Abstract: Methods, apparatuses and systems are described for stent delivery and positioning to cover an access site. A stent delivery system may include a tubular member configured to advance through an access site and a primary constrainment member configured to releasably couple the stent to the tubular member. The stent delivery system may further include a secondary constrainment member at least partially disposed around the primary constrainment member, the stent, and the tubular member. In some cases, the tubular member and the primary constrainment member may be configured to reposition the stent within the body lumen after removal of the secondary constrainment member such that at least a portion of the stent covers the access site after withdrawal of the tubular member, the primary constrainment member, and the secondary constrainment member from the body lumen through the access site.

Abstract: Methods, apparatuses, and systems are described for minimizing various leakage effects of multi-zone ablation devices. Apparatuses may include an ablation device for treatment of tissue including an ablation structure with a plurality of bipolar electrode zones. Each of the zones may include an in-zone channel pair comprising a positive channel and a negative channel. The ablation structure may be configured such that, for any adjacent electrode zone pair comprising a first electrode zone and a second electrode zone adjacent to the first electrode zone, the positive channel of the first electrode zone is electrically distinct from the positive channel of the second electrode zone, and the negative channel of the first electrode zone is electrically distinct from the negative channel of the second electrode zone. Moreover, the ablation structure may be arranged such that a total number of electrically distinct channels that is less than twice a total number of the plurality of electrode zones.

Abstract: Methods, apparatuses, and systems are described for minimizing various leakage effects of multi-zone ablation devices. Apparatuses may include an ablation device for treatment of tissue including an ablation structure with a plurality of bipolar electrode zones. Each of the zones may include an in-zone channel pair comprising a positive channel and a negative channel. The ablation structure may be configured such that, for any adjacent electrode zone pair comprising a first electrode zone and a second electrode zone adjacent to the first electrode zone, the positive channel of the first electrode zone is electrically distinct from the positive channel of the second electrode zone, and the negative channel of the first electrode zone is electrically distinct from the negative channel of the second electrode zone. Moreover, the ablation structure may be arranged such that a total number of electrically distinct channels that is less than twice a total number of the plurality of electrode zones.

Abstract: Methods, systems, and devices for providing treatment to a target site are described. The system may include a guide assembly, an expandable support device coupled with the distal end of the guide assembly, and an operative member disposed on the expandable support device. The expandable support device may be configured to transition between a collapsed and expanded configuration. The expandable support device may be supported by one or more flexible supports aligned in parallel with an axis about which the expandable support device collapses and/or multiple splines arranged in a pattern configured to promote transitioning of the expandable support device between an expanded and collapsed configuration. The guide assembly may be configured to provide torque to the expandable support device. The operative member can include multiple electrodes arranged in parallel to the axis about which the expandable support device collapses.

Abstract: Methods, apparatuses, and systems are described for minimizing various leakage effects of multi-zone ablation devices. Apparatuses may include an ablation device for treatment of tissue including an ablation structure with a plurality of bipolar electrode zones. Each of the zones may include an in-zone channel pair comprising a positive channel and a negative channel. The ablation structure may be configured such that, for any adjacent electrode zone pair comprising a first electrode zone and a second electrode zone adjacent to the first electrode zone, the positive channel of the first electrode zone is electrically distinct from the positive channel of the second electrode zone, and the negative channel of the first electrode zone is electrically distinct from the negative channel of the second electrode zone. Moreover, the ablation structure may be arranged such that a total number of electrically distinct channels that is less than twice a total number of the plurality of electrode zones.

Abstract: An endoscopic surgical instrument deploys a hemostatic clip during endoscopic submucosal resection. The hemostatic clip has an elongated collar configured to be detachably coupled to a shaft of the surgical instrument, a pair of jaws received in the collar, and a magnet coupled to the jaws.

Abstract: Methods, systems, and devices are described for treating diseases of the gastrointestinal tract, including ulcerative colitis, by delivering ablative energy to a tissue surface of the gastrointestinal tract and ablating the tissue to a controlled depth. Ablating the tissue may include removing a biofilm layer or coagulating tissue.

Abstract: Methods, systems, and devices are described for treating diseases of the gastrointestinal tract, including ulcerative colitis, by delivering ablative energy to a tissue surface of the gastrointestinal tract and ablating the tissue to a controlled depth. Ablating the tissue may include removing a biofilm layer or coagulating tissue.

Abstract: Methods, apparatuses and systems are described for preventing the over-tightening of a furled ablation structure support around an expandable member. An ablation device for treatment of tissue in body lumens with varying sizes is disclosed. The ablation device may include a catheter, an expansion member coupled with a distal portion of the catheter, and an ablation structure support configured to at least partially unfurl or furl around the expansion member as the expansion member expands or contracts. The ablation device may further include a spacer coupled with the catheter and configured to limit a minimum diameter of the ablation structure support when the expansion member is completely contracted.

Abstract: Methods, systems, and devices for providing treatment to a tissue in body lumens are described. The system may include a catheter, an expansion member coupled with a distal portion of the catheter, an ablation structure including one or more longitudinal electrode segments, and an ablation structure support coupled to the ablation structure configured to at least partially unfurl as the expansion member expands and furl as the expansion member contracts. The ablation structure may include multiple separately wired and/or separately controlled longitudinal electrodes, longitudinal electrode zones, or both, such that each longitudinal electrode or longitudinal electrode zone may be selectively enabled or selectively disabled. In some instances, one or more springs are coupled to the ablation structure configured to promote unfurl or furl around the expansion member. In some instances, one or more protection elements are be positioned along the catheter.

Abstract: Methods, systems, and devices for providing treatment to a tissue in body lumens are described. The system may include a catheter, an expansion member coupled with a distal portion of the catheter, an ablation structure including one or more longitudinal electrode segments, and an ablation structure support coupled to the ablation structure configured to at least partially unfurl as the expansion member expands and furl as the expansion member contracts. The ablation structure may include multiple separately wired and/or separately controlled longitudinal electrodes, longitudinal electrode zones, or both, such that each longitudinal electrode or longitudinal electrode zone may be selectively enabled or selectively disabled. In some instances, one or more springs are coupled to the ablation structure configured to promote unfurl or furl around the expansion member. In some instances, one or more protection elements are be positioned along the catheter.

Abstract: Methods, systems, and devices for providing treatment to a tissue in body lumens are described. The system may include a catheter, an expansion member coupled with a distal portion of the catheter, an ablation structure including one or more longitudinal electrode segments, and an ablation structure support coupled to the ablation structure configured to at least partially unfurl as the expansion member expands and furl as the expansion member contracts. The ablation structure may include multiple separately wired and/or separately controlled longitudinal electrodes, longitudinal electrode zones, or both, such that each longitudinal electrode or longitudinal electrode zone may be selectively enabled or selectively disabled. In some instances, one or more springs are coupled to the ablation structure configured to promote unfurl or furl around the expansion member. In some instances, one or more protection elements are be positioned along the catheter.

Abstract: Methods, systems, and devices for providing treatment to a tissue in body lumens are described. The system may include a catheter, an expansion member coupled with a distal portion of the catheter, an ablation structure including one or more longitudinal electrode segments, and an ablation structure support coupled to the ablation structure configured to at least partially unfurl as the expansion member expands and furl as the expansion member contracts. The ablation structure may include multiple separately wired and/or separately controlled longitudinal electrodes, longitudinal electrode zones, or both, such that each longitudinal electrode or longitudinal electrode zone may be selectively enabled or selectively disabled. In some instances, one or more springs are coupled to the ablation structure configured to promote unfurl or furl around the expansion member. In some instances, one or more protection elements are be positioned along the catheter.

Abstract: Methods, systems, and devices for providing treatment to a target site are described. The system may include a guide assembly, an expandable support device coupled with the distal end of the guide assembly, and an operative member disposed on the expandable support device. The expandable support device may be configured to transition between a collapsed and expanded configuration. The expandable support device may be supported by one or more flexible supports aligned in parallel with an axis about which the expandable support device collapses and/or multiple splines arranged in a pattern configured to promote transitioning of the expandable support device between an expanded and collapsed configuration. The guide assembly may be configured to provide torque to the expandable support device. The operative member can include multiple electrodes arranged in parallel to the axis about which the expandable support device collapses.

Abstract: Methods, systems, and devices for providing treatment to a target site are described. The system may include a guide assembly, an expandable support device coupled with the distal end of the guide assembly, and an operative member disposed on the expandable support device. The expandable support device may be configured to transition between a collapsed and expanded configuration. The expandable support device may be supported by one or more flexible supports aligned in parallel with an axis about which the expandable support device collapses and/or multiple splines arranged in a pattern configured to promote transitioning of the expandable support device between an expanded and collapsed configuration. The guide assembly may be configured to provide torque to the expandable support device. The operative member can include multiple electrodes arranged in parallel to the axis about which the expandable support device collapses.

Abstract: Methods, systems, and devices for providing treatment to a target site are described. The system may include a guide assembly, an expandable support device coupled with the distal end of the guide assembly, and an operative member disposed on the expandable support device. The expandable support device may be configured to transition between a collapsed and expanded configuration. The expandable support device may be supported by one or more flexible supports aligned in parallel with an axis about which the expandable support device collapses and/or multiple splines arranged in a pattern configured to promote transitioning of the expandable support device between an expanded and collapsed configuration. The guide assembly may be configured to provide torque to the expandable support device. The operative member can include multiple electrodes arranged in parallel to the axis about which the expandable support device collapses.

Abstract: Methods, systems, and devices for providing treatment to a target site are described. The system may include a guide assembly, an expandable support device coupled with the distal end of the guide assembly, and an operative member disposed on the expandable support device. The expandable support device may be configured to transition between a collapsed and expanded configuration. The expandable support device may be supported by one or more flexible supports aligned in parallel with an axis about which the expandable support device collapses and/or multiple splines arranged in a pattern configured to promote transitioning of the expandable support device between an expanded and collapsed configuration. The guide assembly may be configured to provide torque to the expandable support device. The operative member can include multiple electrodes arranged in parallel to the axis about which the expandable support device collapses.

Abstract: Methods, apparatuses and systems are described for preventing the over-tightening of a furled ablation structure support around an expandable member. An ablation device for treatment of tissue in body lumens with varying sizes is disclosed. The ablation device may include a catheter, an expansion member coupled with a distal portion of the catheter, and an ablation structure support configured to at least partially unfurl or furl around the expansion member as the expansion member expands or contracts. The ablation device may further include a spacer coupled with the catheter and configured to limit a minimum diameter of the ablation structure support when the expansion member is completely contracted.

Abstract: Methods, apparatuses, and systems are described for minimizing various leakage effects of multi-zone ablation devices. Apparatuses may include an ablation device for treatment of tissue including an ablation structure with a plurality of bipolar electrode zones. Each of the zones may include an in-zone channel pair comprising a positive channel and a negative channel. The ablation structure may be configured such that, for any adjacent electrode zone pair comprising a first electrode zone and a second electrode zone adjacent to the first electrode zone, the positive channel of the first electrode zone is electrically distinct from the positive channel of the second electrode zone, and the negative channel of the first electrode zone is electrically distinct from the negative channel of the second electrode zone. Moreover, the ablation structure may be arranged such that a total number of electrically distinct channels that is less than twice a total number of the plurality of electrode zones.

Abstract: Methods, systems, and devices for providing treatment to a target site are described. The system may include a guide assembly, an expandable support device coupled with the distal end of the guide assembly, and an operative member disposed on the expandable support device. The expandable support device may be configured to transition between a collapsed and expanded configuration. The expandable support device may be supported by one or more flexible supports aligned in parallel with an axis about which the expandable support device collapses and/or multiple splines arranged in a pattern configured to promote transitioning of the expandable support device between an expanded and collapsed configuration. The guide assembly may be configured to provide torque to the expandable support device. The operative member can include multiple electrodes arranged in parallel to the axis about which the expandable support device collapses.