Patents by Inventor Hilde De Reuse

Hilde De Reuse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of inhibiting
    Patent number: 7517666
    Abstract: This application relates to methods of screening molecules capable of inhibiting the survival of Helicobacter pylori in vivo by specifically inhibiting the activity of UreI, to the molecules identified by these methods, and to the use of these molecules to treat or prevent H. pylori infection.
    Type: Grant
    Filed: March 2, 2005
    Date of Patent: April 14, 2009
    Assignee: Institut Pasteur
    Inventors: Hilde De Reuse, Stéphane Skouloubris, Valérie Cussac, Agnés Labigne
  • Methods of inhibiting Helicobacter pylori
    Publication number: 20050176077
    Abstract: This application relates to methods of screening molecules capable of inhibiting the survival of Helicobacter pylori in vivo by specifically inhibiting the activity of UreI, to the molecules identified by these methods, and to the use of these molecules to treat or prevent H. pylori infection.
    Type: Application
    Filed: March 2, 2005
    Publication date: August 11, 2005
    Inventors: Hilde De Reuse, Stephane Skouloubris, Valerie Cussac, Agnes Labigne
  • Methods of inhibiting helicobacter pylori
    Patent number: 6762051
    Abstract: This invention relates to methods of screening molecules capable of inhibiting the survival of Helicobacter pylori in vivo by specifically inhibiting the activity of UreI, to the molecules identified by these methods, and to the use of these molecules to treat or prevent H. pylori infection.
    Type: Grant
    Filed: December 22, 2000
    Date of Patent: July 13, 2004
    Assignee: Institut Pasteur
    Inventors: Hilde De Reuse, Stéphane Skouloubris, Valérie Cussac, Agnés Labigne
  • Methods of inhibiting Helicobacter pylori
    Publication number: 20040115772
    Abstract: A method of treating or preventing Helicobacter infection in humans or animals comprising the step of administering a molecule, such as a molecule that can interact with UreI, capable of inhibiting the growth or survival of Helicobacter in vivo to a human or animal in need of such treatment.
    Type: Application
    Filed: November 25, 2003
    Publication date: June 17, 2004
    Inventors: Hilde De Reuse, Stephane Skouloubris, Valerie Cussac, Agnes Labigne
  • Anti-sigma28 factors in Helicobacter pylori, Campylobacter jejuni and Pseudomonas aeruginosa and applications thereof
    Publication number: 20020192796
    Abstract: Disclosed are polypeptides named HP1122, Cj1464 and PA3351 which are the anti-&sgr;28 factor of Helicobacter pylori, Campylobacter jejuni and Pseudomonas aeruginosa, respectively and fragments and variants thereof. Also disclosed is a polypeptide named SID1122 which is the domain of Helicobacter pylori's HP1122 polypeptide involved in a specific interaction with Helicobacter pylori &sgr;28 (HP1032) and which has an anti-&sgr;28 factor activity.
    Type: Application
    Filed: January 31, 2002
    Publication date: December 19, 2002
    Inventors: Pierre Legrain, Frederic Colland, Jean-Christophe Rain, Agnes Labigne, Hilde De Reuse
  • Methods of inhibiting helicobacter pylori
    Publication number: 20020102269
    Abstract: This invention relates to methods of screening molecules capable of inhibiting the survival of Helicobacter pylori in vivo by specifically inhibiting the activity of UreI, to the molecules identified by these methods, and to the use of these molecules to treat or prevent H. pylori infection.
    Type: Application
    Filed: December 22, 2000
    Publication date: August 1, 2002
    Inventors: Hilde De Reuse, Stephane Skouloubris, Valerie Cussac, Agnes Labigne
  • Methods of inhibiting Helicobacter pylori
    Patent number: 6416968
    Abstract: This invention relates to methods of screening molecules capable of inhibiting the survival of Helicobacter pylori in vivo by specifically inhibiting the activity of UreI, to the molecules identified by these methods, and to the use of these molecules to treat or prevent H. pylori infection.
    Type: Grant
    Filed: August 23, 2000
    Date of Patent: July 9, 2002
    Assignee: Institut Pasteur
    Inventors: Hilde De Reuse, Stéphane Skouloubris, Valérie Cussac, Agnès Labigne
  • Helicobacter aliphatic amidase AmiE polypeptides, and DNA sequences encoding those polypeptides
    Patent number: 6248551
    Abstract: This invention relates to Helicobacter species aliphatic amidase AmiE polypeptides, the DNA encoding those polypeptides and transformed microorganisms capable of expressing those polypeptides. This invention also relates to the use of Helicobacter sp. (particularly Helicobacter pylori) amidase AmiE polypeptides and antibodies specific for those polypeptides in immunogenic, therapeutic, and diagnostic applications. The invention additionally relates to processes of producing Helicobacter species aliphatic amidase AmiE polypeptides and intermediates useful in the production of those polypeptides.
    Type: Grant
    Filed: February 23, 1998
    Date of Patent: June 19, 2001
    Assignee: Institut Pasteur
    Inventors: Hilde De Reuse, Stephane Skouloubris, Agnes Labigne
  • Methods of inhibiting Helicobacter pylori
    Patent number: 6190667
    Abstract: This invention relates to methods of screening molecules capable of inhibiting the survival of Helicobacter pylori in vivo by specifically inhibiting the activity of UreI, to the molecules identified by these methods, and to the use of these molecules to treat or prevent H. pylori infection.
    Type: Grant
    Filed: June 30, 1998
    Date of Patent: February 20, 2001
    Assignee: Institut Pasteur
    Inventors: Hilde De Reuse, Stéphane Skouloubris, Valérie Cussac, Agnès Labigne