Patents by Inventor Hilmar Bischoff

Hilmar Bischoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted chromanol derivatives and their use
    Patent number: 8227511
    Abstract: The present invention relates to substituted chromanol derivatives, to processes for their preparation, to their use on their own or in combination for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders.
    Type: Grant
    Filed: March 7, 2007
    Date of Patent: July 24, 2012
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Carsten Schmeck, Hilmar Bischoff, Volkhart Li, Klemens Lustig, Michael Thutewohl, Alexandros Vakalopoulos, Olaf Weber
  • CHEMICAL COMPOUND AND ITS USE
    Publication number: 20120142728
    Abstract: The present application relates to a novel tetrahydroquinoline derivative, to a process for its preparation, to its use on its own or in combination for treating and/or preventing diseases and to its use for preparing medicaments, in particular as an inhibitor of the cholesterol ester transfer protein (CETP) for the treatment and/or prevention of cardiovascular disorders, in particular hypolipoproteinaemias, dyslipidaemias, hypertriglyceridaemias, hyperlipidaemias, hypercholesterolaemias and arteriosclerosis.
    Type: Application
    Filed: February 16, 2012
    Publication date: June 7, 2012
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Hilmar BISCHOFF, Heike GIELEN-HAERTWIG, Volkhart LI, Carsten SCHMECK, Michael THUTEWOHL, Alexandros VAKALOPOULOS, Olaf WEBER, Martina WUTTKE
  • Chemical compound and its use
    Patent number: 8124775
    Abstract: The present application relates to a novel tetrahydroquinoline derivative, to a process for its preparation, to its use on its own or in combination for treating and/or preventing diseases and to its use for preparing medicaments, in particular as an inhibitor of the cholesterol ester transfer protein (CETP) for the treatment and/or prevention of cardiovascular disorders, in particular hypolipoproteinaemias, dyslipidaemias, hypertriglyceridaemias, hyperlipidaemias, hypercholesterolaemias and arteriosclerosis.
    Type: Grant
    Filed: December 15, 2005
    Date of Patent: February 28, 2012
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Hilmar Bischoff, Heike Gielen-Haertwig, Volkhart Li, Carsten Schmeck, Michael Thutewohl, Alexandros Vakalopoulos, Olaf Weber, Martina Wuttke
  • Chemical compound and its use
    Patent number: 8039629
    Abstract: The present application relates to a novel tetrahydroquinoline derivative, to a process for its preparation, to its use on its own or in combination for treating and/or preventing diseases and to its use for preparing medicaments, in particular as an inhibitor of the cholesterol ester transfer protein (CETP) for the treatment and/or prevention of cardiovascular disorders, in particular hypolipoproteinaemias, dyslipidaemias, hypertriglyceridaemias, hyperlipidaemias, hypercholesterolaemias and arteriosclerosis.
    Type: Grant
    Filed: December 15, 2005
    Date of Patent: October 18, 2011
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Hilmar Bischoff, Heike Gielen-Haertwig, Volkhart Li, Carsten Schmeck, Michael Thutewohl, Alexandros Vakalopoulos, Olaf Weber, Martina Wuttke
  • Use of Adenosine A1 and/or Dual A1/2ab Agonists for Production of Medicaments for Treating Diseases
    Publication number: 20100048641
    Abstract: The present invention relates to the use of A1 and/or dual A1/A2b agonists of the formulae (IA) and (IB) for preparing a medicament for treating dyslipidemia, metabolic syndrome and diabetes and dyslipidemia, metabolic syndrome and diabetes in association with hypertension and cardiovascular disorders.
    Type: Application
    Filed: February 16, 2007
    Publication date: February 25, 2010
    Applicant: BAYER HEALTHCARE AG LAW AND PATENTS,PATENTS AND LICENSING
    Inventors: Peter Nell, Barbara Albrecht-Küpper, Walter Hübsch, Martina Wuttke, Thomas Krahn, Nicole Diedrichs, Hilmar Bischoff
  • Tetrahydrobenzo[d]azepin-2-one derivatives and the use thereof for treating cardiovascular diseases
    Patent number: 7662956
    Abstract: The present application relates to novel tetrahydrobenzo[d]azepin-2-one derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders, especially of dyslipidaemias, arteriosclerosis, restenosis and ischaemias.
    Type: Grant
    Filed: February 1, 2005
    Date of Patent: February 16, 2010
    Assignee: Bayer Shering Pharma AG
    Inventors: Nils Griebenow, Timo Flessner, Michael Härter, Martin Raabe, Anja Buchmüller, Hilmar Bischoff, Peter Ellinghaus, Peter Kolkhof
  • Substituted benzoxepino-isoxazoles and use thereof
    Publication number: 20100016299
    Abstract: The present application relates to novel substituted benzoxepinoisoxazole derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders, especially of dyslipidemias, arteriosclerosis, restenosis and ischemias.
    Type: Application
    Filed: June 28, 2007
    Publication date: January 21, 2010
    Applicant: BAYER HEALTHCARE AG
    Inventors: Nils Griebenow, Anja Buchmüller, Peter Kolkhof, Hilmar Bischoff
  • Substituted Chromanol Derivatives and Their Use
    Publication number: 20090306197
    Abstract: The present invention relates to substituted chromanol derivatives, to processes for their preparation, to their use on their own or in combination for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: March 7, 2007
    Publication date: December 10, 2009
    Applicant: Bayer Healthcare AG
    Inventors: Carsten Schmeck, Hilmar Bischoff, Volkhart Li, Klemens Lustig, Michael Thutewohl, Alexandros Vakalopoulos, Olaf Weber
  • Tricyclic benzazepine derivatives and their use
    Publication number: 20090215743
    Abstract: The present application relates to novel tricyclic benzazepine derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders, especially of dyslipidaemias, arteriosclerosis, restenosis and ischaemias.
    Type: Application
    Filed: December 31, 2004
    Publication date: August 27, 2009
    Applicant: Bayer HealthCare AG
    Inventors: Elisabeth Woltering, Michael Härter, Timo Flessner, Mario Jeske, Nils Griebenow, Frank Süssmeier, Hilmar Bischoff, Martin Raabe, Anja Buchmüller, Peter Kolkhof, Peter Ellinghaus, Olaf Weber
  • Novel Pyrimidine Derivatives and their Use
    Publication number: 20080261990
    Abstract: The present invention relates to novel pyrimidine derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular diseases, in particular dyslipidemias, arteriosclerosis, coronary heart disease, thrombosis and metabolic syndrome.
    Type: Application
    Filed: September 10, 2005
    Publication date: October 23, 2008
    Applicant: Bayer healthCare AG
    Inventors: Elke Dittrich-Wengenroth, Lars Barfacker, Axel Kretschmer, Claudia Hirth-Dietrich, Peter Ellinghaus, Martin Raabe, Hilmar Bischoff, Christian Pilger, Ulrich Rosentreter, Stephan Bartel, Klemens Lustig, Armin Kern, Dieter Lang, Marcus Bauser
  • Phenylthioacetic Acid Derivatives and Use Thereof
    Publication number: 20080255202
    Abstract: The present application relates to novel phenylthioacetic acid derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders, in particular dyslipidaemias and arteriosclerosis.
    Type: Application
    Filed: March 26, 2005
    Publication date: October 16, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Hilmar Bischoff, Elke Dittrich-Wengenroth, Nils Griebenow, Axel Kretschmer, Joachim Kruger, Elisabeth Woltering, Lars Barfacker, Claudia Hirth-Dietrich, Peter Ellinghaus, Martin Raabe, Stephen Bartel, Christian Pilger, Ulrich Rosentreter, Klemens Lustig, Armin Kern, Dieter Lang
  • Chemical Compound and Its Use
    Publication number: 20080255068
    Abstract: The present application relates to a novel tetrahydroquinoline derivative, to a process for its preparation, to its use on its own or in combination for treating and/or preventing diseases and to its use for preparing medicaments, in particular as an inhibitor of the cholesterol ester transfer protein (CETP) for the treatment and/or prevention of cardiovascular disorders, in particular hypolipoproteinaemias, dyslipidaemias, hypertriglyceridaemias, hyperlipidaemias, hypercholesterolaemias and arteriosclerosis.
    Type: Application
    Filed: December 15, 2005
    Publication date: October 16, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Hilmar Bischoff, Heike Gielen-Haertwig, Volkhart Li, Carsten Schmeck, Michael Thutewohl, Alexandros Vakalopoulos, Olaf Weber, Martina Wuttke
  • Chemical Compound and Its Use
    Publication number: 20080194609
    Abstract: The present application relates to novel tetrahydroquinoline derivatives, to a process for their preparation, to their use on their own or in combination for treating and/or preventing diseases and to their use for preparing medicaments, in particular as inhibitors of the cholesterol ester transfer protein (CETP) for the treatment and/or prevention of cardiovascular disorders, in particular hypolipoproteinemias, dyslipidemias, hypertriglyceridemias, hyperlipidemias, hypercholesterolemias and arteriosclerosis.
    Type: Application
    Filed: December 10, 2005
    Publication date: August 14, 2008
    Applicant: Bayer HeathCare AG
    Inventors: Hilmar Bischoff, Heike Gielen-Haertwig, Volkhart Li, Carsten Schmeck, Michael Thutewohl, Martina Wuttke, Alexandros Vakalopoulos, Olaf Weber
  • Tetrahydrobenzo(D)Azepin-2-One Derivatives and the Use Thereof for Treating Cardiovascular Diseases
    Publication number: 20070287698
    Abstract: The present application relates to novel tetrahydrobenzo[d]azepin-2-one derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders, especially of dyslipidaemias, arteriosclerosis, restenosis and ischaemias.
    Type: Application
    Filed: February 1, 2005
    Publication date: December 13, 2007
    Applicant: Bayer HealthCare AG
    Inventors: Nils Griebenow, Timo Flessner, Michael Harter, Martin Raabe, Anja Buchmuller, Hilmar Bischoff, Peter Ellinghaus, Peter Kolkhof
  • Novel Combination Containing a Stimulator of Soluble Guanylate Cyclase and a Lipid-Lowering Substance
    Publication number: 20070225299
    Abstract: A combination product which comprises as pharmaceutically active ingredients at least one active ingredient component A and at least one active ingredient component B, where active ingredient component A is a direct soluble guanylate cyclase stimulator of the formula (I) and active ingredient component B is a lipid-lowering agent, is described and claimed. Methods for treating various conditions using combination therapy are also claimed.
    Type: Application
    Filed: October 26, 2004
    Publication date: September 27, 2007
    Applicant: Bayer Healthcare AG
    Inventors: Hilmar Bischoff, Johannes-Peter Stasch, Stefan Weigand
  • Indole-phenylsulfonamide derivatives used as ppar-delta activating compounds
    Publication number: 20070149514
    Abstract: The invention relates to novel indole-phenylfulfonamide derivatives, to methods for the production thereof, and to their use in medicaments, particularly as potent PPAR-delta activating compounds, for the prevention and/or treatment of cardiovascular diseases, particularly dyslipidemias and coronary heart diseases.
    Type: Application
    Filed: December 24, 2003
    Publication date: June 28, 2007
    Applicant: Bayer HealthCare AG
    Inventors: Michael Woltering, Hilmar Bischoff, Elke Dittrich-Wengenroth, Heike Heckroth, Michael Otteneder
  • 4-HETEROARYL-TETRAHYDROQUINOLINES AND THEIR USE AS INHIBITORS OF THE CHOLESTERIN-ESTER TRANSFER PROTEIN
    Publication number: 20070142420
    Abstract: Hetero-tetrahydroquinolines can be prepared either by condensing correspondingly substituted hetero-tetrahydroquinoline aldehydes with the desired substituent or by reducing the corresponding keto-substituted hetero-tetrahydroquinolines, followed by introduction of the desired substituent by customary methods. The hetero-tetrahydroquinolines are suitable for use as active compounds in medicaments, in particular in medicaments for treating artheriosclerosis and dyslipidaemias.
    Type: Application
    Filed: February 22, 2007
    Publication date: June 21, 2007
    Applicant: BAYER AKTIENGESELLSCHAFT
    Inventors: JURGEN STOLTEFUSS, MICHAEL LOGERS, GUNTER SCHMIDT, ARNDT BRANDES, CARSTEN SCHMECK, KLAUS BREMM, HILMAR BISCHOFF, DELF SCHMIDT
  • Bicyclic indolinesulphonamide derivatives
    Publication number: 20070117860
    Abstract: The invention relates to novel bicyclic indoline sulfonamide derivatives of general formula (I), methods for the production thereof, and the use thereof in medicaments, especially as potent PPAR delta agonists for preventing and/or treating cardiovascular diseases, particularly dyslipidemia, arteriosclerosis, and coronary heart diseases.
    Type: Application
    Filed: July 20, 2004
    Publication date: May 24, 2007
    Applicant: BAYER HEALTHCARE AG
    Inventors: Elke Dittrich-Wengenroth, Hilmar Bischoff, Stephan Siegel, Michael Woltering
  • 4-Heteroaryl-tetrahydroquinolines and their use as inhibitors of the cholesterin-ester transfer protein
    Patent number: 7192971
    Abstract: Hetero-tetrahydroquinolines can be prepared either by condensing correspondingly substituted hetero-tetrahydroquinoline aldehydes with the desired substituent or by reducing the corresponding keto-substituted hetero-tetrahydroquinolines, followed by introduction of the desired substituent by customary methods. The hetero-tetrahydroquinolines are suitable for use as active compounds in medicaments, in particular in medicaments for treating artheriosclerosis and dyslipidaemias.
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: March 20, 2007
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jürgen Stoltefuss, Michael Lörges, Gunter Schmidt, Arndt Brandes, Carsten Schmeck, Klaus-Dieter Bremm, Hilmar Bischoff, Delf Schmidt
  • 2-Heteroaryl-imidazotriazinones and their use in the treatment of inflammatory or immune diseases
    Publication number: 20060293326
    Abstract: The invention relates to 2-Heteroaryl-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases.
    Type: Application
    Filed: May 21, 2002
    Publication date: December 28, 2006
    Inventors: Cristina Alonso-Alija, Heike Gielen, Martin Hendrix, Ulrich Niewohner, Maria Niewohner, Dagmar Schauss, Hilmar Bischoff, Nils Burkhardt, Volker Geiss, Karl-Heinz Schlemmer, Nigel Cuthbert, Mary Fitzgerald, Graham Sturton