Patents by Inventor Hildebert Wagner

Hildebert Wagner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7470441
    Abstract: The present invention provides pharmaceutical compositions comprising Mucuna pruriens seeds or one or more Mucuna pruriens seed components, substances, fractions or mixtures or substances obtained therefrom. Furthermore, the invention relates to the use of Mucuna pruriens seed powder or one or more Mucuna pruriens components, substances, fractions or mixtures or substances obtained therefrom for the preparation of a pharmaceutical composition for preventing, alleviating or treating neurological diseases. Additionally, the invention relates to the use of Mucuna pruriens seeds for the preparation of a pharmaceutical composition for neuroprotection or neurostimulation and to methods of preparing extracts of Mucuna pruriens which can be used for the preparation of a pharmaceutical composition for treating neurological diseases.
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: December 30, 2008
    Assignee: Phytrix AG
    Inventors: Rob Van Der Giessen, C. Warren Olanow, Andrew Lees, Hildebert Wagner
  • Publication number: 20060165822
    Abstract: The present invention provides pharmaceutical compositions comprising Mucuna pruriens seeds or one or more Mucuna pruriens seed components, substances, fractions or mixtures or substances obtained therefrom. Furthermore, the invention relates to the use of Mucuna pruriens seed powder or one or more Mucuna pruriens components, substances, fractions or mixtures or substances obtained therefrom for the preparation of a pharmaceutical composition for preventing, alleviating or treating neurological diseases. Additionally, the invention relates to the use of Mucuna pruriens seeds for the preparation of a pharmaceutical composition for neuroprotection or neurostimulation and to methods of preparing extracts of Mucuna pruriens which can be used for the preparation of a pharmaceutical composition for treating neurological diseases.
    Type: Application
    Filed: October 2, 2003
    Publication date: July 27, 2006
    Applicant: Phytrix AG
    Inventors: Rob Van Der Giessen, C Olanow, Andrew Lees, Hildebert Wagner
  • Patent number: 6586015
    Abstract: The present invention relates to the use of Phyllanthus for preventing or treating connective tissue proliferations, for maintaining the level of reduced glutathione, for inhibiting lipopolysaccharide (LPS)-induced nitric oxide synthase (NOS) and for inhibiting expression of the cyclooxygenase (COX-2) protein.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: July 1, 2003
    Assignee: Phytrix AG
    Inventors: Rolf Gebhardt, Angelika M. Vollmar, Michael P. Manns, Matthias Bahr, Hildebert Wagner, Gayane Hrachia Buniatian
  • Patent number: 5481043
    Abstract: Certain new phenone derivatives of the formula (I) ##STR1## in which R.sup.1 =CH.sub.3,R.sup.2 =H, Cl, Br, I, methyl, hydroxy, methoxy, propoxy, propoxy or ethoxy;R.sup.3 =H or .beta.-D-glykosyl;R.sup.4 =H, Cl, Br, I, methyl, hydroxy, methoxy, propoxy, iso-propoxy or ethoxy;R.sup.5 =H or hydroxy,and the pharmaceutically acceptable salts, ethers and esters thereof, with the exception of the compounds 4-hydroxyacetophenone, 4-hydroxy-3-methoxy-acetophenone, 4-glucopyranosyloxy-acetophenone, 4-glucopyranosyloxy-3-methoxyacetophenone, 4-galactopyranosyloxy-3-methoxy-acetophenone, 4-glucopyranosyloxy-3,5-dimethoxy-acetophenone and galactopyranosyloxy-3,5-dimethoxy-acetophenone and a method for manufacturing them and pharmaceutical preparations containing them. The invention also concerns pharmaceutical preparations containing at least one compound of the formula (II) ##STR2## in which R.sup.1 denotes H, OH, alkoxy or C.sub.1-8 alkyl;R.sup.2 denotes H or C.sub.1-4 alkoxy;R.sup.3 denotes OH or a .beta.
    Type: Grant
    Filed: February 18, 1992
    Date of Patent: January 2, 1996
    Assignee: Plantamed Arzneimittel GmbH
    Inventors: Hildebert Wagner, Walter Dorsch, Hermann Stuppner, Sandor Antus
  • Patent number: 5321045
    Abstract: The invention concerns thiosulphinic acid derivatives, medicaments containing these compounds and their use in medicine. It has been found that thiosulphinic acid derivatives display outstanding inflammation-inhibiting properties. The compounds prove to be especially advantageous in the treatment of PAF-induced inflammatory processes of the bronchial area.
    Type: Grant
    Filed: March 14, 1989
    Date of Patent: June 14, 1994
    Assignee: Boehringer Mannheim GmbH
    Inventors: Walter Dorsch, Hildebert Wagner
  • Patent number: 5260335
    Abstract: The invention concerns pharmaceutical preparations containing at least one of the following compounds as an active ingredient either alone or in any desired combination: gallic acid, methyl gallate and compounds of the general formula______________________________________ ##STR1## R.sub.1 R.sub.2 R.sub.3 R.sub.4 ______________________________________ 1 galloyl galloyl galloyl H 2 galloyl digalloyl galloyl H 3 galloyl galloyl digalloyl H 4 digalloyl galloyl galloyl H 5 galloyl galloyl galloyl galloyl ______________________________________ with galloyl signifying the radical ##STR2## and diagalloyl signifying the radical ##STR3## - and the pharmaceutically acceptable salts, ethers and esters thereof. The invention further relates to a method for isolating the aforementioned compounds from the plant Galphimia Glauca. The drugs according to the invention are effective antiphlogistic agents.
    Type: Grant
    Filed: February 18, 1992
    Date of Patent: November 9, 1993
    Assignee: Plantamed Arzneimittel GmbH
    Inventors: Hildebert Wagner, Walter Dorsch
  • Patent number: 4940725
    Abstract: Tetra- and pentacyclic oxindole alkaloids, in particular the alloisopteropodine, isomer A, a pentacyclic oxindole alkaloid, are suitable for the unspecific stimulation of the immunologic system, which has been proved by a substantial percental phagocytosis increase in the granulocytic test according to BRANDT (in vitro), a substantial percental increase of the CL-response in the chemiluminescence test (in vitro) and a high increase of the phagocytosis activity of tissue macrophages of the reticoloendothelial system in the carbon-clearence-test (CCT) according to BIOZZI.
    Type: Grant
    Filed: April 3, 1989
    Date of Patent: July 10, 1990
    Assignee: Klaus Keplinger
    Inventors: Klaus Keplinger, Hildebert Wagner, Barbara Kreutzkamp
  • Patent number: 4857512
    Abstract: The present invention pertains to plant polysaccharides acting on the immune system and a process for isolating the polysaccharides from plant cell cultures. The purified polysaccharides can be used as drugs, specifically as immunomodulators or immune mediators, in animal medicine.
    Type: Grant
    Filed: November 21, 1986
    Date of Patent: August 15, 1989
    Assignee: Lomapharm, Rudolf Lohmann GmbH KG, Pharmazeutische Fabrik
    Inventors: Hildebert Wagner, Meinhart H. Zenk, Holger Ott
  • Patent number: 4844901
    Abstract: Tetra- and pentacyclic oxindole alkaloids, in particular the alloisopteropodine, isomer A, a pentacyclic oxindole alkaloid, are suitable for the unspecific stimulation of the immunologic system, which has been proved by a substantially percental phagocytosis increase in the granulocytic test according to BRANDT (in vitro), a substantial percental increase of the CL-response in the chemiluminescence test (in vitro) and a high increase of the phagocytosis activity of tissue macrophages of the reticoloendothelial system in the carbon-clearence-test (CCT) according to BIOZZI.
    Type: Grant
    Filed: May 16, 1988
    Date of Patent: July 4, 1989
    Assignee: Klaus Keplinger
    Inventors: Klaus Keplinger, Hildebert Wagner, Barbara Kreutzkamp