis of and protection against infection by S. suis in mammals, including man.
    Type: Grant
    Filed: September 20, 1993
    Date of Patent: March 11, 1997
    Assignee: Centraal Diergeneeskundig Instituut
    Inventors: Hilda E. Smith, Uri Vecht