Patents by Inventor Hillel J. Chiel

Hillel J. Chiel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11786750
    Abstract: The present disclosure relates to modulating neural activity within brainstem circuitry to evoke a certain bodily function (e.g., cardiorespiratory response) in a patient. A controller can configure a light signal (such as an infrared light signal) to deliver an amount of radiant exposure to a specific portion of the brainstem for a time. The specific portion of the brainstem can include brainstem circuitry that is the control center for the certain bodily function. The configured light signal can be delivered to the specific portion of the brainstem by an optrode for the time. During application, the light signal can deliver the amount of radiant exposure to the specific portion of the brainstem to evoke the certain bodily function.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: October 17, 2023
    Assignees: CASE WESTERN RESERVE UNIVERSITY, VANDERBILT UNIVERSITY
    Inventors: Michael W. Jenkins, Stephen J. Lewis, Hillel J. Chiel, Eric Duco Jansen, Junqi Zhuo, Emilie Lothet, Gjinovefa Kola
  • Publication number: 20220161055
    Abstract: The present disclosure relates to using a light signal (e.g., an infrared (IR) light signal) for long-term modulation of peripheral nerve activity. Light generated with parameters (including intensity and time) can be applied to a peripheral nerve to achieve a target biological response. The target biological response can extend for a period after the light is applied. For example, when the light is applied for short period of time (e.g., 20 seconds), the target biological response can extend for a long period of time (e.g., over one hour).
    Type: Application
    Filed: February 8, 2022
    Publication date: May 26, 2022
    Inventors: Michael W. JENKINS, Stephen J. LEWIS, Hillel J. CHIEL, Eric Duco JANSEN, Junqi ZHOU, Emilie LOTHET, Gjinovefa KOLA
  • Publication number: 20210128913
    Abstract: Small-diameter axons can be targeted for neuromodulation. A nerve modulating therapy can be configured to target the small diameter axons in a target area of a subject specifically. The nerve modulating therapy can be applied to the target area to modulate conduction in one or more small diameter axons within the target area to a greater degree than in large diameter axons within the target area. The nerve modulating therapy can be any therapy that affects an outer surface of the one or more small diameter axons (like a heat signal, a pressure wave, an optogenetic manipulation, and/or a pharmaceutical dosage).
    Type: Application
    Filed: April 16, 2018
    Publication date: May 6, 2021
    Inventors: Emilie H. Lothet, Kendrick M. Shaw, Eric Duco Jansen, Hillel J. Chiel, Michael W. Jenkins, Charles C. Horn
  • Publication number: 20200406057
    Abstract: The present disclosure relates to modulating neural activity within brainstem circuitry to evoke a certain bodily function (e.g., cardiorespiratory response) in a patient. A controller can configure a light signal (such as an infrared light signal) to deliver an amount of radiant exposure to a specific portion of the brainstem for a time. The specific portion of the brainstem can include brainstem circuitry that is the control center for the certain bodily function. The configured light signal can be delivered to the specific portion of the brainstem by an optrode for the time. During application, the light signal can deliver the amount of radiant exposure to the specific portion of the brainstem to evoke the certain bodily function.
    Type: Application
    Filed: November 30, 2018
    Publication date: December 31, 2020
    Inventors: Michael W. JENKINS, Stephen J. LEWIS, Hillel J. CHIEL, Eric Duco JANSEN, Junqi ZHOU, Emilie LOTHET, Gjinovefa KOLA
  • Publication number: 20200324141
    Abstract: The present disclosure relates to a system for using a light signal (e.g., an infrared (IR) light signal) for long-term modulation of peripheral nerve activity. Light generated with parameters (including intensity and time) can be applied to a peripheral nerve to achieve a target biological response. The target biological response can extend for a period after the light is applied. For example, when the light is applied for short period of time (e.g., 20 seconds), the target biological response can extend for a long period of time (e.g., over one hour).
    Type: Application
    Filed: November 30, 2018
    Publication date: October 15, 2020
    Inventors: Michael W. JENKINS, Stephen J. LEWIS, Hillel J. CHIEL, Eric Duco JANSEN, Junqi ZHOU, Emilie LOTHET, Gjinovefa KOLA
  • Publication number: 20140074176
    Abstract: In one aspect of the present invention, a method of transient and selective suppression of neural activities of a target of interest, such as one or more nerves, includes selectively applying at least one light to the target of interest at selected locations with predetermined radiant exposures to create a localized and selective inhibitory response therein. The localized and selective inhibitory response comprises a local temperature change.
    Type: Application
    Filed: September 11, 2013
    Publication date: March 13, 2014
    Applicants: Case Western Reserve University, Vanderbilt University
    Inventors: E. Duco Jansen, Austin Robert Duke, Michael W. Jenkins, Hillel J. Chiel
  • Patent number: 6764441
    Abstract: Expandable actuators surround a central conduit. Each actuator comprises a bladder that, when fluid is introduced, expands laterally while contracting longitudinally. A restorative spring can be placed inside a bladder and between the two ends to restore the actuator to its original shape as fluid is withdrawn. Multiple actuators can be placed in series to successively inflate and deflate and generate a peristaltic motion. One or more Shape Memory Alloy (SMA) springs can be affixed to one or more restorative springs to cause bending motion.
    Type: Grant
    Filed: May 8, 2002
    Date of Patent: July 20, 2004
    Assignee: Case Western Reserve University
    Inventors: Hillel J. Chiel, Roger D. Quinn, Randall D. Beer, Elizabeth D. Mangan
  • Publication number: 20030065250
    Abstract: Expandable actuators surround a central conduit. Each actuator comprises a bladder that, when fluid is introduced, expands laterally while contracting longitudinally. A restorative spring can be placed inside a bladder and between the two ends to restore the actuator to its original shape as fluid is withdrawn. Multiple actuators can be placed in series to successively inflate and deflate and generate a peristaltic motion. One or more Shape Memory Alloy (SMA) springs can be affixed to one or more restorative springs to cause bending motion.
    Type: Application
    Filed: May 8, 2002
    Publication date: April 3, 2003
    Applicant: Case Western Reserve University
    Inventors: Hillel J. Chiel, Roger D. Quinn, Randall D. Beer, Elizabeth V. Mangan
  • Patent number: 5124918
    Abstract: A system for achieving ambulatory control of a multi-legged system employs stimulus and response-based modeling. A adapted neural network-based system is employed for dictating motion characteristics of a plurality of leg members. Rhythmic movements necessary to accomplish motion are provided by a series of signal generators. A first signal generator functions as a pacemaker governing overall system characteristics. One or more axis control signals are provided to a plurality of leg controllers, which axis control signals work in concert with a system coordination signal from the pacemaker. A sensory mechanism is also employed to govern ambulatory system responses.
    Type: Grant
    Filed: January 18, 1990
    Date of Patent: June 23, 1992
    Assignee: Case Western Reserve University
    Inventors: Randall D. Beer, Hillel J. Chiel, Leon S. Sterling