Patents by Inventor Hildegard Nimmesgern

Hildegard Nimmesgern has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combination preparation for use in dementia
    Patent number: 6037347
    Abstract: The invention relates to a composition which is a pharmaceutical combination preparation comprising a compound which has an acetylcholinesterase-inhibitory action or exhibits muscarinergic action and a compound which increases the endogenous extracellular adenosine level, wherein the combination preparation is suitable for the treatment of dementia. The invention further relates to a process for the production of the combination preparation. The invention additionally relates to a process for treating patients in need of suitable therapy with the combination preparation.
    Type: Grant
    Filed: February 25, 1998
    Date of Patent: March 14, 2000
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Peter Schubert, Hildegard Nimmesgern, Karl Rudolphi
  • Substituted pyrimidine derivatives, a process for the preparation thereof and the use thereof as reagents
    Patent number: 5215990
    Abstract: Pyrimidine derivatives of the formula I ##STR1## in which R.sup.1, R.sup.2, X and Y have the stated meaning, the salts thereof and a process for the preparation thereof are described. Because of their sorbitol-accumulating activity, they are suitable for use as reagents for an advantageous pharmacological screening model for testing aldose reductase inhibitors.
    Type: Grant
    Filed: August 8, 1991
    Date of Patent: June 1, 1993
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Karl Geisen, Roland Utz, Hildegard Nimmesgern, Hans-Jochen Lang
  • Piperazine substituted pyrimidine derivatives and physiologically tolerated salts thereof
    Patent number: 5138058
    Abstract: Pyrimidine derivatives of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the indicated meanings, the salts thereof, and a process for the preparation thereof are described. Because of their sorbitol-accumulating activity, they are suitable as a tool in a pharmacological screening model for aldose reductase inhibitors.
    Type: Grant
    Filed: February 20, 1990
    Date of Patent: August 11, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Karl Geisen, Hans-Jochen Lang, Hildegard Nimmesgern, Klaus Weidmann
  • Substituted thienoimidazole derivatives
    Patent number: 5114955
    Abstract: Substituted thienoimidzaole derivatives, processes for their preparation, pharmaceutical preparations containing them and their use as inhibitors of gastric acid secretion.The invention relates to substituted thienoimidazole derivatives of the formula ##STR1## in which A stands for ##STR2## T denotes --S--, --SO-- or --SO.sub.2 --, R.sup.7 denotes a substituted aryloxy or aralkoxy radical and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.8 have the meanings indicated in the description, processes for their preparation, pharmaceutical preparations containing them and their use as medicaments.
    Type: Grant
    Filed: November 10, 1988
    Date of Patent: May 19, 1992
    Assignee: Hoechst Aketiengesellschaft
    Inventors: Hans-Jochen Lang, Klaus Weidmann, Karl-Heinz Scheunemann, Hildegard Nimmesgern, Robert Rippel, Andreas W. Herling
  • Substituted thienoimidazole derivatives, a process for the preparation thereof, pharmaceutical compositions containing them, and the use thereof as inhibitors of gastric acid secretion, as gastroprotectives and as medicaments for intestinal inflammations
    Patent number: 4956366
    Abstract: Substituted thienoimidazole derivatives, a process for the preparation thereof, pharmaceutical compositions containing them, and the use thereof as inhibitors of gastric acid secretion, as gastroprotectives and as medicaments for intestinal inflammationsThe invention relates to compounds of the formula ##STR1## in which A represents ##STR2## T denotes --S--, --SO-- or --SO.sub.2 --, R.sup.1 to R.sup.10, X, Y and Z have the meanings indicated in the description, to a process for the preparation thereof, to pharmaceutical compositions containing them, and to the use thereof as inhibitors of gastric acid secretion, as gastroprotectives and as medicaments for intestinal inflammations.
    Type: Grant
    Filed: July 13, 1988
    Date of Patent: September 11, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hildegard Nimmesgern, Klaus Weidmann, Hans-Jochen Lang, Robert Rippel, Andreas W. Herling